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Cytochromes P450 CYP94C1 and CYP94B3 catalyze two successive oxidation steps of plant hormone jasmonoyl-isoleucine for catabolic turnover T Heitz, E Widemann, R Lugan, L Miesch, P Ullmann, L Désaubry, ... Journal of Biological Chemistry 287 (9), 6296-6306, 2012 | 265 | 2012 |
PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis C Yan, L Gong, L Chen, M Xu, H Abou-Hamdan, M Tang, L Désaubry, ... Autophagy 16 (3), 419-434, 2020 | 243 | 2020 |
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Translational control of tumor immune escape via the eIF4F–STAT1–PD-L1 axis in melanoma M Cerezo, R Guemiri, S Druillennec, I Girault, H Malka-Mahieu, S Shen, ... Nature medicine 24 (12), 1877-1886, 2018 | 205 | 2018 |
Updates in anthracycline-mediated cardiotoxicity CG Nebigil, L Désaubry Frontiers in Pharmacology 9, 415242, 2018 | 181 | 2018 |
The natural anticancer compounds rocaglamides inhibit the Raf-MEK-ERK pathway by targeting prohibitin 1 and 2 G Polier, J Neumann, F Thuaud, N Ribeiro, C Gelhaus, H Schmidt, ... Chemistry & biology 19 (9), 1093-1104, 2012 | 171 | 2012 |
Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1 G Polier, J Ding, BV Konkimalla, D Eick, N Ribeiro, R Köhler, M Giaisi, ... Cell death & disease 2 (7), e182-e182, 2011 | 166 | 2011 |
Cancer wars: natural products strike back C Basmadjian, Q Zhao, E Bentouhami, A Djehal, CG Nebigil, RA Johnson, ... Frontiers in chemistry 2, 20, 2014 | 156 | 2014 |
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Recent Advances in the Synthesis of C2‐Functionalized Pyridines and Quinolines Using N‐Oxide Chemistry D Wang, L Désaubry, G Li, M Huang, S Zheng Advanced Synthesis & Catalysis 363 (1), 2-39, 2021 | 108 | 2021 |
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Molecular pathways: the eIF4F translation initiation complex—new opportunities for cancer treatment H Malka-Mahieu, M Newman, L Désaubry, C Robert, S Vagner Clinical Cancer Research 23 (1), 21-25, 2017 | 97 | 2017 |
Progress in copper complexes as anticancer agents R Tabti, N Tounsi, C Gaiddon, E Bentouhami, L Désaubry Med. Chem 7, 875-879, 2017 | 92 | 2017 |
Flavaglines: potent anticancer drugs that target prohibitins and the helicase eIF4A C Basmadjian, F Thuaud, N Ribeiro, L Désaubry Future medicinal chemistry 5 (18), 2185-2197, 2013 | 79 | 2013 |
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