| Elevated Beclin 1 expression is correlated with HIF-1α in predicting poor prognosis of nasopharyngeal carcinoma XB Wan, XJ Fan, MY Chen, J Xiang, PY Huang, L Guo, XY Wu, J Xu, ... Autophagy 6 (3), 395-404, 2010 | 156 | 2010 |
| Purine metabolism regulates DNA repair and therapy resistance in glioblastoma W Zhou, Y Yao, AJ Scott, K Wilder-Romans, JJ Dresser, CK Werner, ... Nature communications 11 (1), 3811, 2020 | 129 | 2020 |
| Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute … J Rao, DR Xu, FM Zheng, ZJ Long, SS Huang, X Wu, WH Zhou, ... Journal of translational medicine 9, 1-15, 2011 | 114 | 2011 |
| Neddylation E2 UBE2F promotes the survival of lung cancer cells by activating CRL5 to degrade NOXA via the K11 linkage W Zhou, J Xu, H Li, M Xu, ZJ Chen, W Wei, Z Pan, Y Sun Clinical Cancer Research 23 (4), 1104-1116, 2017 | 108 | 2017 |
| Metabolic abnormalities in glioblastoma and metabolic strategies to overcome treatment resistance W Zhou, DR Wahl Cancers 11 (9), 1231, 2019 | 107 | 2019 |
| Development and validation of a radiopathomics model to predict pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a multicentre … L Feng, Z Liu, C Li, Z Li, X Lou, L Shao, Y Wang, Y Huang, H Chen, ... The Lancet Digital Health 4 (1), e8-e17, 2022 | 105 | 2022 |
| Low expression of Beclin 1, associated with high Bcl-xL, predicts a malignant phenotype and poor prognosis of gastric cancer WH Zhou, F Tang, J Xu, X Wu, SB Yang, ZY Feng, YG Ding, XB Wan, ... Autophagy 8 (3), 389-400, 2012 | 98 | 2012 |
| Aurora-A identifies early recurrence and poor prognosis and promises a potential therapeutic target in triple negative breast cancer J Xu, X Wu, W Zhou, A Liu, J Wu, J Deng, C Yue, S Yang, J Wang, Z Yuan, ... PloS one 8 (2), e56919, 2013 | 92 | 2013 |
| Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases W Zhou, W Wei, Y Sun Cell research 23 (5), 599-619, 2013 | 90 | 2013 |
| A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation H Zhou, J Lu, L Liu, D Bernard, CY Yang, E Fernandez-Salas, ... Nature communications 8 (1), 1150, 2017 | 83 | 2017 |
| UBE2M is a stress-inducible dual E2 for neddylation and ubiquitylation that promotes targeted degradation of UBE2F W Zhou, J Xu, M Tan, H Li, H Li, W Wei, Y Sun Molecular cell 70 (6), 1008-1024. e6, 2018 | 71 | 2018 |
| Aurora-A contributes to cisplatin resistance and lymphatic metastasis in non-small cell lung cancer and predicts poor prognosis J Xu, C Yue, W Zhou, Y Qian, Y Zhang, S Wang, A Liu, Q Liu Journal of translational medicine 12, 1-14, 2014 | 69 | 2014 |
| The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor J Xu, W Zhou, F Yang, G Chen, H Li, Y Zhao, P Liu, H Li, M Tan, X Xiong, ... Nature communications 8 (1), 14002, 2017 | 68 | 2017 |
| High-affinity peptidomimetic inhibitors of the DCN1-UBC12 protein–protein interaction H Zhou, W Zhou, B Zhou, L Liu, TR Chern, K Chinnaswamy, J Lu, ... Journal of Medicinal Chemistry 61 (5), 1934-1950, 2018 | 54 | 2018 |
| Autophagic protein Beclin 1 serves as an independent positive prognostic biomarker for non-small cell lung cancer W Zhou, C Yue, J Deng, R Hu, J Xu, L Feng, Q Lan, W Zhang, D Ji, J Wu, ... PLoS One 8 (11), e80338, 2013 | 42 | 2013 |
| A urora‐A activation, correlated with hypoxia‐inducible factor‐1α, promotes radiochemoresistance and predicts poor outcome for nasopharyngeal carcinoma XB Wan, XJ Fan, PY Huang, D Dong, Y Zhang, MY Chen, J Xiang, J Xu, ... Cancer science 103 (8), 1586-1594, 2012 | 37 | 2012 |
| SAG/RBX2 E3 ligase complexes with UBCH10 and UBE2S E2s to ubiquitylate β-TrCP1 via K11-linkage for degradation P Kuang, M Tan, W Zhou, Q Zhang, Y Sun Scientific Reports 6 (1), 37441, 2016 | 35 | 2016 |
| Up-regulation of P21 inhibits TRAIL-mediated extrinsic apoptosis, contributing resistance to SAHA in acute myeloid leukemia cells X Wu, N Yang, W Zhou, J Xu, J Chen, F Zheng, Z Long, C Yue, K Ai, L Liu, ... Cellular Physiology and Biochemistry 34 (2), 506-518, 2014 | 34 | 2014 |
| Inhibition of Bcl-xL overcomes polyploidy resistance and leads to apoptotic cell death in acute myeloid leukemia cells W Zhou, J Xu, E Gelston, X Wu, Z Zou, B Wang, Y Zeng, H Wang, A Liu, ... Oncotarget 6 (25), 21557, 2015 | 33 | 2015 |
| SAG/RBX2 is a novel substrate of NEDD4-1 E3 ubiquitin ligase and mediates NEDD4-1 induced chemosensitization W Zhou, J Xu, Y Zhao, Y Sun Oncotarget 5 (16), 6746, 2014 | 33 | 2014 |
