| A human pluripotent stem cell-based platform to study SARS-CoV-2 tropism and model virus infection in human cells and organoids L Yang, Y Han, BE Nilsson-Payant, V Gupta, P Wang, X Duan, X Tang, ... Cell stem cell 27 (1), 125-136. e7, 2020 | 654 | 2020 |
| Identification of SARS-CoV-2 inhibitors using lung and colonic organoids Y Han, X Duan, L Yang, BE Nilsson-Payant, P Wang, F Duan, X Tang, ... Nature 589 (7841), 270-275, 2021 | 462 | 2021 |
| A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells P Bu, KY Chen, JH Chen, L Wang, J Walters, YJ Shin, JP Goerger, J Sun, ... Cell stem cell 12 (5), 602-615, 2013 | 392 | 2013 |
| Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing M Crespo, E Vilar, SY Tsai, K Chang, S Amin, T Srinivasan, T Zhang, ... Nature medicine 23 (7), 878-884, 2017 | 337 | 2017 |
| Inhibition of human cancer cell line growth and human umbilical vein endothelial cell angiogenesis by artemisinin derivatives in vitro HH Chen, HJ Zhou, X Fang Pharmacological research 48 (3), 231-236, 2003 | 294 | 2003 |
| Inhibitory effects of artesunate on angiogenesis and on expressions of vascular endothelial growth factor and VEGF receptor KDR/flk-1 HH Chen, HJ Zhou, GD Wu, XE Lou Pharmacology 71 (1), 1-9, 2004 | 195 | 2004 |
| Antimalarial dihydroartemisinin also inhibits angiogenesis HH Chen, HJ Zhou, WQ Wang, GD Wu Cancer chemotherapy and pharmacology 53, 423-432, 2004 | 162 | 2004 |
| Exosomes: Small vesicles with big roles in cancer, vaccine development, and therapeutics A Thakur, DC Parra, P Motallebnejad, M Brocchi, HJ Chen Bioactive materials 10, 281-294, 2022 | 151 | 2022 |
| A miR-34a-numb feedforward loop triggered by inflammation regulates asymmetric stem cell division in intestine and colon cancer P Bu, L Wang, KY Chen, T Srinivasan, PKL Murthy, KL Tung, AK Varanko, ... Cell stem cell 18 (2), 189-202, 2016 | 148 | 2016 |
| New approaches to SCLC therapy: from the laboratory to the clinic JT Poirier, J George, TK Owonikoko, A Berns, E Brambilla, LA Byers, ... Journal of Thoracic Oncology 15 (4), 520-540, 2020 | 144 | 2020 |
| A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division L Wang, P Bu, Y Ai, T Srinivasan, HJ Chen, K Xiang, SM Lipkin, X Shen Elife 5, e14620, 2016 | 129 | 2016 |
| miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β P Bu, L Wang, KY Chen, N Rakhilin, J Sun, A Closa, KL Tung, S King, ... Nature communications 6 (1), 6879, 2015 | 126 | 2015 |
| Artesunate reduces chicken chorioallantoic membrane neovascularisation and exhibits antiangiogenic and apoptotic activity on human microvascular dermal endothelial cell C Huan-huan, Y Li-Li, L Shang-Bin Cancer letters 211 (2), 163-173, 2004 | 106 | 2004 |
| Identification of candidate COVID-19 therapeutics using hPSC-derived lung organoids Y Han, L Yang, X Duan, F Duan, BE Nilsson-Payant, TM Yaron, P Wang, ... BioRxiv, 2020.05. 05.079095, 2020 | 98 | 2020 |
| A recellularized human colon model identifies cancer driver genes HJ Chen, Z Wei, J Sun, A Bhattacharya, DJ Savage, R Serda, Y Mackeyev, ... Nature biotechnology 34 (8), 845-851, 2016 | 97 | 2016 |
| A pumpless body-on-a-chip model using a primary culture of human intestinal cells and a 3D culture of liver cells HJ Chen, P Miller, ML Shuler Lab on a Chip 18 (14), 2036-2046, 2018 | 94 | 2018 |
| Chemokine 25–induced signaling suppresses colon cancer invasion and metastasis HJ Chen, R Edwards, S Tucci, P Bu, J Milsom, S Lee, W Edelmann, ... The Journal of clinical investigation 122 (9), 3184-3196, 2012 | 91 | 2012 |
| Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells HJ Chen, A Poran, AM Unni, SX Huang, O Elemento, HW Snoeck, ... Journal of Experimental Medicine 216 (3), 674-687, 2019 | 74 | 2019 |
| The mini player with diverse functions: extracellular vesicles in cell biology, disease, and therapeutics A Thakur, X Ke, YW Chen, P Motallebnejad, K Zhang, Q Lian, HJ Chen Protein & cell 13 (9), 631-654, 2022 | 68 | 2022 |
| Differential effects of macrophage subtypes on SARS-CoV-2 infection in a human pluripotent stem cell-derived model Q Lian, K Zhang, Z Zhang, F Duan, L Guo, W Luo, BWY Mok, A Thakur, ... Nature communications 13 (1), 2028, 2022 | 47 | 2022 |
Xiling ShenAssociate Professor of Biomedical Engineering, Duke UniversityVerified email at duke.edu
