| Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ... Cancer discovery 5 (12), 1282-1295, 2015 | 1198 | 2015 |
| Control of alternative splicing in immune responses: many regulators, many predictions, much still to learn NM Martinez, KW Lynch Immunological reviews 253 (1), 216-236, 2013 | 191 | 2013 |
| Regulation and function of RNA pseudouridylation in human cells EK Borchardt, NM Martinez, WV Gilbert Annual review of genetics 54, 309-336, 2020 | 112 | 2020 |
| Alternative splicing networks regulated by signaling in human T cells NM Martinez, Q Pan, BS Cole, CA Yarosh, GA Babcock, F Heyd, W Zhu, ... Rna 18 (5), 1029-1040, 2012 | 109 | 2012 |
| mRNA structure determines modification by pseudouridine synthase 1 TM Carlile, NM Martinez, C Schaening, A Su, TA Bell, B Zinshteyn, ... Nature chemical biology 15 (10), 966-974, 2019 | 107 | 2019 |
| Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing NM Martinez, A Su, MC Burns, JK Nussbacher, C Schaening, S Sathe, ... Molecular cell 82 (3), 645-659. e9, 2022 | 102 | 2022 |
| Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation NM Martinez, L Agosto, J Qiu, MJ Mallory, MR Gazzara, Y Barash, X Fu, ... Genes & development 29 (19), 2054-2066, 2015 | 74 | 2015 |
| Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling MJ Mallory, SJ Allon, J Qiu, MR Gazzara, I Tapescu, NM Martinez, XD Fu, ... Proceedings of the National Academy of Sciences 112 (17), E2139-E2148, 2015 | 69 | 2015 |
| Position-dependent activity of CELF2 in the regulation of splicing and implications for signal-responsive regulation in T cells S Ajith, MR Gazzara, BS Cole, G Shankarling, NM Martinez, MJ Mallory, ... RNA biology 13 (6), 569-581, 2016 | 47 | 2016 |
| Pre‐mRNA modifications and their role in nuclear processing NM Martinez, WV Gilbert Quantitative Biology 6 (3), 210-227, 2018 | 27 | 2018 |
| Inhibition of zinc-dependent histone deacetylases with a chemically triggered electrophile ZV Boskovic, MM Kemp, AM Freedy, VS Viswanathan, MS Pop, JH Fuller, ... ACS Chemical Biology 11 (7), 1844-1851, 2016 | 27 | 2016 |
| A novel HDAC inhibitor with a hydroxy-pyrimidine scaffold MM Kemp, Q Wang, JH Fuller, N West, NM Martinez, EM Morse, ... Bioorganic & medicinal chemistry letters 21 (14), 4164-4169, 2011 | 27 | 2011 |
| Convergence of acquired mutations and alternative splicing of CD19 enables resistance to CART-19 immunotherapy. Cancer Discov 5: 1282–1295 E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ... Nat Med 24, 1504-1506, 2015 | 22 | 2015 |
| Pseudouridine site assignment by high-throughput in vitro RNA pseudouridylation and sequencing NM Martinez, C Schaening-Burgos, WV Gilbert Methods in enzymology 658, 277-310, 2021 | 3 | 2021 |
| Alternative splicing of CD19 mRNA in leukemias escaping CART-19 immunotherapy eliminates the cognate epitope and contributes to treatment failure E Sotillo, D Barrett, A Bagashev, K Black, C Lanauze, D Oldridge, ... Cancer Research 75 (15_Supplement), 3143-3143, 2015 | 3 | 2015 |
| Why U matters: detection and functions of pseudouridine modifications in mRNAs R Rodell, N Robalin, NM Martinez Trends in Biochemical Sciences, 2024 | 2 | 2024 |
| Investigating pseudouridylation mechanisms by high-throughput in vitro RNA pseudouridylation and sequencing NM Martinez, WV Gilbert RNA Modifications: Methods and Protocols, 379-397, 2021 | 2 | 2021 |
| Regulation of CD19 Exon 2 inclusion in B-lymphoid cells by splicing factors and epigenetic marks K Black, E Sotillo, N Martinez, M Gazzara, A Barrera, Y Barash, K Lynch, ... Blood 126 (23), 2425, 2015 | 2 | 2015 |
| Rewriting the message: Harnessing RNA pseudouridylation to tackle disease M Montes, NM Martínez Molecular Cell 83 (4), 503-506, 2023 | 1 | 2023 |
| Interplay between signaling and splicing during T cell activation: A study on MKK7 NM Martinez University of Pennsylvania, 2015 | | 2015 |
