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Degang Liu
Degang Liu
Sartorius
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Title
Cited by
Cited by
Year
Discovery and characterization of small molecules that target the GTPase Ral
Nature 515 (7527), 443-447, 2014
1542014
Atractylenolide I enhances responsiveness to immune checkpoint blockade therapy by activating tumor antigen presentation
H Xu, K Van der Jeught, Z Zhou, L Zhang, T Yu, Y Sun, Y Li, C Wan, ...
The Journal of clinical investigation 131 (10), 2021
1032021
Probing the reaction mechanism of spore photoproduct lyase (SPL) via diastereoselectively labeled dinucleotide SP TpT substrates
L Yang, G Lin, D Liu, KJ Dria, J Telser, L Li
Journal of the American Chemical Society 133 (27), 10434-10447, 2011
462011
Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases
K Bum-Erdene, D Liu, G Gonzalez-Gutierrez, MK Ghozayel, D Xu, ...
Proceedings of the National Academy of Sciences 117 (13), 7131-7139, 2020
312020
A new class of orthosteric uPAR· uPA small-molecule antagonists are allosteric inhibitors of the uPAR· vitronectin interaction
D Liu, D Zhou, B Wang, WE Knabe, SO Meroueh
ACS chemical biology 10 (6), 1521-1534, 2015
282015
Small-molecule CaVα1⋅ CaVβ antagonist suppresses neuronal voltage-gated calcium-channel trafficking
X Chen, D Liu, D Zhou, Y Si, D Xu, CW Stamatkin, MK Ghozayel, ...
Proceedings of the National Academy of Sciences 115 (45), E10566-E10575, 2018
262018
Probing Binding and Cellular Activity of Pyrrolidinone and Piperidinone Small Molecules Targeting the Urokinase Receptor
SOM Timmy Mani, Degang Liu, Donghui Zhou, Liwei Li, William Eric Knabe, Fang ...
CHEMMEDCHEM 8 (12), 1963-1977, 2013
252013
Pharmacological inhibition of noncanonical EED-EZH2 signaling overcomes chemoresistance in prostate cancer
X Li, L Gera, S Zhang, Y Chen, L Lou, LM Wilson, ZR Xie, G Sautto, D Liu, ...
Theranostics 11 (14), 6873, 2021
232021
Small molecules engage hot spots through cooperative binding to inhibit a tight protein–protein interaction
D Liu, D Xu, M Liu, WE Knabe, C Yuan, D Zhou, M Huang, SO Meroueh
Biochemistry 56 (12), 1768-1784, 2017
202017
Synthesis and biological evaluation of novel steroid-linked nitrogen mustards
HB Zhang, JJ Xue, XL Zhao, DG Liu, Y Li
Chinese Chemical Letters 20 (6), 680-683, 2009
172009
Small molecules inhibit STAT3 activation, autophagy, and cancer cell anchorage-independent growth
D Zhou, MZ Springer, D Xu, D Liu, A Hudmon, KF Macleod, SO Meroueh
Bioorganic & medicinal chemistry 25 (12), 2995-3005, 2017
102017
Formal total synthesis of benzylpedamide: The right half of (+)-pederin
D Liu, J Xue, Z Xie, L Wei, X Zhang, Y Li
Synlett 2008 (10), 1526-1528, 2008
102008
Structure‐based target‐specific screening leads to small‐molecule CaMKII inhibitors
D Xu, L Li, D Zhou, D Liu, A Hudmon, SO Meroueh
ChemMedChem 12 (9), 660-677, 2017
92017
Design and synthesis of fragment derivatives with a unique inhibition mechanism of the uPAR· uPA interaction
K Bum-Erdene, D Liu, D Xu, MK Ghozayel, SO Meroueh
ACS Medicinal Chemistry Letters 12 (1), 60-66, 2020
82020
Indications of 5′ to 3′ interbase electron transfer as the first step of pyrimidine dimer formation probed by a dinucleotide analog
Y Jian, E Maximowitsch, D Liu, S Adhikari, L Li, T Domratcheva
Chemistry–A European Journal 23 (31), 7526-7537, 2017
82017
Small molecules inhibit ex vivo tumor growth in bone
D Zhou, K Bum-Erdene, D Xu, D Liu, D Tompkins, RS Sulaiman, ...
Bioorganic & Medicinal Chemistry 26 (23-24), 6128-6134, 2018
32018
Asymmetric synthesis of pedamide using I2-induced heterocyclization to construct the skeleton
DG Liu, JJ Xue, ZX Xie, LP Wei, HB Zhang, Y Li
Chinese Chemical Letters 20 (7), 775-778, 2009
22009
Covalent Fragment Inhibits RhoA Activation by Guanine Exchange Factors
MS Hussain, D Liu, WJ Alilain, SO Meroueh
ACS Chemical Neuroscience 14 (14), 2509-2516, 2023
12023
Mimicking Native Interactions for Small-Molecule Inhibitors of Tight Protein-Protein Interactions
D Xu, K Bum-Erdene, Y Si, D Zhou, D Liu, M Ghozayel, S Meroueh
Journal of chemical information and modeling 57 (9), 2250, 2017
2017
Structure-activity study of a new class of inhibitors of the uPAR-uPA protein-protein interaction that impair breast cancer cell invasion
D Liu, T Mani, M Khanna, S Meroueh
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 246, 2013
2013
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