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Marcello Leopoldo
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Serotonin 5-HT7 receptor agents: structure-activity relationships and potential therapeutic applications in central nervous system disorders
M Leopoldo, E Lacivita, F Berardi, R Perrone, PB Hedlund
Pharmacology & therapeutics 129 (2), 120-148, 2011
2202011
International Union of Basic and Clinical Pharmacology. CX. Classification of receptors for 5-hydroxytryptamine; pharmacology and function
NM Barnes, GP Ahern, C Becamel, J Bockaert, M Camilleri, ...
Pharmacological reviews 73 (1), 310-520, 2021
1572021
Interplay between Serotonin 5‐HT1A and 5‐HT7 Receptors in Depressive Disorders
VS Naumenko, NK Popova, E Lacivita, M Leopoldo, EG Ponimaskin
CNS neuroscience & therapeutics 20 (7), 582-590, 2014
1482014
Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome
L Costa, M Spatuzza, S D'Antoni, CM Bonaccorso, C Trovato, ...
Biological psychiatry 72 (11), 924-933, 2012
1352012
Developments in fluorescent probes for receptor research
M Leopoldo, E Lacivita, F Berardi, R Perrone
Drug discovery today 14 (13-14), 706-712, 2009
1052009
Structure−Affinity Relationship Study on N-[4-(4-Arylpiperazin-1-yl)butyl]arylcarboxamides as Potent and Selective Dopamine D3 Receptor Ligands
M Leopoldo, F Berardi, NA Colabufo, P De Giorgio, E Lacivita, R Perrone, ...
Journal of medicinal chemistry 45 (26), 5727-5735, 2002
1042002
High affinity and selectivity on 5-HT1A receptor of 1-aryl-4-[(1-tetralin) alkyl] piperazines. 2
R Perrone, F Berardi, NA Colabufo, M Leopoldo, V Tortorella, F Fiorentini, ...
Journal of medicinal chemistry 38 (6), 942-949, 1995
1031995
Small and innovative molecules as new strategy to revert MDR
L Zinzi, E Capparelli, M Cantore, M Contino, M Leopoldo, NA Colabufo
Frontiers in oncology 4, 2, 2014
1002014
5-HT1A receptor, an old target for new therapeutic agents
E Lacivita, M Leopoldo, F Berardi, R Perrone
Current Topics in Medicinal Chemistry 8 (12), 1024-1034, 2008
992008
Structural Modifications of N-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4-Aryl-1-piperazinehexanamides: Influence on Lipophilicity and 5-HT7 Receptor Activity. Part III
M Leopoldo, E Lacivita, P De Giorgio, C Fracasso, S Guzzetti, S Caccia, ...
Journal of medicinal chemistry 51 (18), 5813-5822, 2008
902008
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT7 receptor
PB Hedlund, M Leopoldo, S Caccia, G Sarkisyan, C Fracasso, G Martelli, ...
Neuroscience letters 481 (1), 12-16, 2010
872010
Serotonin7 receptors (5-HT7Rs) and their ligands
M Leopoldo
Current medicinal chemistry 11 (5), 629-661, 2004
862004
Serotonin 5‐HT 7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons
L Speranza, J Labus, F Volpicelli, D Guseva, E Lacivita, M Leopoldo, ...
Journal of Neurochemistry 141 (5), 647-661, 2017
832017
Structure−Affinity Relationship Study on N-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4-Aryl-1-Piperazinealkylamides, a New Class of 5-Hydroxytryptamine7 Receptor …
M Leopoldo, F Berardi, NA Colabufo, M Contino, E Lacivita, M Niso, ...
Journal of medicinal chemistry 47 (26), 6616-6624, 2004
832004
Pharmacological stimulation of the brain serotonin receptor 7 as a novel therapeutic approach for Rett syndrome
B De Filippis, P Nativio, A Fabbri, L Ricceri, W Adriani, E Lacivita, ...
Neuropsychopharmacology 39 (11), 2506-2518, 2014
802014
Structure−Activity Relationship Study on N-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a Class of 5-HT7 Receptor Agents. 2
M Leopoldo, E Lacivita, M Contino, NA Colabufo, F Berardi, R Perrone
Journal of medicinal chemistry 50 (17), 4214-4221, 2007
772007
The serotonin receptor 7 promotes neurite outgrowth via ERK and Cdk5 signaling pathways
L Speranza, A Chambery, M Di Domenico, M Crispino, V Severino, ...
Neuropharmacology 67, 155-167, 2013
762013
Modulatory effects of two novel agonists for serotonin receptor 7 on emotion, motivation and circadian rhythm profiles in mice
W Adriani, D Travaglini, E Lacivita, L Saso, M Leopoldo, G Laviola
Neuropharmacology 62 (2), 833-842, 2012
722012
Synthesis and Structure−Affinity Relationships of 1-[ω-(4-Aryl-1-piperazinyl)alkyl]-1-aryl Ketones as 5-HT7 Receptor Ligands
R Perrone, F Berardi, NA Colabufo, E Lacivita, M Leopoldo, V Tortorella
Journal of medicinal chemistry 46 (4), 646-649, 2003
722003
ABC transporters in CSCs membranes as a novel target for treating tumor relapse
L Zinzi, M Contino, M Cantore, E Capparelli, M Leopoldo, NA Colabufo
Frontiers in Pharmacology 5, 92901, 2014
712014
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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