Telomerase modulates Wnt signalling by association with target gene chromatin JI Park, AS Venteicher, JY Hong, J Choi, S Jun, M Shkreli, W Chang, ... Nature 460 (7251), 66-72, 2009 | 821 | 2009 |
Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice A Sacco, F Mourkioti, R Tran, J Choi, M Llewellyn, P Kraft, M Shkreli, ... Cell 143 (7), 1059-1071, 2010 | 576 | 2010 |
TERT promotes epithelial proliferation through transcriptional control of a Myc-and Wnt-related developmental program J Choi, LK Southworth, KY Sarin, AS Venteicher, W Ma, W Chang, ... PLoS genetics 4 (1), e10, 2008 | 392 | 2008 |
Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells LFZ Batista, MF Pech, FL Zhong, HN Nguyen, KT Xie, AJ Zaug, SM Crary, ... Nature 474 (7351), 399-402, 2011 | 281 | 2011 |
IDOL stimulates clathrin-independent endocytosis and MVB-mediated lysosomal degradation of the LDLR E Scotti, M Calamai, CN Goulbourne, L Zhang, C Hong, RR Lin, J Choi, ... Molecular and cellular biology, 2013 | 93 | 2013 |
Telomere protection and TRF2 expression are enhanced by the canonical Wnt signalling pathway I Diala, N Wagner, F Magdinier, M Shkreli, M Sirakov, S Bauwens, ... EMBO reports 14 (4), 356-363, 2013 | 83 | 2013 |
Telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivo S Rajaraman, J Choi, P Cheung, V Beaudry, H Moore, SE Artandi Proceedings of the National Academy of Sciences 104 (45), 17747, 2007 | 59 | 2007 |
Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain EJ Middleman, J Choi, AS Venteicher, P Cheung, SE Artandi Molecular and cellular biology 26 (6), 2146-2159, 2006 | 38 | 2006 |
The E3 ubiquitin ligase Idol controls brain LDL receptor expression, ApoE clearance, and Aβ amyloidosis J Choi, J Gao, J Kim, C Hong, J Kim, P Tontonoz Science translational medicine 7 (314), 314ra184-314ra184, 2015 | 37 | 2015 |
The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning J Gao, M Marosi, J Choi, JM Achiro, S Kim, S Li, K Otis, KC Martin, ... Elife 6, e29178, 2017 | 28 | 2017 |
A novel type 2 diabetes mouse model of combined diabetic kidney disease and atherosclerosis KE Bornfeldt, F Kramer, A Batorsky, J Choi, KL Hudkins, P Tontonoz, ... The American journal of pathology 188 (2), 343-352, 2018 | 24 | 2018 |
Stem cell aging and aberrant differentiation within the niche J Choi, S Artandi Cell Stem Cell 5 (1), 6-8, 2009 | 16 | 2009 |
Metabolism: Drug discovery goes for a swim J Choi, P Tontonoz Nature Chemical Biology 9 (2), 68-69, 2013 | 6* | 2013 |
Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain BE Cook, S Nag, R Arakawa, EYS Lin, N Stratman, K Guckian, H Hering, ... Journal of Nuclear Medicine 64 (10), 1588-1593, 2023 | 2 | 2023 |
Glycoside hydrolases as therapeutic targets for CNS indications J Choi, K Guckian, H Hering, NE Genung Medicinal Chemistry Reviews 56, 343-365, 2021 | | 2021 |
Proteomics studies to investigate alterations in the tau interactome under conditions of elevated cellular O‐GlcNAcylation: Molecular and cell biology/tau J Choi, DM Walther, B Bajrami, A Halftermeyer, HB Rajamohamed Sait, ... Alzheimer's & Dementia 16, e038276, 2020 | | 2020 |
P4‐058: A NOVEL TRANSGENIC RAT MODEL THAT PRESENTS PATHOPHYSIOLOGICAL LEVELS OF HUMAN TAU IN CSF, AXONOPATHY, HIPPOCAMPAL NETWORK DISRUPTION, AND COGNITIVE DEFICITS J Choi, J Czerkowicz, M Craft, M Stoiljkovic, P Leach, V Bieber, ... Alzheimer's & Dementia 15, P1295-P1295, 2019 | | 2019 |
A Novel Model of Type 2 Diabetes-accelerated Atherosclerosis and Microvascular Complications KE Bornfeldt, F Kramer, A Batorsky, J Choi, KL Hudkins, CE Alpers, ... DIABETES 65, A125-A125, 2016 | | 2016 |