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Karthickeyan Chella Krishnan
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Integration of multi-omics data from mouse diversity panel highlights mitochondrial dysfunction in non-alcoholic fatty liver disease
KC Krishnan, Z Kurt, R Barrere-Cain, S Sabir, A Das, R Floyd, L Vergnes, ...
Cell systems 6 (1), 103-115. e7, 2018
1262018
Sex differences in metabolism and cardiometabolic disorders
KC Krishnan, M Mehrabian, AJ Lusis
Current opinion in lipidology 29 (5), 404-410, 2018
1032018
Gene-by-sex interactions in mitochondrial functions and cardio-metabolic traits
F Norheim, Y Hasin-Brumshtein, L Vergnes, KC Krishnan, C Pan, ...
Cell metabolism 29 (4), 932-949. e4, 2019
872019
A strategy for discovery of endocrine interactions with application to whole-body metabolism
MM Seldin, S Koplev, P Rajbhandari, L Vergnes, GM Rosenberg, Y Meng, ...
Cell metabolism 27 (5), 1138-1155. e6, 2018
672018
The genetic architecture of diet‐induced hepatic fibrosis in mice
ST Hui, Z Kurt, I Tuominen, F Norheim, R C. Davis, C Pan, DL Dirks, ...
Hepatology 68 (6), 2182-2196, 2018
632018
Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity
R Acín-Pérez, S Iborra, Y Martí-Mateos, ECL Cook, R Conde-Garrosa, ...
Nature metabolism 2 (9), 974-988, 2020
492020
Sex-specific metabolic functions of adipose Lipocalin-2
KC Krishnan, S Sabir, M Shum, Y Meng, R Acín-Pérez, JM Lang, ...
Molecular Metabolism 30, 30-47, 2019
462019
Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle
PJ Ferrara, X Rong, JA Maschek, ARP Verkerke, P Siripoksup, H Song, ...
The Journal of clinical investigation 131 (8), 2021
442021
Liver pyruvate kinase promotes NAFLD/NASH in both mice and humans in a sex-specific manner
KC Krishnan, RR Floyd, S Sabir, DW Jayasekera, PV Leon-Mimila, ...
Cellular and molecular gastroenterology and hepatology 11 (2), 389-406, 2021
382021
Sex differences in heart mitochondria regulate diastolic dysfunction
Y Cao, L Vergnes, YC Wang, C Pan, K Chella Krishnan, TM Moore, ...
Nature communications 13 (1), 3850, 2022
372022
Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2
K Chella Krishnan, L Vergnes, R Acín-Pérez, L Stiles, M Shum, L Ma, ...
Nature metabolism 3 (11), 1552-1568, 2021
352021
A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains
S Mairpady Shambat, N Siemens, IR Monk, DB Mohan, S Mukundan, ...
Scientific reports 6 (1), 31360, 2016
342016
Genetic architecture of group A streptococcal necrotizing soft tissue infections in the mouse
K Chella Krishnan, S Mukundan, J Alagarsamy, J Hur, S Nookala, ...
PLoS pathogens 12 (7), e1005732, 2016
342016
ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity
M Shum, CA Shintre, T Althoff, V Gutierrez, M Segawa, AD Saxberg, ...
Science translational medicine 13 (594), eabd1869, 2021
292021
Genetic, dietary, and sex-specific regulation of hepatic ceramides and the relationship between hepatic ceramides and IR [S]
F Norheim, T Bjellaas, ST Hui, KC Krishnan, J Lee, S Gupta, C Pan, ...
Journal of lipid research 59 (7), 1164-1174, 2018
292018
Differential metabolic and multi-tissue transcriptomic responses to fructose consumption among genetically diverse mice
G Zhang, HR Byun, Z Ying, M Blencowe, Y Zhao, J Hong, L Shu, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (1), 165569, 2020
272020
Metal-mediated modulation of streptococcal cysteine protease activity and its biological implications
K Chella Krishnan, S Mukundan, JA Landero Figueroa, JA Caruso, ...
Infection and Immunity 82 (7), 2992-3001, 2014
232014
Recruitment and remodeling of peridroplet mitochondria in human adipose tissue
R Acín-Perez, A Petcherski, M Veliova, IY Benador, EA Assali, ...
Redox Biology 46, 102087, 2021
182021
Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis
F Norheim, K Chella Krishnan, T Bjellaas, L Vergnes, C Pan, BW Parks, ...
Molecular systems biology 17 (1), e9684, 2021
142021
Host genetic variations and sex differences potentiate predisposition, severity, and outcomes of group A Streptococcus-mediated necrotizing soft tissue infections
K Chella Krishnan, S Mukundan, J Alagarsamy, D Laturnus, M Kotb
Infection and immunity 84 (2), 416-424, 2016
132016
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