Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities RC Samaco, C Mandel-Brehm, HT Chao, CS Ward, SL Fyffe-Maricich, ... Proceedings of the National Academy of Sciences 106 (51), 21966-21971, 2009 | 278 | 2009 |
rRNA promoter regulation by nonoptimal binding of σ region 1.2: an additional recognition element for RNA polymerase SP Haugen, MB Berkmen, W Ross, T Gaal, C Ward, RL Gourse Cell 125 (6), 1069-1082, 2006 | 269 | 2006 |
Female Mecp2+/− mice display robust behavioral deficits on two different genetic backgrounds providing a framework for pre-clinical studies RC Samaco, CM McGraw, CS Ward, Y Sun, JL Neul, HY Zoghbi Human molecular genetics 22 (1), 96-109, 2013 | 190 | 2013 |
Breathing challenges in Rett syndrome: lessons learned from humans and animal models JM Ramirez, CS Ward, JL Neul Respiratory physiology & neurobiology 189 (2), 280-287, 2013 | 147 | 2013 |
Effects of sublethal UVA irradiation on activity levels of oxidative defense enzymes and protein oxidation in Escherichia coli JD Hoerter, AA Arnold, DA Kuczynska, A Shibuya, CS Ward, MG Sauer, ... Journal of Photochemistry and Photobiology B: Biology 81 (3), 171-180, 2005 | 113 | 2005 |
Pathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: implication for therapy in Rett syndrome MD McCauley, T Wang, E Mike, J Herrera, DL Beavers, TW Huang, ... Science translational medicine 3 (113), 113ra125-113ra125, 2011 | 92 | 2011 |
MeCP2 is critical within HoxB1-derived tissues of mice for normal lifespan CS Ward, EM Arvide, TW Huang, J Yoo, JL Noebels, JL Neul Journal of Neuroscience 31 (28), 10359-10370, 2011 | 87 | 2011 |
Somatic gain of KRAS function in the endothelium is sufficient to cause vascular malformations that require MEK but not PI3K signaling JE Fish, CP Flores Suarez, E Boudreau, AM Herman, MC Gutierrez, ... Circulation research 127 (6), 727-743, 2020 | 84 | 2020 |
Overexpression of methyl-CpG binding protein 2 impairs TH1 responses T Yang, MB Ramocki, JL Neul, W Lu, L Roberts, J Knight, CS Ward, ... Science translational medicine 4 (163), 163ra158-163ra158, 2012 | 75 | 2012 |
Regional rescue of spinocerebellar ataxia type 1 phenotypes by 14-3-3ε haploinsufficiency in mice underscores complex pathogenicity in neurodegeneration P Jafar-Nejad, CS Ward, R Richman, HT Orr, HY Zoghbi Proceedings of the National Academy of Sciences 108 (5), 2142-2147, 2011 | 73 | 2011 |
Respiratory network stability and modulatory response to substance P require Nalcn SY Yeh, WH Huang, W Wang, CS Ward, ES Chao, Z Wu, B Tang, J Tang, ... Neuron 94 (2), 294-303. e4, 2017 | 61 | 2017 |
Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome S Veeraragavan, YW Wan, DR Connolly, SM Hamilton, CS Ward, ... Human molecular genetics 25 (15), 3284-3302, 2016 | 59 | 2016 |
Atoh1 governs the migration of postmitotic neurons that shape respiratory effectiveness at birth and chemoresponsiveness in adulthood WH Huang, S Tupal, TW Huang, CS Ward, JL Neul, TJ Klisch, PA Gray, ... Neuron 75 (5), 799-809, 2012 | 56 | 2012 |
Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function MR Pitcher, CS Ward, EM Arvide, CA Chapleau, L Pozzo-Miller, ... Human molecular genetics 22 (13), 2626-2633, 2013 | 47 | 2013 |
Reduced hydroperoxidase (HPI and HPII) activity in the Δfur mutant contributes to increased sensitivity to UVA radiation in Escherichia coli JD Hoerter, AA Arnold, CS Ward, M Sauer, S Johnson, T Fleming, ... Journal of Photochemistry and Photobiology B: Biology 79 (2), 151-157, 2005 | 40 | 2005 |
Effect of UVA fluence rate on indicators of oxidative stress in human dermal fibroblasts JD Hoerter, CS Ward, KD Bale, AN Gizachew, R Graham, J Reynolds, ... International journal of biological sciences 4 (2), 63, 2008 | 34 | 2008 |
Progressive changes in a distributed neural circuit underlie breathing abnormalities in mice lacking MeCP2 TW Huang, MY Kochukov, CS Ward, J Merritt, K Thomas, T Nguyen, ... Journal of Neuroscience 36 (20), 5572-5586, 2016 | 33 | 2016 |
Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy N Spielmann, G Miller, TI Oprea, CW Hsu, G Fobo, G Frishman, ... Nature Cardiovascular Research 1 (2), 157-173, 2022 | 21 | 2022 |
Treatment of cardiac arrhythmias in a mouse model of Rett syndrome with Na+-channel-blocking antiepileptic drugs JA Herrera, CS Ward, MR Pitcher, AK Percy, S Skinner, WE Kaufmann, ... Disease models & mechanisms 8 (4), 363-371, 2015 | 21 | 2015 |
Genetic rodent models of brain disorders: Perspectives on experimental approaches and therapeutic strategies CM McGraw, CS Ward, RC Samaco American Journal of Medical Genetics Part C: Seminars in Medical Genetics …, 2017 | 19 | 2017 |