ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models PE Cramer, JR Cirrito, DW Wesson, CYD Lee, JC Karlo, AE Zinn, ... science 335 (6075), 1503-1506, 2012 | 1236 | 2012 |
ApoE promotes the proteolytic degradation of Aβ Q Jiang, CYD Lee, S Mandrekar, B Wilkinson, P Cramer, N Zelcer, ... Neuron 58 (5), 681-693, 2008 | 1109 | 2008 |
The role of microglia in amyloid clearance from the AD brain CYD Lee, GE Landreth Journal of neural transmission 117, 949-960, 2010 | 736 | 2010 |
Microglia mediate the clearance of soluble Aβ through fluid phase macropinocytosis S Mandrekar, Q Jiang, CYD Lee, J Koenigsknecht-Talboo, DM Holtzman, ... Journal of Neuroscience 29 (13), 4252-4262, 2009 | 476 | 2009 |
Steroid regulation of autophagic programmed cell death during development CY Lee, EH Baehrecke Development 128 (8), 1443-1455, 2001 | 398 | 2001 |
Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation CY Lee, KJ Robinson, CQ Doe Nature 439 (7076), 594-598, 2006 | 375 | 2006 |
Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal CY Lee, BD Wilkinson, SE Siegrist, RP Wharton, CQ Doe Developmental cell 10 (4), 441-449, 2006 | 370 | 2006 |
Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia MM Rolls, R Albertson, HP Shih, CY Lee, CQ Doe The Journal of cell biology 163 (5), 1089-1098, 2003 | 332 | 2003 |
Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation CY Lee, RO Andersen, C Cabernard, L Manning, KD Tran, MJ Lanskey, ... Genes & development 20 (24), 3464-3474, 2006 | 297 | 2006 |
Genome-wide analyses of steroid-and radiation-triggered programmed cell death in Drosophila CY Lee, EA Clough, P Yellon, TM Teslovich, DA Stephan, EH Baehrecke Current Biology 13 (4), 350-357, 2003 | 265 | 2003 |
Steroid regulation of midgut cell death during Drosophila development CY Lee, BAK Cooksey, EH Baehrecke Developmental biology 250 (1), 101-111, 2002 | 243 | 2002 |
E93 directs steroid-triggered programmed cell death in Drosophila CY Lee, DP Wendel, P Reid, G Lam, CS Thummel, EH Baehrecke Molecular cell 6 (2), 433-443, 2000 | 215 | 2000 |
Apolipoprotein E promotes β-amyloid trafficking and degradation by modulating microglial cholesterol levels CYD Lee, W Tse, JD Smith, GE Landreth Journal of Biological Chemistry 287 (3), 2032-2044, 2012 | 200 | 2012 |
Regulation of microglial phagocytosis and inflammatory gene expression by Gas6 acting on the Axl/Mer family of tyrosine kinases C Grommes, CYD Lee, BL Wilkinson, Q Jiang, JL Koenigsknecht-Talboo, ... Journal of neuroimmune pharmacology 3, 130-140, 2008 | 170 | 2008 |
dFezf/Earmuff maintains the restricted developmental potential of intermediate neural progenitors in Drosophila M Weng, KL Golden, CY Lee Developmental cell 18 (1), 126-135, 2010 | 161 | 2010 |
Fibrillar β-amyloid-stimulated intracellular signaling cascades require Vav for induction of respiratory burst and phagocytosis in monocytes and microglia B Wilkinson, J Koenigsknecht-Talboo, C Grommes, CYD Lee, G Landreth Journal of Biological Chemistry 281 (30), 20842-20850, 2006 | 158 | 2006 |
Genetic mechanism for the stage-and tissue-specific regulation of steroid triggered programmed cell death in Drosophila CY Lee, CR Simon, CT Woodard, EH Baehrecke Developmental biology 252 (1), 138-148, 2002 | 126 | 2002 |
RBPJ/CBF 1 interacts with L3 MBTL 3/MBT 1 to promote repression of Notch signaling via histone demethylase KDM 1A/LSD 1 T Xu, SS Park, BD Giaimo, D Hall, F Ferrante, DM Ho, K Hori, L Anhezini, ... The EMBO journal 36 (21), 3232-3249, 2017 | 62 | 2017 |
Earmuff restricts progenitor cell potential by attenuating the competence to respond to self-renewal factors DH Janssens, H Komori, D Grbac, K Chen, CT Koe, H Wang, CY Lee Development 141 (5), 1036-1046, 2014 | 57 | 2014 |
klumpfuss distinguishes stem cells from progenitor cells during asymmetric neuroblast division Q Xiao, H Komori, CY Lee Development 139 (15), 2670-2680, 2012 | 54 | 2012 |