Neuroinflammatory astrocyte subtypes in the mouse brain P Hasel, IVL Rose, JS Sadick, RD Kim, SA Liddelow Nature neuroscience 24 (10), 1475-1487, 2021 | 329 | 2021 |
CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes L Barbar, T Jain, M Zimmer, I Kruglikov, JS Sadick, M Wang, K Kalpana, ... Neuron 107 (3), 436-453.e12, 2020 | 142 | 2020 |
Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia K Hartmann, D Sepulveda-Falla, IVL Rose, C Madore, C Muth, ... Acta Neuropathologica Communications 7 (1), 1-15, 2019 | 106 | 2019 |
A reference human induced pluripotent stem cell line for large-scale collaborative studies CB Pantazis, A Yang, E Lara, JA McDonough, C Blauwendraat, L Peng, ... Cell Stem Cell 29 (12), 1685-1702. e22, 2022 | 76 | 2022 |
Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation S Kano, EY Choi, E Dohi, S Agarwal, DJ Chang, AM Wilson, BD Lo, ... Science signaling 12 (569), eaar2124, 2019 | 58 | 2019 |
CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states K Leng, IVL Rose, H Kim, W Xia, W Romero-Fernandez, B Rooney, ... Nature Neuroscience, 1-15, 2022 | 57 | 2022 |
Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis K Kleffman, G Levinson, IVL Rose, LM Blumenberg, SAA Shadaloey, ... Cancer Discovery, 2022 | 45 | 2022 |
Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin H Kim, K Leng, J Park, AG Sorets, S Kim, A Shostak, RJ Embalabala, ... Nature communications 13 (1), 6581, 2022 | 43 | 2022 |
Behavioral changes in mice lacking interleukin-33 E Dohi, EY Choi, IVL Rose, AS Murata, S Chow, M Niwa, S Kano eNeuro 4 (6), 2017 | 27 | 2017 |
Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time P Prakash, KP Jethava, N Korte, P Izquierdo, E Favuzzi, IVL Rose, ... Chemical Science 12 (32), 10901-10918, 2021 | 23 | 2021 |
Extracellular vesicles for research on psychiatric disorders S Kano, E Dohi, IVL Rose Schizophrenia bulletin 45 (1), 7-16, 2019 | 16 | 2019 |
Alterations in circulating extracellular vesicles underlie social stress-induced behaviors in mice S Sakamoto, D Mallah, DJ Medeiros, E Dohi, T Imai, IVL Rose, K Matoba, ... FEBS Open Bio, 2021 | 13 | 2021 |
mTOR controls neurotoxic lysosome exocytosis in inflammatory reactive astrocytes B Rooney, K Leng, F McCarthy, IVL Rose, KA Herrington, S Bax, MY Chin, ... bioRxiv, 2021.09. 11.459904, 2021 | 10 | 2021 |
Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically‐induced and immune‐mediated mouse models of multiple sclerosis HE Titus, H Xu, AP Robinson, PA Patel, Y Chen, D Fantini, V Eaton, ... Glia 70 (10), 1950-1970, 2022 | 6 | 2022 |
CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions E Li, C Benitez, SC Boggess, M Koontz, IVL Rose, N Draeger, OM Teter, ... bioRxiv, 2023 | 3 | 2023 |
Scalable, cell type-selective, AAV-based in vivo CRISPR screening in the mouse brain B Ramani, IVL Rose, A Pan, R Tian, K Ma, JJ Palop, M Kampmann bioRxiv, 2023 | 1 | 2023 |