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Julia TCW
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A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog
JK Ichida, J Blanchard, K Lam, EY Son, JE Chung, D Egli, KM Loh, ...
Cell stem cell 5 (5), 491-503, 2009
9542009
APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline
A Montagne, DA Nation, AP Sagare, G Barisano, MD Sweeney, ...
Nature 581 (7806), 71-76, 2020
8292020
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
M Xu, EM Lee, Z Wen, Y Cheng, WK Huang, X Qian, J Tcw, ...
Nature medicine 22 (10), 1101-1107, 2016
6852016
An efficient platform for astrocyte differentiation from human induced pluripotent stem cells
TCW Julia, M Wang, AA Pimenova, KR Bowles, BJ Hartley, E Lacin, ...
Stem cell reports 9 (2), 600-614, 2017
3572017
The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease
JY Hur, GR Frost, X Wu, C Crump, SJ Pan, E Wong, M Barros, T Li, P Nie, ...
Nature 586 (7831), 735-740, 2020
2562020
Genetics of β-amyloid precursor protein in Alzheimer's disease
TCW Julia, AM Goate
Cold Spring Harbor perspectives in medicine 7 (6), a024539, 2017
1792017
Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets
RA Neff, M Wang, S Vatansever, L Guo, C Ming, Q Wang, E Wang, ...
Science advances 7 (2), eabb5398, 2021
1582021
Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells
SM Ho, BJ Hartley, TCW Julia, M Beaumont, K Stafford, PA Slesinger, ...
Methods 101, 113-124, 2016
1532016
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain
Y Jiang, YHE Loh, P Rajarajan, T Hirayama, W Liao, BS Kassim, ...
Nature genetics 49 (8), 1239-1250, 2017
1452017
Cholesterol and matrisome pathways dysregulated in astrocytes and microglia
TCW Julia, L Qian, NH Pipalia, MJ Chao, SA Liang, Y Shi, BR Jain, ...
Cell 185 (13), 2213-2233. e25, 2022
1402022
Integration of Alzheimer’s disease genetics and myeloid genomics identifies disease risk regulatory elements and genes
G Novikova, M Kapoor, J Tcw, EM Abud, AG Efthymiou, SX Chen, ...
Nature communications 12 (1), 1610, 2021
1382021
Genetic architecture of Alzheimer's disease
SM Neuner, TCW Julia, AM Goate
Neurobiology of disease 143, 104976, 2020
942020
Construction of a large synthetic human scFv library with six diversified CDRs and high functional diversity
HY Yang, KJ Kang, JE Chung, H Shim
Molecules and cells 27, 225-235, 2009
812009
Notch inhibition allows oncogene-independent generation of iPS cells
JK Ichida, J Tcw, LA Williams, AC Carter, Y Shi, MT Moura, M Ziller, ...
Nature chemical biology 10 (8), 632-639, 2014
742014
CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states
K Leng, IVL Rose, H Kim, W Xia, W Romero-Fernandez, B Rooney, ...
Nature neuroscience 25 (11), 1528-1542, 2022
522022
MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer’s disease pathogenesis
J Cao, M Huang, L Guo, L Zhu, J Hou, L Zhang, A Pero, S Ng, ...
Molecular psychiatry 26 (9), 4687-4701, 2021
462021
Cholesterol and matrisome pathways dysregulated in human APOE ε4 glia
J Tcw, SA Liang, L Qian, NH Pipalia, MJ Chao, Y Shi, SE Bertelsen, ...
BioRxiv, 713362, 2019
432019
Human iPSC application in Alzheimer’s disease and Tau-related neurodegenerative diseases
T Julia
Neuroscience letters 699, 31-40, 2019
432019
Reduced variability of neural progenitor cells and improved purity of neuronal cultures using magnetic activated cell sorting
KR Bowles, J Tcw, L Qian, BM Jadow, AM Goate
PloS one 14 (3), e0213374, 2019
392019
Human iPSC-based modeling of central nerve system disorders for drug discovery
L Qian, J Tcw
International Journal of Molecular Sciences 22 (3), 1203, 2021
332021
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