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Jinkuk Choi
Jinkuk Choi
Scientific Director at Biogen
Verified email at biogen.com
Title
Cited by
Cited by
Year
Telomerase modulates Wnt signalling by association with target gene chromatin
JI Park, AS Venteicher, JY Hong, J Choi, S Jun, M Shkreli, W Chang, ...
Nature 460 (7251), 66-72, 2009
8212009
Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice
A Sacco, F Mourkioti, R Tran, J Choi, M Llewellyn, P Kraft, M Shkreli, ...
Cell 143 (7), 1059-1071, 2010
5762010
TERT promotes epithelial proliferation through transcriptional control of a Myc-and Wnt-related developmental program
J Choi, LK Southworth, KY Sarin, AS Venteicher, W Ma, W Chang, ...
PLoS genetics 4 (1), e10, 2008
3922008
Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells
LFZ Batista, MF Pech, FL Zhong, HN Nguyen, KT Xie, AJ Zaug, SM Crary, ...
Nature 474 (7351), 399-402, 2011
2812011
IDOL stimulates clathrin-independent endocytosis and MVB-mediated lysosomal degradation of the LDLR
E Scotti, M Calamai, CN Goulbourne, L Zhang, C Hong, RR Lin, J Choi, ...
Molecular and cellular biology, 2013
932013
Telomere protection and TRF2 expression are enhanced by the canonical Wnt signalling pathway
I Diala, N Wagner, F Magdinier, M Shkreli, M Sirakov, S Bauwens, ...
EMBO reports 14 (4), 356-363, 2013
832013
Telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivo
S Rajaraman, J Choi, P Cheung, V Beaudry, H Moore, SE Artandi
Proceedings of the National Academy of Sciences 104 (45), 17747, 2007
592007
Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain
EJ Middleman, J Choi, AS Venteicher, P Cheung, SE Artandi
Molecular and cellular biology 26 (6), 2146-2159, 2006
382006
The E3 ubiquitin ligase Idol controls brain LDL receptor expression, ApoE clearance, and Aβ amyloidosis
J Choi, J Gao, J Kim, C Hong, J Kim, P Tontonoz
Science translational medicine 7 (314), 314ra184-314ra184, 2015
372015
The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning
J Gao, M Marosi, J Choi, JM Achiro, S Kim, S Li, K Otis, KC Martin, ...
Elife 6, e29178, 2017
282017
A novel type 2 diabetes mouse model of combined diabetic kidney disease and atherosclerosis
KE Bornfeldt, F Kramer, A Batorsky, J Choi, KL Hudkins, P Tontonoz, ...
The American journal of pathology 188 (2), 343-352, 2018
242018
Stem cell aging and aberrant differentiation within the niche
J Choi, S Artandi
Cell Stem Cell 5 (1), 6-8, 2009
162009
Metabolism: Drug discovery goes for a swim
J Choi, P Tontonoz
Nature Chemical Biology 9 (2), 68-69, 2013
6*2013
Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain
BE Cook, S Nag, R Arakawa, EYS Lin, N Stratman, K Guckian, H Hering, ...
Journal of Nuclear Medicine 64 (10), 1588-1593, 2023
22023
Glycoside hydrolases as therapeutic targets for CNS indications
J Choi, K Guckian, H Hering, NE Genung
Medicinal Chemistry Reviews 56, 343-365, 2021
2021
Proteomics studies to investigate alterations in the tau interactome under conditions of elevated cellular O‐GlcNAcylation: Molecular and cell biology/tau
J Choi, DM Walther, B Bajrami, A Halftermeyer, HB Rajamohamed Sait, ...
Alzheimer's & Dementia 16, e038276, 2020
2020
P4‐058: A NOVEL TRANSGENIC RAT MODEL THAT PRESENTS PATHOPHYSIOLOGICAL LEVELS OF HUMAN TAU IN CSF, AXONOPATHY, HIPPOCAMPAL NETWORK DISRUPTION, AND COGNITIVE DEFICITS
J Choi, J Czerkowicz, M Craft, M Stoiljkovic, P Leach, V Bieber, ...
Alzheimer's & Dementia 15, P1295-P1295, 2019
2019
A Novel Model of Type 2 Diabetes-accelerated Atherosclerosis and Microvascular Complications
KE Bornfeldt, F Kramer, A Batorsky, J Choi, KL Hudkins, CE Alpers, ...
DIABETES 65, A125-A125, 2016
2016
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