New free-exchange model of EmrE transport AE Robinson, NE Thomas, EA Morrison, BM Balthazor, ... Proceedings of the National Academy of Sciences 114 (47), E10083-E10091, 2017 | 56 | 2017 |
Structure and dynamics of the drug-bound bacterial transporter EmrE in lipid bilayers AA Shcherbakov, G Hisao, VS Mandala, NE Thomas, M Soltani, EA Salter, ... Nature Communications 12 (1), 172, 2021 | 45 | 2021 |
Highly coupled transport can be achieved in free-exchange transport models GA Hussey, NE Thomas, KA Henzler-Wildman Journal of General Physiology 152 (1), e201912437, 2019 | 27 | 2019 |
Identification of an alternating-access dynamics mutant of EmrE with impaired transport C Wu, SA Wynne, NE Thomas, EM Uhlemann, CG Tate, ... Journal of molecular biology 431 (15), 2777-2789, 2019 | 20 | 2019 |
The C terminus of the bacterial multidrug transporter EmrE couples drug binding to proton release NE Thomas, C Wu, EA Morrison, AE Robinson, JP Werner, ... Journal of Biological Chemistry 293 (49), 19137-19147, 2018 | 18 | 2018 |
Estimates of RelSeq, Mesh1, and SAHMex hydrolysis of (p) ppGpp and (p) ppApp by thin layer chromatography and NADP/NADH coupled assays K Potrykus, NE Thomas, B Bruhn-Olszewska, M Sobala, M Dylewski, ... Frontiers in Microbiology 11, 581271, 2020 | 15 | 2020 |
A solid-supported membrane electrophysiology assay for efficient characterization of ion-coupled transport NE Thomas, W Feng, KA Henzler-Wildman Journal of Biological Chemistry 297 (4), 2021 | 12 | 2021 |
Activating alternative transport modes in a multidrug resistance efflux pump to confer chemical susceptibility PJ Spreacker, NE Thomas, WF Beeninga, M Brousseau, CJ Porter, ... Nature Communications 13 (1), 7655, 2022 | 6 | 2022 |
Proceedings of the National Academy of Sciences of the United States of America CK Johnson, LG Tassinary | 2 | 2007 |
A new substrate triggers susceptibility by uncoupling a bacterial multidrug resistance efflux pump PJ Spreacker, NE Thomas, WF Beeninga, M Brousseau, KM Hibbs, ... bioRxiv, 2021.12. 04.471113, 2021 | 1 | 2021 |
Unlocking the reversal potential of solid supported membrane electrophysiology to determine transport stoichiometry NE Thomas, KA Henzler-Wildman bioRxiv, 2020.05. 07.082438, 2020 | 1 | 2020 |
A kinetically-driven free exchange mechanism of EmrE antiport sacrifices coupling efficiency in favor of promiscuity AE Robinson, NE Thomas, EA Morrison, B Balthazor, ... bioRxiv, 141937, 2017 | 1 | 2017 |
Using solid-supported membrane electrophysiology to probe the transport mechanism of EmrE M Brousseau, NE Thomas, PJ Spreacker, KA Henzler-Wildman Biophysical Journal 122 (3), 400a, 2023 | | 2023 |
Can Complete Transporter Mechanisms be Inferred from Experimental Data? A George, NE Thomas, KA Henzler-Wildman, DM Zuckerman Biophysical Journal 120 (3), 85a, 2021 | | 2021 |
The Proton/Drug Coupling Mechanism of EmrE NE Thomas The University of Wisconsin-Madison, 2021 | | 2021 |
Rethinking the Bounds of Ion-Coupled Transport NE Thomas, G Hussey, KA Henzler-Wildman Biophysical Journal 118 (3), 130a, 2020 | | 2020 |
Controlling the Rate and Efficiency of Proton-Coupled Transport by EmrE N Thomas, C Wu, P Spreacker, G Hussey, S Wynne, EM Uhlemann, ... Biophysical Journal 118 (3), 2a, 2020 | | 2020 |
A free‐exchange mathematical model of EmrE G Hussey, N Thomas, K Henzler‐Wildman The FASEB Journal 33 (S1), 656.6-656.6, 2019 | | 2019 |
Sacrificing efficiency to achieve promiscuity: re-examining the multi drug transport mechanism of EmrE K Henzler-Wildman, A Robinson, N Thomas, E Morrison FEBS JOURNAL 284, 15-15, 2017 | | 2017 |
Determination of EmrE’s Proton/Drug Coupling Stoichiometry N Thomas, K Henzler-Wildman | | |