| Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. I Grundke-Iqbal, K Iqbal, YC Tung, M Quinlan, HM Wisniewski, LI Binder Proceedings of the National Academy of Sciences 83 (13), 4913-4917, 1986 | 4662 | 1986 |
| Microtubule-associated protein tau. A component of Alzheimer paired helical filaments. I Grundke-Iqbal, K Iqbal, M Quinlan, YC Tung, MS Zaidi, HM Wisniewski Journal of Biological Chemistry 261 (13), 6084-6089, 1986 | 2346 | 1986 |
| Defeating Alzheimer's disease and other dementias: a priority for European science and society B Winblad, P Amouyel, S Andrieu, C Ballard, C Brayne, H Brodaty, ... The Lancet Neurology 15 (5), 455-532, 2016 | 1824 | 2016 |
| Tau pathology in Alzheimer disease and other tauopathies K Iqbal, AC Alonso, S Chen, MO Chohan, E El-Akkad, CX Gong, ... Biochimica et Biophysica Acta (BBA)-molecular basis of Disease 1739 (2-3 …, 2005 | 1408 | 2005 |
| Tau in Alzheimer disease and related tauopathies K Iqbal, F Liu, CX Gong, I Grundke-Iqbal Current Alzheimer Research 7 (8), 656-664, 2010 | 1251 | 2010 |
| Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments AC Alonso, T Zaidi, M Novak, I Grundke-Iqbal, K Iqbal Proceedings of the National Academy of Sciences 98 (12), 6923-6928, 2001 | 1189 | 2001 |
| Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules AC Alonso, I Grundke-Iqbal, K Iqbal Nature medicine 2 (7), 783-787, 1996 | 1062 | 1996 |
| Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease. E Köpke, YC Tung, S Shaikh, AC Alonso, K Iqbal, I Grundke-Iqbal Journal of Biological Chemistry 268 (32), 24374-24384, 1993 | 1051 | 1993 |
| Accumulation of abnormally phosphorylated τ precedes the formation of neurofibrillary tangles in Alzheimer's disease C Bancher, C Brunner, H Lassmann, H Budka, K Jellinger, G Wiche, ... Brain research 477 (1-2), 90-99, 1989 | 1013 | 1989 |
| Improved discrimination of AD patients using β-amyloid(1-42) and tau levels in CSF F Hulstaert, K Blennow, A Ivanoiu, HC Schoonderwaldt, ... Neurology 52 (8), 1555-1555, 1999 | 950 | 1999 |
| Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease. AC Alonso, T Zaidi, I Grundke-Iqbal, K Iqbal Proceedings of the National Academy of Sciences 91 (12), 5562-5566, 1994 | 939 | 1994 |
| Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation F Liu, I Grundke‐Iqbal, K Iqbal, CX Gong European Journal of Neuroscience 22 (8), 1942-1950, 2005 | 922 | 2005 |
| O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease F Liu, K Iqbal, I Grundke-Iqbal, GW Hart, CX Gong Proceedings of the National Academy of Sciences 101 (29), 10804-10809, 2004 | 916 | 2004 |
| Tau and neurodegenerative disease: the story so far K Iqbal, F Liu, CX Gong Nature reviews neurology 12 (1), 15-27, 2016 | 806 | 2016 |
| Mechanisms of tau-induced neurodegeneration K Iqbal, F Liu, CX Gong, AC Alonso, I Grundke-Iqbal Acta neuropathologica 118, 53-69, 2009 | 804 | 2009 |
| The lipophilic bullet hits the targets: medicinal chemistry of adamantane derivatives L Wanka, K Iqbal, PR Schreiner Chemical reviews 113 (5), 3516-3604, 2013 | 747 | 2013 |
| Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease CX Gong, K Iqbal Current medicinal chemistry 15 (23), 2321-2328, 2008 | 715 | 2008 |
| Post-translational modifications of tau protein in Alzheimer’s disease CX Gong, F Liu, I Grundke-Iqbal, K Iqbal Journal of neural transmission 112, 813-838, 2005 | 676 | 2005 |
| Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration JZ Wang, I Grundke‐Iqbal, K Iqbal European Journal of Neuroscience 25 (1), 59-68, 2007 | 671 | 2007 |
| Phosphoprotein phosphatase activities in Alzheimer disease brain CX Gong, TJ Singh, I Grundke‐Iqbal, K Iqbal Journal of neurochemistry 61 (3), 921-927, 1993 | 668 | 1993 |
