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Sara Deschaine
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A deeper insight into how GABA-B receptor agonism via baclofen may affect alcohol seeking and consumption: lessons learned from a human laboratory investigation
M Farokhnia, SL Deschaine, A Sadighi, LA Farinelli, MR Lee, F Akhlaghi, ...
Molecular psychiatry 26 (2), 545-555, 2021
302021
Influence of route of administration and lipidation of apolipoprotein AI peptide on pharmacokinetics and cholesterol mobilization
J Tang, D Li, L Drake, W Yuan, S Deschaine, EE Morin, R Ackermann, ...
Journal of lipid research 58 (1), 124-136, 2017
292017
From “hunger hormone” to “it’s complicated”: ghrelin beyond feeding control
SL Deschaine, L Leggio
Physiology 37 (1), 5-15, 2022
272022
Parsing out the role of dopamine D4 receptor gene (DRD4) on alcohol‐related phenotypes: A meta‐analysis and systematic review
AM Daurio, SL Deschaine, A Modabbernia, L Leggio
Addiction biology 25 (3), e12770, 2020
222020
A closer look at alcohol‐induced changes in the ghrelin system: novel insights from preclinical and clinical data
SL Deschaine, M Farokhnia, A Gregory‐Flores, LJ Zallar, ZB You, H Sun, ...
Addiction biology 27 (1), e13033, 2022
202022
Effects of exogenous ghrelin administration and ghrelin receptor blockade, in combination with alcohol, on peripheral inflammatory markers in heavy-drinking individuals …
M Farokhnia, J Portelli, MR Lee, GR McDiarmid, V Munjal, KM Abshire, ...
Brain research 1740, 146851, 2020
142020
Neuroendocrine response to exogenous ghrelin administration, combined with alcohol, in heavy-drinking individuals: findings from a randomized, double-blind, placebo-controlled …
M Farokhnia, KM Abshire, A Hammer, SL Deschaine, A Saravanakumar, ...
International Journal of Neuropsychopharmacology 24 (6), 464-476, 2021
102021
Understanding plasma treatment effect on human acyl-ghrelin concentrations.
SL Deschaine, L Leggio
European Review for Medical & Pharmacological Sciences 24 (3), 2020
102020
Role of the ghrelin system in alcohol use disorder and alcohol‐associated liver disease: A narrative review
KK Kharbanda, M Farokhnia, SL Deschaine, R Bhargava, ...
Alcoholism: Clinical and Experimental Research 46 (12), 2149-2159, 2022
72022
Investigating the link between serum concentrations of brain-derived neurotrophic factor and behavioral measures in anxious alcohol-dependent individuals
J Portelli, M Farokhnia, SL Deschaine, JT Battista, MR Lee, X Li, D Ron, ...
Alcohol 89, 75-83, 2020
62020
Peripheral proinflammatory markers are upregulated in abstinent alcohol-dependent patients but are not affected by cognitive bias modification: preliminary findings
J Portelli, CE Wiers, X Li, SL Deschaine, GR McDiarmid, F Bermpohl, ...
Drug and alcohol dependence 204, 107553, 2019
62019
Initial pharmacological characterization of a major hydroxy metabolite of PF-5190457: inverse agonist activity of PF-6870961 at the ghrelin receptor
SL Deschaine, MA Hedegaard, CL Pince, M Farokhnia, JE Moose, ...
Journal of Pharmacology and Experimental Therapeutics 386 (2), 117-128, 2023
52023
Effect of intravenous ghrelin administration, combined with alcohol, on circulating metabolome in heavy drinking individuals with alcohol use disorder
O Kärkkäinen, M Farokhnia, A Klåvus, S Auriola, M Lehtonen, ...
Alcoholism: Clinical and Experimental Research 45 (11), 2207-2216, 2021
52021
A role for the CD38 rs3796863 polymorphism in alcohol and monetary reward: evidence from CD38 knockout mice and alcohol self-administration, [11C]-raclopride …
MR Lee, JH Shin, S Deschaine, AM Daurio, BL Stangl, J Yan, ...
The American Journal of Drug and Alcohol Abuse 46 (2), 167-179, 2020
42020
Leptin gene and Leptin receptor gene polymorphisms in alcohol use disorder: findings related to psychopathology
BD Browning, ML Schwandt, M Farokhnia, SL Deschaine, ...
Frontiers in Psychiatry 12, 723059, 2021
32021
Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet
L Leggio, A Leko, A Gregory-Flores, R Marchette, J Gomez, ...
Research Square, 2023
2023
A Human Laboratory Study on the Effects of a Novel Ghrelin Receptor Inverse Agonist Competitive Antagonist on Alcohol and Food-Related Behaviors in Individuals With Alcohol Use …
M Faulkner, M Farokhnia, L Farinelli, S Deschaine, B Browning, ...
NEUROPSYCHOPHARMACOLOGY 47 (SUPPL 1), 311-312, 2022
2022
PHARMACOLOGICAL CHARACTERIZATION OF A GHRELIN RECEPTOR ANTAGONIST/INVERSE AGONIST, PF-5190457, AND ITS MAJOR ACTIVE HYDROXY METABOLITE
SL Deschaine, MA Hedegaard, A Sulima, J Moose, IA Stock, JL Hougland, ...
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 45, 146A-146A, 2021
2021
EXAMININGALCOHOL-INDUCED CHANGES IN THE GHRELIN SYSTEM-FINDINGS FROM PRECLINICAL AND HUMAN EXPERIMENTS
SL Deschaine, M Farokhnia, L Leggio
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 45, 51A-52A, 2021
2021
Alcohol Acutely Suppresses Ghrelin Through an Indirect Mechanism-Converging Evidence From Preclinical and Clinical Data
S Deschaine, M Farokhnia, A Gregory-Flores, L Zallar, ZB You, H Sun, ...
NEUROPSYCHOPHARMACOLOGY 45 (SUPPL 1), 265-266, 2020
2020
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