CD4+ T cell help is required for the formation of a cytolytic CD8+ T cell subset that protects against chronic infection and cancer R Zander, D Schauder, G Xin, C Nguyen, X Wu, A Zajac, W Cui Immunity 51 (6), 1028-1042. e4, 2019 | 473 | 2019 |
Transcriptional and epigenetic regulation of effector and memory CD8 T cell differentiation Y Chen, R Zander, A Khatun, DM Schauder, W Cui Frontiers in immunology 9, 2826, 2018 | 151 | 2018 |
PD-1 co-inhibitory and OX40 co-stimulatory crosstalk regulates helper T cell differentiation and anti-Plasmodium humoral immunity RA Zander, N Obeng-Adjei, JJ Guthmiller, DI Kulu, J Li, A Ongoiba, ... Cell host & microbe 17 (5), 628-641, 2015 | 107 | 2015 |
BATF regulates progenitor to cytolytic effector CD8+ T cell transition during chronic viral infection Y Chen, RA Zander, X Wu, DM Schauder, MY Kasmani, J Shen, S Zheng, ... Nature immunology 22 (8), 996-1007, 2021 | 89 | 2021 |
Single-cell RNA sequencing unveils an IL-10-producing helper subset that sustains humoral immunity during persistent infection G Xin, R Zander, DM Schauder, Y Chen, JS Weinstein, WR Drobyski, ... Nature communications 9 (1), 5037, 2018 | 88 | 2018 |
Cutting edge: IL-10 is essential for the generation of germinal center B cell responses and anti-plasmodium humoral immunity JJ Guthmiller, AC Graham, RA Zander, RL Pope, NS Butler The Journal of Immunology 198 (2), 617-622, 2017 | 87 | 2017 |
Type I interferons induce T regulatory 1 responses and restrict humoral immunity during experimental malaria RA Zander, JJ Guthmiller, AC Graham, RL Pope, BE Burke, DJJ Carr, ... PLoS pathogens 12 (10), e1005945, 2016 | 68 | 2016 |
Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection R Zander, MY Kasmani, Y Chen, P Topchyan, J Shen, S Zheng, R Burns, ... Immunity 55 (3), 475-493. e5, 2022 | 58 | 2022 |
Th1-like plasmodium-specific memory CD4+ T cells support humoral immunity RA Zander, R Vijay, AD Pack, JJ Guthmiller, AC Graham, SE Lindner, ... Cell reports 21 (7), 1839-1852, 2017 | 57 | 2017 |
Single-cell lineage mapping of a diverse virus-specific naive CD4 T cell repertoire A Khatun, MY Kasmani, R Zander, DM Schauder, JP Snook, J Shen, X Wu, ... Journal of Experimental Medicine 218 (3), 2021 | 49 | 2021 |
Potent inhibition of tumour cell proliferation and immunoregulatory function by mitochondria-targeted atovaquone G Cheng, M Hardy, P Topchyan, R Zander, P Volberding, W Cui, ... Scientific reports 10 (1), 17872, 2020 | 37 | 2020 |
Clonal lineage tracing reveals mechanisms skewing CD8+ T cell fate decisions in chronic infection MY Kasmani, R Zander, HK Chung, Y Chen, A Khatun, M Damo, ... Journal of Experimental Medicine 220 (1), e20220679, 2022 | 29 | 2022 |
Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function M Langer, ES Duggan, JL Booth, VI Patel, RA Zander, R Silasi-Mansat, ... Infection and immunity 80 (12), 4374-4387, 2012 | 27 | 2012 |
BATF promotes group 2 innate lymphoid cell–mediated lung tissue protection during acute respiratory virus infection X Wu, MY Kasmani, S Zheng, A Khatun, Y Chen, W Winkler, R Zander, ... Science immunology 7 (67), eabc9934, 2022 | 25 | 2022 |
Dysfunctional adaptive immunity during parasitic infections R A Zander, N S Butler Current immunology reviews 9 (3), 179-189, 2013 | 21 | 2013 |
Pathogen-boosted adoptive cell transfer therapy induces endogenous antitumor immunity through antigen spreading G Xin, A Khatun, P Topchyan, R Zander, PJ Volberding, Y Chen, J Shen, ... Cancer immunology research 8 (1), 7-18, 2020 | 20 | 2020 |
Mitochondria-targeted hydroxyurea inhibits OXPHOS and induces antiproliferative and immunomodulatory effects G Cheng, M Hardy, P Topchyan, R Zander, P Volberding, W Cui, ... Iscience 24 (6), 2021 | 17 | 2021 |
Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity FA Surette, JJ Guthmiller, L Li, AJ Sturtz, R Vijay, RL Pope, BL McClellan, ... PLoS pathogens 17 (2), e1009288, 2021 | 17 | 2021 |
Delineating the transcriptional landscape and clonal diversity of virus-specific CD4+ T cells during chronic viral infection R Zander, A Khatun, MY Kasmani, Y Chen, W Cui Elife 11, e80079, 2022 | 10 | 2022 |
Exhausted CD8+ T cells face a developmental fork in the road R Zander, W Cui Trends in Immunology, 2023 | 9 | 2023 |