Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria GA Biagini, N Fisher, AE Shone, MA Mubaraki, A Srivastava, A Hill, ... Proceedings of the National Academy of Sciences 109 (21), 8298-8303, 2012 | 193 | 2012 |
Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum Type II NADH: quinone oxidoreductase (PfNDH2) C Pidathala, R Amewu, B Pacorel, GL Nixon, P Gibbons, WD Hong, ... Journal of Medicinal Chemistry, 2012 | 129 | 2012 |
Identification, Design and Biological Evaluation of Heterocyclic Quinolones Targeting Plasmodium falciparum Type II NADH: Quinone Oxidoreductase (PfNDH2) SC Leung, P Gibbons, R Amewu, GL Nixon, C Pidathala, WD Hong, ... Journal of Medicinal Chemistry, 2012 | 69 | 2012 |
Cryopreservation-related loss of antigen-specific IFNγ producing CD4+ T-cells can skew immunogenicity data in vaccine trials: Lessons from a malaria vaccine trial substudy T Ford, C Wenden, A Mbekeani, L Dally, JH Cox, M Morin, N Winstone, ... Vaccine 35 (15), 1898-1906, 2017 | 43 | 2017 |
Complex interplay between sphingolipid and sterol metabolism revealed by perturbations to the leishmania metabolome caused by miltefosine EG Armitage, AQI Alqaisi, J Godzien, I Peña, AJ Mbekeani, ... Antimicrobial Agents and Chemotherapy 62 (5), 10.1128/aac. 02095-17, 2018 | 38 | 2018 |
Identification of Novel Antimalarial Chemotypes via Chemoinformatic Compound Selection Methods for a High Throughput Screening Program against the Novel Malarial Target, PfNDH2 … R Sharma, AS Lawrenson, N Fisher, A Warman, AE Shone, A Hill, ... Journal of Medicinal Chemistry, 2012 | 32 | 2012 |
The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis AQI Alqaisi, AJ Mbekeani, MB Llorens, AP Elhammer, PW Denny Parasitology 145 (2), 148-155, 2018 | 21 | 2018 |
Mining for natural product antileishmanials in a fungal extract library AJ Mbekeani, RS Jones, MB Llorens, J Elliot, C Regnault, MP Barrett, ... International Journal for Parasitology: Drugs and Drug Resistance 11, 118-128, 2019 | 11 | 2019 |
Functional Analyses of a Putative, Membrane-Bound, Peroxisomal Protein Import Mechanism from the Apicomplexan Protozoan Toxoplasma gondii AJ Mbekeani, WA Stanley, VC Kalel, N Dahan, E Zalckvar, L Sheiner, ... Genes 9 (9), 434, 2018 | 2 | 2018 |
A novel drug for uncomplicated malaria: Targeted high throughput screening (HTS) against the type II NADH: ubiquinone oxidoreductase (PfNDH2) of Plasmodium falciparum H Alasdair, M Alison, S Alison, N Gemma, S Paul, G Peter, A Richard, ... Malaria Journal 9, 2010 | 2 | 2010 |
Investigating Toxoplasma gondii peroxisome and the discovery of two Bisabolane Sesquiterpenes as anti-leshmanials. A MBEKEANI Durham University, 2020 | | 2020 |
IJP: Drugs and Drug Resistance AJ Mbekeani, RS Jones, MB Llorens, J Elliot, C Regnault, MP Barrett, ... | | 2019 |
CRYOPRESERVATION RELATED LOSS OF ANTIGEN SPECIFIC IFN gamma PRODUCING CD4+ T-CELLS: LESSONS FROM A MALARIA VACCINE TRIAL SUBSTUDY TP Ford, C Wenden, A Mbekeani, L Dally, JH Cox, N Winstone, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 95 (5), 314-314, 2017 | | 2017 |
Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH: quinone oxidoreductase (PfNDH2). CP Chandrakala Pidathala, R Amewu, B Pacorel, GL Nixon, P Gibbons, ... | | 2012 |
Development of a novel drug for uncomplicated malaria targeting the mitochondrial NADH: quinone oxidoreductase GA Biagini, A Hill, A Mbekeani, A Shone, G Nixon, P Stocks, P Gibbons, ... Malaria Journal 9, 1-1, 2010 | | 2010 |
View metadata, citation and similar papers at core. ac. uk N Messadeq, J Milne, P Lambert, P Elliott, B Geny, M Laakso, N Fisher, ... | | |
9P. 3 A novel drug for uncomplicated malaria: Targeted high throughput screening (HTS) against the type II NADH: ubiquinone oxidoreductase (PfNDH2) of Plasmodium falciparum N Fisher, A Hill, A Mbekeani, A Shone, G Nixon, P Stocks, P Gibbons, ... | | |
Development of a novel drug for uncomplicated malaria targeting the mitochondrial NADH: quinone oxidoreductase B Giancarlo, H Alasdair, M Alison, S Alison, N Gemma, S Paul, G Peter, ... Malaria Journal 9, 0 | | |