| International patterns and trends in thyroid cancer incidence, 1973–2002 BA Kilfoy, T Zheng, TR Holford, X Han, MH Ward, A Sjodin, Y Zhang, ... Cancer causes & control 20, 525-531, 2009 | 937 | 2009 |
| Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine I Kim, SH Ahn, T Inagaki, M Choi, S Ito, GL Guo, SA Kliewer, FJ Gonzalez Journal of lipid research 48 (12), 2664-2672, 2007 | 603 | 2007 |
| The farnesoid X-receptor is an essential regulator of cholesterol homeostasis G Lambert, MJA Amar, G Guo, HB Brewer, FJ Gonzalez, CJ Sinal Journal of Biological Chemistry 278 (4), 2563-2570, 2003 | 481 | 2003 |
| Mechanism of tissue‐specific farnesoid X receptor in suppressing the expression of genes in bile‐acid synthesis in mice B Kong, L Wang, JYL Chiang, Y Zhang, CD Klaassen, GL Guo Hepatology 56 (3), 1034-1043, 2012 | 416 | 2012 |
| Oxidative and electrophilic stress induces multidrug resistance–associated protein transporters via the nuclear factor‐E2–related factor‐2 transcriptional pathway JM Maher, MZ Dieter, LM Aleksunes, AL Slitt, G Guo, Y Tanaka, ... Hepatology 46 (5), 1597-1610, 2007 | 372 | 2007 |
| Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity GL Guo, G Lambert, M Negishi, JM Ward, HB Brewer, SA Kliewer, ... Journal of Biological Chemistry 278 (46), 45062-45071, 2003 | 363 | 2003 |
| Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice M Wagner, P Fickert, G Zollner, A Fuchsbichler, D Silbert, O Tsybrovskyy, ... Gastroenterology 125 (3), 825-838, 2003 | 301 | 2003 |
| NF-E2-related factor 2 inhibits lipid accumulation and oxidative stress in mice fed a high-fat diet Y Tanaka, LM Aleksunes, RL Yeager, MA Gyamfi, N Esterly, GL Guo, ... Journal of Pharmacology and Experimental Therapeutics 325 (2), 655-664, 2008 | 270 | 2008 |
| Overexpression of cholesterol 7α‐hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis T Li, M Matozel, S Boehme, B Kong, LM Nilsson, G Guo, E Ellis, ... Hepatology 53 (3), 996-1006, 2011 | 247 | 2011 |
| Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development RRM Maran, A Thomas, M Roth, Z Sheng, N Esterly, D Pinson, X Gao, ... Journal of Pharmacology and Experimental Therapeutics 328 (2), 469-477, 2009 | 246 | 2009 |
| Farnesoid X receptor deficiency induces nonalcoholic steatohepatitis in low-density lipoprotein receptor-knockout mice fed a high-fat diet B Kong, JP Luyendyk, O Tawfik, GL Guo Journal of Pharmacology and Experimental Therapeutics 328 (1), 116-122, 2009 | 228 | 2009 |
| Estrogen receptor α mediates 17α-ethynylestradiol causing hepatotoxicity Y Yamamoto, R Moore, HA Hess, GL Guo, FJ Gonzalez, KS Korach, ... Journal of Biological Chemistry 281 (24), 16625-16631, 2006 | 212 | 2006 |
| Genome‐wide tissue‐specific farnesoid X receptor binding in mouse liver and intestine AM Thomas, SN Hart, B Kong, J Fang, X Zhong, GL Guo Hepatology 51 (4), 1410-1419, 2010 | 210 | 2010 |
| Orally administered berberine modulates hepatic lipid metabolism by altering microbial bile acid metabolism and the intestinal FXR signaling pathway R Sun, N Yang, B Kong, B Cao, D Feng, X Yu, C Ge, J Huang, J Shen, ... Molecular pharmacology 91 (2), 110-122, 2017 | 170 | 2017 |
| The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators EK Pacyniak, X Cheng, ML Cunningham, K Crofton, CD Klaassen, ... Toxicological Sciences 97 (1), 94-102, 2007 | 166 | 2007 |
| Protective role of hydroxysteroid sulfotransferase in lithocholic acid-induced liver toxicity H Kitada, M Miyata, T Nakamura, A Tozawa, W Honma, M Shimada, ... Journal of Biological Chemistry 278 (20), 17838-17844, 2003 | 166 | 2003 |
| Induction of rat organic anion transporting polypeptide 2 by pregnenolone-16α-carbonitrile is via interaction with pregnane X receptor GL Guo, J Staudinger, K Ogura, CD Klaassen Molecular pharmacology 61 (4), 832-839, 2002 | 161 | 2002 |
| Rifaximin is a gut-specific human pregnane X receptor activator X Ma, YM Shah, GL Guo, T Wang, KW Krausz, JR Idle, FJ Gonzalez Journal of Pharmacology and Experimental Therapeutics 322 (1), 391-398, 2007 | 157 | 2007 |
| The PREgnane X receptor gene-humanized mouse: a model for investigating drug-drug interactions mediated by cytochromes P450 3A X Ma, Y Shah, C Cheung, GL Guo, L Feigenbaum, KW Krausz, JR Idle, ... Drug metabolism and disposition 35 (2), 194-200, 2007 | 151 | 2007 |
| Effects of FXR in foam-cell formation and atherosclerosis development GL Guo, S Santamarina-Fojo, TE Akiyama, MJA Amar, BJ Paigen, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2006 | 150 | 2006 |
