| HIV-1 Nef sequesters MHC-I intracellularly by targeting early stages of endocytosis and recycling BS Dirk, EN Pawlak, AL Johnson, LR Van Nynatten, RA Jacob, B Heit, ... Scientific reports 6 (1), 37021, 2016 | 75 | 2016 |
| Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses A Banerjee, N El-Sayes, P Budylowski, RA Jacob, D Richard, H Maan, ... IScience 24 (5), 2021 | 46 | 2021 |
| Anti-V3/glycan and anti-MPER neutralizing antibodies, but not anti-V2/glycan site antibodies, are strongly associated with greater anti-HIV-1 neutralization breadth and potency RA Jacob, T Moyo, M Schomaker, F Abrahams, B Grau Pujol, JR Dorfman Journal of virology 89 (10), 5264-5275, 2015 | 41 | 2015 |
| The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4+ T cells EN Pawlak, BS Dirk, RA Jacob, AL Johnson, JD Dikeakos Retrovirology 15, 1-22, 2018 | 32 | 2018 |
| HIV-1 Vpu Downregulates Tim-3 from the Surface of Infected CD4+ T Cells J Prévost, CR Edgar, J Richard, SM Trothen, RA Jacob, MJ Mumby, ... Journal of Virology 94 (7), 10.1128/jvi. 01999-19, 2020 | 31 | 2020 |
| Efferocytic defects in early atherosclerosis are driven by GATA2 overexpression in macrophages C Yin, AM Vrieze, M Rosoga, J Akingbasote, EN Pawlak, RA Jacob, J Hu, ... Frontiers in immunology 11, 594136, 2020 | 28 | 2020 |
| The interaction between HIV-1 Nef and adaptor protein-2 reduces Nef-mediated CD4+ T cell apoptosis RA Jacob, AL Johnson, EN Pawlak, BS Dirk, LR Van Nynatten, ... Virology 509, 1-10, 2017 | 22 | 2017 |
| Viral bimolecular fluorescence complementation: a novel tool to study intracellular vesicular trafficking pathways BS Dirk, RA Jacob, AL Johnson, EN Pawlak, PC Cavanagh, ... PLoS One 10 (4), e0125619, 2015 | 19 | 2015 |
| Molecular basis of unusually high neutralization resistance in tier 3 HIV-1 strain 253-11 T Moyo, J Ereño-Orbea, RA Jacob, CE Pavillet, SM Kariuki, EN Tangie, ... Journal of Virology 92 (14), 10.1128/jvi. 02261-17, 2018 | 18 | 2018 |
| HIV-1 Tat-specific IgG antibodies in high-responders target a B-cell epitope in the cysteine-rich domain and block extracellular Tat efficiently VP Kashi, RA Jacob, S Paul, K Nayak, B Satish, S Swaminathan, ... Vaccine 27 (48), 6739-6747, 2009 | 15 | 2009 |
| The HIV-1 accessory protein Nef increases surface expression of the checkpoint receptor Tim-3 in infected CD4+ T cells RA Jacob, CR Edgar, JÚÚ PrÚvost, SM Trothen, A Lurie, MJ Mumby, ... Journal of Biological Chemistry 297 (3), 2021 | 14 | 2021 |
| Refined identification of neutralization-resistant HIV-1 CRF02_AG viruses RA Jacob, F Abrahams, M Tongo, M Schomaker, P Roux, E Mpoudi Ngole, ... Journal of virology 86 (14), 7699-7703, 2012 | 13 | 2012 |
| The grafting of universal T-helper epitopes enhances immunogenicity of HIV-1 Tat concurrently improving its safety profile VP Kashi, RA Jacob, RA Shamanna, M Menon, A Balasiddaiah, ... PloS one 9 (12), e114155, 2014 | 11 | 2014 |
| Discovery and use of long dsRNA mediated RNA interference to stimulate antiviral protection in interferon competent Mammalian cells SL Semple, SKW Au, RA Jacob, KL Mossman, SJ DeWitte-Orr Frontiers in Immunology 13, 859749, 2022 | 7 | 2022 |
| Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses. iScience. 2021; 24: 102477 A Banerjee, N El-Sayes, P Budylowski, RA Jacob, D Richard, H Maan, ... PubMed https://doi. org/10.1016/j. isci, 2021 | 5 | 2021 |
| Altered microRNA transcriptome in cultured human airway cells upon infection with SARS-CoV-2 I Diallo, RA Jacob, E Vion, RA Kozak, K Mossman, P Provost Viruses 15 (2), 496, 2023 | 4 | 2023 |
| PACS-1 and adaptor protein-1 mediate ACTH trafficking to the regulated secretory pathway BS Dirk, C End, EN Pawlak, LR Van Nynatten, RA Jacob, B Heit, ... Biochemical and biophysical research communications 507 (1-4), 519-525, 2018 | 4 | 2018 |
| Lower anti-HIV-1 neutralization in HIV-infected children with CD4+ T cell depletion: opposite correlation to that in adults M Agthe, E Nemes, RA Jacob, F Abrahams, N Fainguem, SMN Tetang, ... Aids 28 (11), 1694-1696, 2014 | 3 | 2014 |
| ASK1 inhibitors are potential pan-antiviral drugs, which dampen replication of diverse viruses including SARS-CoV2 WL Demian, RA Jacob, O Cormier, A Nazli, M Melki, A Asavajaru, K Baid, ... Antiviral Research 220, 105736, 2023 | 2 | 2023 |
| Evaluating the neutralizing antibody response to HIV-1 membrane proximal external regional; Implications for vaccine design RA Jacob | 2 | 2014 |
