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Patrick Barth
Patrick Barth
Associate Professor of Bioengineering, Swiss Federal School of Technology, Lausanne
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Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
5632020
Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment
I Kufareva, M Rueda, V Katritch, RC Stevens, R Abagyan
Structure 19 (8), 1108-1126, 2011
3452011
Closing in on the resting state of the Shaker K+ channel
MM Pathak, V Yarov-Yarovoy, G Agarwal, B Roux, P Barth, S Kohout, ...
Neuron 56 (1), 124-140, 2007
3242007
Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008
M Michino, E Abola, GPCR Dock 2008 Participants, CL Brooks III, ...
Nature Reviews Drug Discovery 8 (6), 455-463, 2009
3042009
Toward high-resolution prediction and design of transmembrane helical protein structures
P Barth, J Schonbrun, D Baker
Proceedings of the National Academy of Sciences 104 (40), 15682-15687, 2007
2662007
Toward high-resolution prediction and design of transmembrane helical protein structures
P Barth, J Schonbrun, D Baker
Proceedings of the National Academy of Sciences 104 (40), 15682-15687, 2007
2662007
Protein–Protein Interactions Governing Septin Heteropentamer Assembly and Septin Filament Organization in Saccharomyces cerevisiae
M Versele, B Gullbrand, MJ Shulewitz, VJ Cid, S Bahmanyar, RE Chen, ...
Molecular biology of the cell 15 (10), 4568-4583, 2004
1992004
Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges
I Kufareva, V Katritch, RC Stevens, R Abagyan
Structure 22 (8), 1120-1139, 2014
1812014
Prediction of membrane protein structures with complex topologies using limited constraints
P Barth, B Wallner, D Baker
Proceedings of the National Academy of Sciences 106 (5), 1409-1414, 2009
1792009
Structure of a D2 dopamine receptor–G-protein complex in a lipid membrane
J Yin, KYM Chen, MJ Clark, M Hijazi, P Kumari, X Bai, RK Sunahara, ...
Nature 584 (7819), 125-129, 2020
1642020
The structure of a receptor with two associating transmembrane domains on the cell surface: integrin αIIbβ3
J Zhu, BH Luo, P Barth, J Schonbrun, D Baker, TA Springer
Molecular cell 34 (2), 234-249, 2009
1642009
Platon: identification and characterization of bacterial plasmid contigs in short-read draft assemblies exploiting protein sequence-based replicon distribution scores
O Schwengers, P Barth, L Falgenhauer, T Hain, T Chakraborty, ...
Microbial genomics 6 (10), e000398, 2020
1232020
Ferredoxin reduction by photosystem I from Synechocystis sp. PCC 6803: toward an understanding of the respective roles of subunits PsaD and PsaE in ferredoxin binding
P Barth, B Lagoutte, P Sétif
Biochemistry 37 (46), 16233-16241, 1998
791998
An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function
L Wang, K Pang, K Han, CJ Adamski, W Wang, L He, JK Lai, VV Bondar, ...
Molecular psychiatry 25 (10), 2534-2555, 2020
702020
Survivin-specific T cell receptor targets tumor but not T cells
C Arber, X Feng, H Abhyankar, E Romero, MF Wu, HE Heslop, P Barth, ...
The Journal of clinical investigation 125 (1), 157-168, 2015
672015
Computational design of G Protein-Coupled Receptor allosteric signal transductions
KYM Chen, D Keri, P Barth
Nature Chemical Biology 16 (1), 77-86, 2020
572020
Accurate, conformation-dependent predictions of solvent effects on protein ionization constants
P Barth, T Alber, PB Harbury
Proceedings of the National Academy of Sciences 104 (12), 4898-4903, 2007
542007
Naturally evolved G protein-coupled receptors adopt metastable conformations
KYM Chen, F Zhou, BG Fryszczyn, P Barth
Proceedings of the National Academy of Sciences 109 (33), 13284-13289, 2012
522012
Essential role of a single arginine of photosystem I in stabilizing the electron transfer complex with ferredoxin
P Barth, I Guillouard, P Sétif, B Lagoutte
Journal of biological chemistry 275 (10), 7030-7036, 2000
512000
Evolutionary-guided de novo structure prediction of self-associated transmembrane helical proteins with near-atomic accuracy
Y Wang, P Barth
Nature Communications 6 (1), 7196, 2015
402015
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