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Luis A. Moran
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Thrombo-inflammation in cardiovascular disease: an expert consensus document from the Third Maastricht Consensus Conference on Thrombosis
E d’Alessandro, C Becker, W Bergmeier, C Bode, JH Bourne, H Brown, ...
Thrombosis and haemostasis 120 (04), 538-564, 2020
762020
A comprehensive tyrosine phosphoproteomic analysis reveals novel components of the platelet CLEC-2 signaling cascade
I Izquierdo, MN Barrachina, L Hermida-Nogueira, V Casas, LA Morán, ...
Thrombosis and Haemostasis 120 (02), 262-276, 2020
272020
The structure of CLEC-2: mechanisms of dimerization and higher-order clustering
EM Martin, M Zuidscherwoude, L Morán, Y Di, A García, SP Watson
Platelets 32 (6), 733-743, 2021
262021
Phosphoproteomic analysis of platelets in severe obesity uncovers platelet reactivity and signaling pathways alterations
MN Barrachina, L Hermida-Nogueira, LA Moran, V Casas, SM Hicks, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 41 (1), 478-490, 2021
202021
Deciphering the secretome of leukocyte-platelet rich fibrin: Towards a better understanding of its wound healing properties
L Hermida-Nogueira, MN Barrachina, LA Morán, S Bravo, P Diz, Á García, ...
Scientific Reports 10 (1), 14571, 2020
172020
Overcoming challenges in developing small molecule inhibitors for GPVI and CLEC-2
FN Damaskinaki, LA Moran, A Garcia, B Kellam, SP Watson
Platelets 32 (6), 744-752, 2021
162021
Galectin‐9 activates platelet ITAM receptors glycoprotein VI and C‐type lectin‐like receptor‐2
Z Zhi, NJ Jooss, Y Sun, M Colicchia, A Slater, LA Moran, HYF Cheung, ...
Journal of Thrombosis and Haemostasis 20 (4), 936-950, 2022
142022
Analysis of platelets from a diet-induced obesity rat model: elucidating platelet dysfunction in obesity
MN Barrachina, LA Morán, I Izquierdo, FF Casanueva, M Pardo, Á García
Scientific reports 10 (1), 13104, 2020
122020
La epigalocatequina-3-galato induce apoptosis en plaquetas
K Rosal, A Useche, L Morán, M López, G Bruges
Investigación Clínica 59 (2), 146-154, 2018
122018
Experimental validation of computerised models of clustering of platelet glycoprotein receptors that signal via tandem SH2 domain proteins
Z Maqsood, JC Clark, EM Martin, YFH Cheung, LA Morán, SET Watson, ...
PLOS Computational Biology 18 (11), e1010708, 2022
82022
Divalent nanobodies to platelet CLEC-2 can serve as agonists or antagonists
JC Clark, EM Martin, LA Morán, Y Di, X Wang, M Zuidscherwoude, ...
Communications Biology 6 (1), 376, 2023
52023
Katacine is a new ligand of CLEC-2 that acts as a platelet agonist
LA Morán, Y Di, MA Sowa, L Hermida-Nogueira, MN Barrachina, E Martin, ...
Thrombosis and haemostasis 122 (08), 1361-1368, 2022
52022
The pi3kδ inhibitor idelalisib diminishes platelet function and shows antithrombotic potential
MN Barrachina, I Izquierdo, L Hermida-Nogueira, LA Morán, A Pérez, ...
International Journal of Molecular Sciences 22 (7), 3304, 2021
42021
PF4 activates the c-Mpl–Jak2 pathway in platelets
RJ Buka, SJ Montague, LA Moran, EM Martin, A Slater, SP Watson, ...
Blood 143 (1), 64-69, 2024
32024
Trivalent nanobody-based ligands mediate powerful activation of GPVI, CLEC-2, and PEAR1 in human platelets whereas FcγRIIA requires a tetravalent ligand
EM Martin, JC Clark, SJ Montague, LA Morán, Y Di, LJ Bull, L Whittle, ...
Journal of Thrombosis and Haemostasis 22 (1), 271-285, 2024
32024
Inhibition of Src but not Syk causes weak reversal of GPVI-mediated platelet aggregation measured by light transmission aggregometry
HYF Cheung, LA Moran, A Sickmann, JWM Heemskerk, Á Garcia, ...
Platelets 33 (8), 1293-1300, 2022
22022
PB0397 Differential Requirement for Ligand Valency in the Activation of CLEC-2 in Human and Humanised Mouse Platelets
J Clark, E Martin, L Moran, Y Di, H Brown, B Nieswandt, D Stegner, ...
Research and Practice in Thrombosis and Haemostasis 7, 101664, 2023
2023
Inhibition of Src but not Syk causes weak reversal of GPVI-mediated platelet aggregation measured by light transmission aggregometry
C HYF, LA Moran, A Sickmann, JWM Heemskerk, Á Garcia, SP Watson
Deciphering glycoprotein VI signalling in platelet activation: integration …, 2023
2023
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