| The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus B Chabot, DA Stephenson, VM Chapman, P Besmer, A Bernstein Nature 335 (6185), 88-89, 1988 | 1778 | 1988 |
| W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity JD Hulzinga, L Thuneberg, M Klüppel, J Malysz, HB Mikkelsen, ... Nature 373 (6512), 347-349, 1995 | 1673 | 1995 |
| A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis F Shalaby, J Ho, WL Stanford, KD Fischer, AC Schuh, L Schwartz, ... Cell 89 (6), 981-990, 1997 | 1193 | 1997 |
| Grand challenges in chronic non-communicable diseases AS Daar, PA Singer, D Leah Persad, SK Pramming, DR Matthews, ... Nature 450 (7169), 494-496, 2007 | 901 | 2007 |
| Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells S Hitoshi, T Alexson, V Tropepe, D Donoviel, AJ Elia, JS Nye, RA Conlon, ... Genes & development 16 (7), 846-858, 2002 | 847 | 2002 |
| p53 mutations increase resistance to ionizing radiation. JM Lee, A Bernstein Proceedings of the National Academy of Sciences 90 (12), 5742-5746, 1993 | 831 | 1993 |
| Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/Wv mice JE Dick, MC Magli, D Huszar, RA Phillips, A Bernstein Cell 42 (1), 71-79, 1985 | 820 | 1985 |
| The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells. MC Puri, J Rossant, K Alitalo, A Bernstein, J Partanen The EMBO journal 14 (23), 5884-5891, 1995 | 639 | 1995 |
| Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice. K Nocka, S Majumder, B Chabot, P Ray, M Cervone, A Bernstein, ... Genes & development 3 (6), 816-826, 1989 | 610 | 1989 |
| Mice lacking both presenilin genes exhibitearlyembryonic patterningdefects DB Donoviel, AK Hadjantonakis, M Ikeda, H Zheng, PSG Hyslop, ... Genes & development 13 (21), 2801-2810, 1999 | 590 | 1999 |
| Presenilins are required for γ-secretase cleavage of β-APP and transmembrane cleavage of Notch-1 Z Zhang, P Nadeau, W Song, D Donoviel, M Yuan, A Bernstein, ... Nature cell biology 2 (7), 463-465, 2000 | 528 | 2000 |
| Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor KD Fischer, YY Kong, H Nishina, K Tedford, LEM Marengere, ... Current Biology 8 (10), S1-S3, 1998 | 508 | 1998 |
| High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene A Lavigueur, V Maltby, D Mock, J Rossant, T Pawson, A Bernstein Molecular and cellular biology, 1989 | 499 | 1989 |
| Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1. Y Ben-David, EB Giddens, K Letwin, A Bernstein Genes & development 5 (6), 908-918, 1991 | 481 | 1991 |
| Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus M Mowat, A Cheng, N Kimura, A Bernstein, S Benchimol Nature 314 (6012), 633-636, 1985 | 456 | 1985 |
| Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia A Hart, F Melet, P Grossfeld, K Chien, C Jones, A Tunnacliffe, R Favier, ... Immunity 13 (2), 167-177, 2000 | 437 | 2000 |
| Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3 H Nishina, KD Fischer, L Radvanyi, A Shahinian, R Hakem, EA Rubie, ... Nature 385 (6614), 350-353, 1997 | 437 | 1997 |
| W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor. AD Reith, R Rottapel, E Giddens, C Brady, L Forrester, A Bernstein Genes & development 4 (3), 390-400, 1990 | 372 | 1990 |
| The c-kit receptor ligand functions as a mast cell chemoattractant CJ Meininger, H Yano, R Rottapel, A Bernstein, KM Zsebo, BR Zetter | 368 | 1992 |
| Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+CDS+thymocytes KD Fischer, A Zmuidzinas, S Gardner, M Barbacid, A Bernstein, C Guidos Nature 374 (6521), 474-476, 1995 | 363 | 1995 |
