| Membrane transporters in drug development KM Giacomini, SM Huang, DJ Tweedie, LZ Benet, KLR Brouwer, X Chu, ... Nature Reviews Drug Discovery 9 (3), 215-236, 2010 | 3484* | 2010 |
| The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. I Leier, G Jedlitschky, U Buchholz, SPC Cole, RG Deeley, D Keppler Journal of Biological Chemistry 269 (45), 27807-27810, 1994 | 1082 | 1994 |
| Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance J König, AT Nies, Y Cui, I Leier, D Keppler Biochimica et Biophysica Acta (BBA)-Biomembranes 1461 (2), 377-394, 1999 | 990 | 1999 |
| Glycogen determination with amyloglucosidase D Keppler, K Decker Methods of Enzymatic Analysis (Bergmeyer, HU, editor) 4, 1127-1131, 1974 | 948* | 1974 |
| Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells Y Cui, J König, U Buchholz, H Spring, I Leier, D Keppler Molecular Pharmacology 55 (5), 929-937, 1999 | 881 | 1999 |
| cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats M Büchler, J König, M Brom, J Kartenbeck, H Spring, T Horie, D Keppler Journal of Biological Chemistry 271 (25), 15091-15098, 1996 | 804 | 1996 |
| Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump G Jedlitschky, I Leier, U Buchholz, K Barnouin, G Kurz, D Keppler Cancer Research 56 (5), 988-994, 1996 | 768 | 1996 |
| A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane J König, Y Cui, AT Nies, D Keppler American Journal of Physiology-Gastrointestinal and Liver Physiology 278 (1 …, 2000 | 764 | 2000 |
| Experimental hepatitis induced by D-galactosamine D Keppler, R Lesch, W Reutter, K Decker Experimental and Molecular Pathology 9 (2), 279-290, 1968 | 751 | 1968 |
| Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide J König, Y Cui, AT Nies, D Keppler Journal of Biological Chemistry 275 (30), 23161-23168, 2000 | 641 | 2000 |
| Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6 Y Cui, J König, I Leier, U Buchholz, D Keppler Journal of Biological Chemistry 276 (13), 9626-9630, 2001 | 628 | 2001 |
| Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane J König, D Rost, Y Cui, D Keppler Hepatology 29 (4), 1156-1163, 1999 | 609 | 1999 |
| The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis M Trauner, M Arrese, CJ Soroka, M Ananthanarayanan, TA Koeppel, ... Gastroenterology 113 (1), 255-264, 1997 | 587 | 1997 |
| The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides G Jedlitschky, B Burchell, D Keppler Journal of Biological Chemistry 275 (39), 30069-30074, 2000 | 572 | 2000 |
| Galactosamine hepatitis: key role of the nucleotide deficiency period in the pathogenesis of cell injury and cell death K Decker, D Keppler Reviews of Physiology, Biochemistry and Pharmacology, Volume 71, 77-106, 1974 | 570* | 1974 |
| ATP-dependent Transport of Glutathione S-Conjugates by the Multidrug Resistance-associated Protein G Jedlitschky, I Leier, U Buchholz, M Center, D Keppler Cancer Research 54 (18), 4833-4836, 1994 | 556 | 1994 |
| Absence of the canalicular isoform of the MRP gene–encoded conjugate export pump from the hepatocytes in Dubin‐Johnson syndrome J Kartenbeck, U Leuschner, R Mayer, D Keppler Hepatology 23 (5), 1061-1066, 1996 | 513 | 1996 |
| The apical conjugate efflux pump ABCC2 (MRP2) AT Nies, D Keppler Pflügers Archiv-European Journal of Physiology 453, 643-659, 2007 | 472 | 2007 |
| Expression and immunolocalization of the multidrug resistance proteins, MRP1–MRP6 (ABCC1–ABCC6), in human brain AT Nies, G Jedlitschky, J König, C Herold-Mende, HH Steiner, HP Schmitt, ... Neuroscience 129 (2), 349-360, 2004 | 472 | 2004 |
| Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane M Rius, AT Nies, J Hummel‐Eisenbeiss, G Jedlitschky, D Keppler Hepatology 38 (2), 374-384, 2003 | 444 | 2003 |
Jörg KönigFriedrich-Alexander-Universität Erlangen, Prof. Dr.Verified email at fau.de
