| Cell protective, ABC triblock polymer-based thermoresponsive hydrogels with ROS-triggered degradation and drug release MK Gupta, JR Martin, TA Werfel, T Shen, JM Page, CL Duvall Journal of the American Chemical Society 136 (42), 14896-14902, 2014 | 259 | 2014 |
| Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers M Miteva, KC Kirkbride, KV Kilchrist, TA Werfel, H Li, CE Nelson, ... Biomaterials 38, 97-107, 2015 | 153 | 2015 |
| Matrix metalloproteinase responsive, proximity‐activated polymeric nanoparticles for siRNA delivery H Li, SS Yu, M Miteva, CE Nelson, T Werfel, TD Giorgio, CL Duvall Advanced functional materials 23 (24), 3040-3052, 2013 | 131 | 2013 |
| Efferocytosis in the tumor microenvironment TA Werfel, RS Cook Seminars in immunopathology 40 (6), 545-554, 2018 | 112 | 2018 |
| Zwitterionic nanocarrier surface chemistry improves siRNA tumor delivery and silencing activity relative to polyethylene glycol MA Jackson, TA Werfel, EJ Curvino, F Yu, TE Kavanaugh, SM Sarett, ... ACS nano 11 (6), 5680-5696, 2017 | 110 | 2017 |
| Lipophilic siRNA targets albumin in situ and promotes bioavailability, tumor penetration, and carrier-free gene silencing SM Sarett, TA Werfel, L Lee, MA Jackson, KV Kilchrist, D Brantley-Sieders, ... Proceedings of the National Academy of Sciences 114 (32), E6490-E6497, 2017 | 108 | 2017 |
| Gal8 visualization of endosome disruption predicts carrier-mediated biologic drug intracellular bioavailability KV Kilchrist, SC Dimobi, MA Jackson, BC Evans, TA Werfel, EA Dailing, ... ACS nano 13 (2), 1136-1152, 2019 | 104 | 2019 |
| Particle-based technologies for osteoarthritis detection and therapy TE Kavanaugh, TA Werfel, H Cho, KA Hasty, CL Duvall Drug delivery and translational research 6, 132-147, 2016 | 77 | 2016 |
| Selective mTORC2 inhibitor therapeutically blocks breast cancer cell growth and survival TA Werfel, S Wang, MA Jackson, TE Kavanaugh, MM Joly, LH Lee, ... Cancer research 78 (7), 1845-1858, 2018 | 75 | 2018 |
| Treatment-induced tumor cell apoptosis and secondary necrosis drive tumor progression in the residual tumor microenvironment through MerTK and IDO1 TA Werfel, DL Elion, B Rahman, DJ Hicks, V Sanchez, ... Cancer research 79 (1), 171-182, 2019 | 66 | 2019 |
| Combinatorial optimization of PEG architecture and hydrophobic content improves ternary siRNA polyplex stability, pharmacokinetics, and potency in vivo TA Werfel, MA Jackson, TE Kavanaugh, KC Kirkbride, M Miteva, ... Journal of Controlled Release 255, 12-26, 2017 | 59 | 2017 |
| Porous silicon and polymer nanocomposites for delivery of peptide nucleic acids as anti-microRNA therapies KR Beavers, TA Werfel, T Shen, TE Kavanaugh, KV Kilchrist, JW Mares, ... Advanced Materials (Deerfield Beach, Fla.) 28 (36), 7984, 2016 | 56 | 2016 |
| Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene … SM Sarett, TA Werfel, I Chandra, MA Jackson, TE Kavanaugh, ... Biomaterials 97, 122-132, 2016 | 52 | 2016 |
| Fluorocoxib A loaded nanoparticles enable targeted visualization of cyclooxygenase-2 in inflammation and cancer MJ Uddin, TA Werfel, BC Crews, MK Gupta, TE Kavanaugh, PJ Kingsley, ... Biomaterials 92, 71-80, 2016 | 42 | 2016 |
| Enhanced performance of plasmid DNA polyplexes stabilized by a combination of core hydrophobicity and surface PEGylation EJ Adolph, CE Nelson, TA Werfel, R Guo, JM Davidson, SA Guelcher, ... Journal of materials chemistry B 2 (46), 8154-8164, 2014 | 42 | 2014 |
| Systemic delivery of a Gli inhibitor via polymeric nanocarriers inhibits tumor-induced bone disease JP Vanderburgh, KA Kwakwa, TA Werfel, AR Merkel, MK Gupta, ... Journal of controlled release 311, 257-272, 2019 | 29 | 2019 |
| Future nanomedicine for the diagnosis and treatment of osteoarthritis LR Eichaker, H Cho, CL Duvall, TA Werfel, KA Hasty Nanomedicine 9 (14), 2203-2215, 2014 | 26 | 2014 |
| Intrinsic apoptotic pathway activation increases response to anti-estrogens in luminal breast cancers MM Williams, L Lee, T Werfel, MMM Joly, DJ Hicks, B Rahman, D Elion, ... Cell Death & Disease 9 (2), 21, 2018 | 24 | 2018 |
| Improved nanoformulation and bio-functionalization of linear-dendritic block copolymers with biocompatible ionic liquids CM Hamadani, I Chandrasiri, ML Yaddehige, GS Dasanayake, I Owolabi, ... Nanoscale 14 (16), 6021-6036, 2022 | 17 | 2022 |
| Repurposing of a thromboxane receptor inhibitor based on a novel role in metastasis identified by phenome-wide association study TA Werfel, DJ Hicks, B Rahman, WE Bendeman, MT Duvernay, JG Maeng, ... Molecular cancer therapeutics 19 (12), 2454-2464, 2020 | 14 | 2020 |
