Role of the heme active site and protein environment in structure, spectra, and function of the cytochrome P450s GH Loew, DL Harris Chemical Reviews 100 (2), 407-420, 2000 | 356 | 2000 |
Theoretical investigation of the proton assisted pathway to formation of cytochrome P450 compound I DL Harris, GH Loew Journal of the American Chemical Society 120 (35), 8941-8948, 1998 | 237 | 1998 |
High-valent intermediates of heme proteins and model compounds DL Harris Current Opinion in Chemical Biology 5 (6), 724-735, 2001 | 151 | 2001 |
Photophysics of tryptophan in bacteriophage T4 lysozymes DL Harris, BS Hudson Biochemistry 29 (22), 5276-5285, 1990 | 94 | 1990 |
Theoretical study of the ligand–CYP2B4 complexes: effect of structure on binding free energies and heme spin state DL Harris, JY Park, L Gruenke, L Waskell Proteins: Structure, Function, and Bioinformatics 55 (4), 895-914, 2004 | 79 | 2004 |
Identification of putative peroxide intermediates of peroxidases by electronic structure and spectra calculations DL Harris, GH Loew Journal of the American Chemical Society 118 (43), 10588-10594, 1996 | 75 | 1996 |
An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear … MI Dawson, Z Xia, G Liu, JA Fontana, L Farhana, BB Patel, ... Journal of medicinal chemistry 50 (11), 2622-2639, 2007 | 69 | 2007 |
Investigation of the proton-assisted pathway to formation of the catalytically active, ferryl species of P450s by molecular dynamics studies of P450eryF DL Harris, GH Loew Journal of the American Chemical Society 118 (27), 6377-6387, 1996 | 58 | 1996 |
Regulation of the Apelinergic System and Its Potential in Cardiovascular Disease: Peptides and Small Molecules as Tools for Discovery: Miniperspective S Narayanan, DL Harris, R Maitra, SP Runyon Journal of medicinal chemistry 58 (20), 7913-7927, 2015 | 55 | 2015 |
Proton-transfer dynamics in the activation of cytochrome P450eryF V Guallar, DL Harris, VS Batista, WH Miller Journal of the American Chemical Society 124 (7), 1430-1437, 2002 | 54 | 2002 |
Antagonist analogue of 6-[3 ‘-(1-adamantyl)-4 ‘-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN) family of apoptosis inducers that effectively blocks AHPN-induced apoptosis … MI Dawson, DL Harris, G Liu, PD Hobbs, CW Lange, L Jong, ... Journal of medicinal chemistry 47 (14), 3518-3536, 2004 | 50 | 2004 |
Determination of the rate of reduction of oxyferrous cytochrome P450 2B4 by 5-deazariboflavin adenine dinucleotide T491V cytochrome P450 reductase H Zhang, L Gruenke, D Arscott, A Shen, C Kasper, DL Harris, ... Biochemistry 42 (40), 11594-11603, 2003 | 48 | 2003 |
Metabolism of bergamottin by cytochromes P450 2B6 and 3A5 UM Kent, H Lin, KR Noon, DL Harris, PF Hollenberg Journal of Pharmacology and Experimental Therapeutics 318 (3), 992-1005, 2006 | 46 | 2006 |
Metabolism of bergamottin by cytochromes P450 2B6 and 3A5 UM Kent, H Lin, KR Noon, DL Harris, PF Hollenberg Journal of Pharmacology and Experimental Therapeutics 318 (3), 992-1005, 2006 | 46 | 2006 |
A role for Thr 252 in cytochrome P450cam oxygen activation DL Harris, GH Loew Journal of the American Chemical Society 116 (26), 11671-11674, 1994 | 46 | 1994 |
Cytochrome P450nor: a nitric oxide reductase—structure, spectra, and mechanism DL Harris International journal of quantum chemistry 88 (1), 183-200, 2002 | 43 | 2002 |
Oxidation and electronic state dependence of proton transfer in the enzymatic cycle of cytochrome P450eryF DL Harris Journal of inorganic biochemistry 91 (4), 568-585, 2002 | 42 | 2002 |
Identifying structural determinants of potency for analogs of apelin-13: integration of C-terminal truncation with structure–activity Y Zhang, R Maitra, DL Harris, S Dhungana, R Snyder, SP Runyon Bioorganic & medicinal chemistry 22 (11), 2992-2997, 2014 | 39 | 2014 |
Substituted tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor DA Perrey, NA German, BP Gilmour, JX Li, DL Harris, BF Thomas, ... Journal of medicinal chemistry 56 (17), 6901-6916, 2013 | 39 | 2013 |
Selective Influence on Contextual Memory: Physiochemical Properties Associated with Selectivity of Benzodiazepine Ligands at GABAA Receptors Containing the … D Harris, T Clayton, J Cook, P Sahbaie, RF Halliwell, R Furtmüller, ... Journal of medicinal chemistry 51 (13), 3788-3803, 2008 | 39 | 2008 |