| Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases AL Cardoso, A Fernandes, JA Aguilar-Pimentel, MH de Angelis, ... Ageing research reviews 47, 214-277, 2018 | 388 | 2018 |
| miR‐155 modulates microglia‐mediated immune response by down‐regulating SOCS‐1 and promoting cytokine and nitric oxide production AL Cardoso, JR Guedes, L Pereira de Almeida, MC Pedroso de Lima Immunology 135 (1), 73-88, 2012 | 336 | 2012 |
| Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model JR Guedes, CM Custodia, RJ Silva, LP de Almeida, MC Pedroso de Lima, ... Human molecular genetics 23 (23), 6286-6301, 2014 | 172 | 2014 |
| Roles of microglial and monocyte chemokines and their receptors in regulating Alzheimer's disease-associated amyloid-β and tau pathologies JR Guedes, T Lao, AL Cardoso, J El Khoury Frontiers in neurology 9, 381108, 2018 | 116 | 2018 |
| Involvement of microRNA in microglia-mediated immune response J Guedes, ALC Cardoso, MC Pedroso de Lima Journal of Immunology Research 2013, 2013 | 91 | 2013 |
| Glioblastoma hijacks microglial gene expression to support tumor growth SLN Maas, ER Abels, LL Van De Haar, X Zhang, L Morsett, S Sil, ... Journal of neuroinflammation 17, 1-18, 2020 | 87 | 2020 |
| MicroRNA deregulation and chemotaxis and phagocytosis impairment in Alzheimer's disease JR Guedes, I Santana, C Cunha, D Duro, MR Almeida, AM Cardoso, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 3, 7-17, 2016 | 77 | 2016 |
| Role of microRNAs in the regulation of innate immune cells under neuroinflammatory conditions AL Cardoso, JR Guedes, MCP De Lima Current opinion in pharmacology 26, 1-9, 2016 | 76 | 2016 |
| miRNA-31 improves cognition and abolishes amyloid-β pathology by targeting APP and BACE1 in an animal model of Alzheimer’s disease AT Barros-Viegas, V Carmona, E Ferreiro, J Guedes, AM Cardoso, ... Molecular Therapy-Nucleic Acids 19, 1219-1236, 2020 | 70 | 2020 |
| Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant mice M Edfawy, JR Guedes, MI Pereira, M Laranjo, MJ Carvalho, X Gao, ... Nature communications 10 (1), 1431, 2019 | 55 | 2019 |
| The old guard: Age-related changes in microglia and their consequences J Costa, S Martins, PA Ferreira, AMS Cardoso, JR Guedes, J Peça, ... Mechanisms of ageing and development 197, 111512, 2021 | 42 | 2021 |
| Microglia‐dependent remodeling of neuronal circuits JR Guedes, PA Ferreira, JM Costa, AL Cardoso, J Peça Journal of Neurochemistry 163 (2), 74-93, 2022 | 30 | 2022 |
| Recent trends in nanotechnology toward CNS diseases: lipid-based nanoparticles and exosomes for targeted therapeutic delivery AM Cardoso, JR Guedes, AL Cardoso, C Morais, P Cunha, AT Viegas, ... International Review of Neurobiology 130, 1-40, 2016 | 24 | 2016 |
| Social subordination induced by early life adversity rewires inhibitory control of the prefrontal cortex via enhanced Npy1r signaling LO Franco, MJ Carvalho, J Costa, PA Ferreira, JR Guedes, R Sousa, ... Neuropsychopharmacology 45 (9), 1438-1447, 2020 | 15 | 2020 |
| Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications C Rebelo, T Reis, J Guedes, C Saraiva, AF Rodrigues, S Simões, ... Nature Communications 13 (1), 4135, 2022 | 12 | 2022 |
| miRNAs: new biomarkers and therapeutic targets in dementia A Teresa de Barros Viegas, J Ribeiro Guedes, A Rafaela Oliveira, ... Current pharmaceutical design 23 (5), 669-692, 2017 | 11 | 2017 |
| Aberrant hippocampal transmission and behavior in mice with a stargazin mutation linked to intellectual disability GL Caldeira, AS Inácio, N Beltrão, CAV Barreto, MV Rodrigues, T Rondão, ... Molecular Psychiatry 27 (5), 2457-2469, 2022 | 4 | 2022 |
| IL-4 shapes microglia-dependent pruning of the cerebellum during postnatal development JR Guedes, PA Ferreira, J Costa, M Laranjo, MJ Pinto, T Reis, ... Neuron 111 (21), 3435-3449. e8, 2023 | 3 | 2023 |
| Quantifying miRNA deregulation in Alzheimer’s disease AL Cardoso, JR Guedes Biomarkers for Alzheimer’s Disease Drug Development, 307-319, 2018 | 3 | 2018 |
| Microglia: A Double-edged Sword for Alzheimer’s Disease JR Guedes, V AT, P de Lima MC, C AL Microglia: Physiology, Regulation and Health Implications, 1-66, 2015 | 3 | 2015 |
