| Stochastic induction of persister cells by HipA through (p) ppGpp-mediated activation of mRNA endonucleases E Germain, M Roghanian, K Gerdes, E Maisonneuve Proceedings of the National Academy of Sciences 112 (16), 5171-5176, 2015 | 171 | 2015 |
| Stepwise mechanism for transcription fidelity Y Yuzenkova, A Bochkareva, VR Tadigotla, M Roghanian, S Zorov, ... BMC biology 8, 1-15, 2010 | 109 | 2010 |
| Activation of the stringent response by loading of RelA-tRNA complexes at the ribosomal A-site KS Winther, M Roghanian, K Gerdes Molecular cell 70 (1), 95-105. e4, 2018 | 101 | 2018 |
| Bacterial global regulators DksA/ppGpp increase fidelity of transcription M Roghanian, N Zenkin, Y Yuzenkova Nucleic acids research 43 (3), 1529-1536, 2015 | 66 | 2015 |
| Controlled interplay between trigger loop and Gre factor in the RNA polymerase active centre M Roghanian, Y Yuzenkova, N Zenkin Nucleic acids research 39 (10), 4352-4359, 2011 | 62 | 2011 |
| The C-terminal RRM/ACT domain is crucial for fine-tuning the activation of ‘long’RelA-SpoT Homolog enzymes by ribosomal complexes H Takada, M Roghanian, V Murina, I Dzhygyr, R Murayama, G Akanuma, ... Frontiers in microbiology 11, 277, 2020 | 50 | 2020 |
| (p)ppGpp-mediated stress response induced by defects in outer membrane biogenesis and ATP production promotes survival in Escherichia coli M Roghanian, S Semsey, A Løbner-Olesen, F Jalalvand Scientific Reports 9 (1), 2934, 2019 | 36 | 2019 |
| Intramolecular Interactions Dominate the Autoregulation of Escherichia coli Stringent Factor RelA KJ Turnbull, I Dzhygyr, S Lindemose, V Hauryliuk, M Roghanian Frontiers in microbiology 10, 1966, 2019 | 34 | 2019 |
| Fatty acid starvation activates RelA by depleting lysine precursor pyruvate AK Sinha, KS Winther, M Roghanian, K Gerdes Molecular Microbiology 112 (4), 1339-1349, 2019 | 32 | 2019 |
| Tagetitoxin inhibits transcription by stabilizing pre-translocated state of the elongation complex Y Yuzenkova, M Roghanian, A Bochkareva, N Zenkin Nucleic acids research 41 (20), 9257-9265, 2013 | 32 | 2013 |
| Ribosome association primes the stringent factor Rel for tRNA-dependent locking in the A-site and activation of (p) ppGpp synthesis H Takada, M Roghanian, J Caballero-Montes, K Van Nerom, S Jimmy, ... Nucleic acids research 49 (1), 444-457, 2021 | 31 | 2021 |
| RelA-SpoT Homolog toxins pyrophosphorylate the CCA end of tRNA to inhibit protein synthesis T Kurata, T Brodiazhenko, SRA Oliveira, M Roghanian, Y Sakaguchi, ... Molecular cell 81 (15), 3160-3170. e9, 2021 | 30 | 2021 |
| (p) ppGpp controls stringent factors by exploiting antagonistic allosteric coupling between catalytic domains M Roghanian, K Van Nerom, H Takada, J Caballero-Montes, H Tamman, ... Molecular cell 81 (16), 3310-3322. e6, 2021 | 24 | 2021 |
| Rapid curtailing of the stringent response by toxin-antitoxin module-encoded mRNases C Tian, M Roghanian, MG Jørgensen, K Sneppen, MA Sørensen, ... Journal of bacteriology 198 (14), 1918-1926, 2016 | 23 | 2016 |
| Photorhabdus antibacterial Rhs polymorphic toxin inhibits translation through ADP-ribosylation of 23S ribosomal RNA D Jurėnas, A Payelleville, M Roghanian, KJ Turnbull, A Givaudan, ... Nucleic acids research 49 (14), 8384-8395, 2021 | 21 | 2021 |
| Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase S Vang Nielsen, KJ Turnbull, M Roghanian, R Bærentsen, M Semanjski, ... MBio 10 (3), e01138-19, 2019 | 21* | 2019 |
| Alarmone (p)ppGpp regulates the transition from pathogenicity to mutualism in Photorhabdus luminescens R Bager, M Roghanian, K Gerdes, DJ Clarke Molecular Microbiology 100 (4), 735-747, 2016 | 15 | 2016 |
| Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes TO Koller, KJ Turnbull, K Vaitkevicius, C Crowe-McAuliffe, M Roghanian, ... Nucleic Acids Research 50 (19), 11285-11300, 2022 | 12 | 2022 |
| Multiple active centers of multi-subunit RNA polymerases Y Yuzenkova, M Roghanian, N Zenkin Transcription 3 (3), 115-118, 2012 | 11 | 2012 |
| Structure of SpoT reveals evolutionary tuning of catalysis via conformational constraint H Tamman, K Ernits, M Roghanian, A Ainelo, C Julius, A Perrier, ... Nature chemical biology 19 (3), 334-345, 2023 | 7 | 2023 |
