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Nicolas J Wheeler
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Comparative genomics of the major parasitic worms
Nature genetics 51 (1), 163-174, 2019
3712019
Genetic and functional diversification of chemosensory pathway receptors in mosquito-borne filarial nematodes
NJ Wheeler, ZW Heimark, PM Airs, A Mann, LC Bartholomay, ...
Plos Biology 18 (6), e3000723, 2020
322020
Gene drives for schistosomiasis transmission control
T Maier, NJ Wheeler, EKO Namigai, J Tycko, RE Grewelle, ...
PLoS neglected tropical diseases 13 (12), e0007833, 2019
312019
Tissue-specific transcriptome analyses provide new insights into GPCR signalling in adult Schistosoma mansoni
S Hahnel, N Wheeler, Z Lu, A Wangwiwatsin, P McVeigh, A Maule, ...
PLoS pathogens 14 (1), e1006718, 2018
302018
Ivermectin inhibits extracellular vesicle secretion from parasitic nematodes
HJ Loghry, W Yuan, M Zamanian, NJ Wheeler, TA Day, MJ Kimber
Journal of extracellular vesicles 10 (2), e12036, 2020
272020
Novel RNAi-mediated approach to G protein-coupled receptor deorphanization: proof of principle and characterization of a planarian 5-HT receptor
M Zamanian, PN Agbedanu, NJ Wheeler, P McVeigh, MJ Kimber, TA Day
PLoS One 7 (7), e40787, 2012
192012
Functional analysis of Girardia tigrina transcriptome seeds pipeline for anthelmintic target discovery
NJ Wheeler, PN Agbedanu, MJ Kimber, P Ribeiro, TA Day, M Zamanian
Parasites & vectors 8, 1-12, 2015
132015
Spatial transcriptomics reveals antiparasitic targets associated with essential behaviors in the human parasite Brugia malayi
PM Airs, K Vaccaro, KJ Gallo, N Dinguirard, ZW Heimark, NJ Wheeler, ...
PLoS pathogens 18 (4), e1010399, 2022
122022
Sequence and structural variation in the genome of the Biomphalaria glabrata embryonic (Bge) cell line
NJ Wheeler, N Dinguirard, J Marquez, A Gonzalez, M Zamanian, ...
Parasites & vectors 11, 1-12, 2018
102018
Long-read RNA sequencing of human and animal filarial parasites improves gene models and discovers operons
NJ Wheeler, PM Airs, M Zamanian
PLoS Neglected Tropical Diseases 14 (11), e0008869, 2020
92020
wrmXpress: A modular package for high-throughput image analysis of parasitic and free-living worms
NJ Wheeler, KJ Gallo, EJG Rehborg, KT Ryan, JD Chan, M Zamanian
PLOS Neglected Tropical Diseases 16 (11), e0010937, 2022
72022
Multivariate chemogenomic screening prioritizes new macrofilaricidal leads
NJ Wheeler, KT Ryan, KJ Gallo, CR Henthorn, SS Ericksen, JD Chan, ...
Communications Biology 6 (1), 44, 2023
52023
Making sense of sensory behaviors in vector-borne helminths
NJ Wheeler, EA Hallem, M Zamanian
Trends in parasitology 38 (10), 841-853, 2022
52022
Phenotypic Profiling of Macrocyclic Lactones on Parasitic Schistosoma Flatworms
KT Ryan, NJ Wheeler, IK Kamara, H Johnson, JE Humphries, ...
Antimicrobial Agents and Chemotherapy 67 (2), e01230-22, 2023
42023
Extracellular vesicles secreted by Brugia malayi microfilariae modulate the melanization pathway in the mosquito host
HJ Loghry, H Kwon, RC Smith, NA Sondjaja, SJ Minkler, S Young, ...
Scientific Reports 13 (1), 8778, 2023
22023
Pharmacological profiling of a Brugia malayi muscarinic acetylcholine receptor as a putative antiparasitic target
KJ Gallo, NJ Wheeler, AM Elmi, PM Airs, M Zamanian
Antimicrobial Agents and Chemotherapy 67 (1), e01188-22, 2023
22023
A high-throughput sensory assay for parasitic and free-living nematodes
LR Nunn, TD Juang, DJ Beebe, NJ Wheeler, M Zamanian
Integrative Biology 15, zyad010, 2023
1*2023
Annotation of G-Protein Coupled Receptors in the Genomes of Parasitic Blood Flukes
IK Kamara, JT Thao, K Kaur, NJ Wheeler, JD Chan
microPublication Biology 2023, 2023
12023
Mapping resistance-associated anthelmintic interactions in the model nematode Caenorhabditis elegans
EG Rehborg, NJ Wheeler, M Zamanian
PLOS Neglected Tropical Diseases 17 (10), e0011705, 2023
2023
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Articles 1–19