| Balancing repair and tolerance of DNA damage caused by alkylating agents D Fu, JA Calvo, LD Samson Nature Reviews Cancer 12 (2), 104-120, 2012 | 1053 | 2012 |
| Dual functions of largest NURF subunit NURF301 in nucleosome sliding and transcription factor interactions H Xiao, R Sandaltzopoulos, HM Wang, A Hamiche, R Ranallo, KM Lee, ... Molecular cell 8 (3), 531-543, 2001 | 309 | 2001 |
| Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation D Fu, K Collins Molecular cell 28 (5), 773-785, 2007 | 285 | 2007 |
| Distinct biogenesis pathways for human telomerase RNA and H/ACA small nucleolar RNAs D Fu, K Collins Molecular cell 11 (5), 1361-1372, 2003 | 268 | 2003 |
| Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival D Fu, JAN Brophy, CTY Chan, KA Atmore, U Begley, RS Paules, ... Molecular and cellular biology 30 (10), 2449-2459, 2010 | 220 | 2010 |
| Acidic pH is a metabolic switch for 2-hydroxyglutarate generation and signaling SM Nadtochiy, X Schafer, D Fu, K Nehrke, J Munger, PS Brookes Journal of Biological Chemistry 291 (38), 20188-20197, 2016 | 133 | 2016 |
| Human telomerase and Cajal body ribonucleoproteins share a unique specificity of Sm protein association D Fu, K Collins Genes & development 20 (5), 531-536, 2006 | 107 | 2006 |
| TRMT1-catalyzed tRNA modifications are required for redox homeostasis to ensure proper cellular proliferation and oxidative stress survival JM Dewe, BL Fuller, JM Lentini, SM Kellner, D Fu Molecular and cellular biology 37 (21), e00214-17, 2017 | 106 | 2017 |
| Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis D Fu, JJ Jordan, LD Samson Genes & development 27 (10), 1089-1100, 2013 | 91 | 2013 |
| Direct repair of 3, N4-ethenocytosine by the human ALKBH2 dioxygenase is blocked by the AAG/MPG glycosylase D Fu, LD Samson DNA repair 11 (1), 46-52, 2012 | 52 | 2012 |
| The emerging impact of tRNA modifications in the brain and nervous system J Ramos, D Fu Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1862 (3), 412-428, 2019 | 51 | 2019 |
| DALRD3 encodes a protein mutated in epileptic encephalopathy that targets arginine tRNAs for 3-methylcytosine modification JM Lentini, HS Alsaif, E Faqeih, FS Alkuraya, D Fu Nature communications 11 (1), 2510, 2020 | 41 | 2020 |
| Disease-associated human telomerase RNA variants show loss of function for telomere synthesis without dominant-negative interference TM Errington, D Fu, JMY Wong, K Collins Molecular and cellular biology, 2008 | 37 | 2008 |
| Isolation of Pichia pastoris genes involved in ER‐to‐Golgi transport WE Payne, CA Kaiser, BJ Bevis, J Soderholm, D Fu, IB Sears, BS Glick Yeast 16 (11), 979-993, 2000 | 36 | 2000 |
| The interaction between ALKBH2 DNA repair enzyme and PCNA is direct, mediated by the hydrophobic pocket of PCNA and perturbed in naturally-occurring ALKBH2 variants D Fu, LD Samson, U Hübscher, B van Loon DNA repair 35, 13-18, 2015 | 33 | 2015 |
| Broadly applicable oligonucleotide mass spectrometry for the analysis of RNA writers and erasers in vitro F Hagelskamp, K Borland, J Ramos, AG Hendrick, D Fu, S Kellner Nucleic acids research 48 (7), e41-e41, 2020 | 31 | 2020 |
| An intellectual disability‐associated missense variant in TRMT1 impairs tRNA modification and reconstitution of enzymatic activity K Zhang, JM Lentini, CT Prevost, MO Hashem, FS Alkuraya, D Fu Human mutation 41 (3), 600-607, 2020 | 31 | 2020 |
| Biallelic variants in CTU2 cause DREAM‐PL syndrome and impair thiolation of tRNA wobble U34 R Shaheen, P Mark, CT Prevost, A AlKindi, A Alhag, F Estwani, ... Human mutation 40 (11), 2108-2120, 2019 | 29 | 2019 |
| Formation of tRNA wobble inosine in humans is disrupted by a millennia-old mutation causing intellectual disability J Ramos, L Han, Y Li, F Hagelskamp, SM Kellner, FS Alkuraya, ... Molecular and cellular biology, 2019 | 28 | 2019 |
| THUMPD1 bi-allelic variants cause loss of tRNA acetylation and a syndromic neurodevelopmental disorder M Broly, BV Polevoda, KM Awayda, N Tong, J Lentini, T Besnard, W Deb, ... The American Journal of Human Genetics 109 (4), 587-600, 2022 | 22 | 2022 |
Leona D. SamsonProfessor Emerita, Biological Engineering, Biology MITVerified email at mit.edu
