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Patrick Aouad
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The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche
D Ataca, P Aouad, C Constantin, C Laszlo, M Beleut, M Shamseddin, ...
Nature communications 11 (1), 1571, 2020
412020
Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium
S Cagnet, D Ataca, G Sflomos, P Aouad, S Schuepbach-Mallepell, ...
Nature communications 9 (1), 4723, 2018
352018
Mechanism of action of the atypical retinoid ST1926 in colorectal cancer: DNA damage and DNA polymerase α
R Abdel-Samad, P Aouad, H Gali-Muhtasib, Z Sweidan, R Hmadi, ...
American journal of cancer research 8 (1), 39, 2018
352018
Intraductal patient‐derived xenografts of estrogen receptor α‐positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions
M Fiche, V Scabia, P Aouad, L Battista, A Treboux, A Stravodimou, ...
The Journal of pathology 247 (3), 287-292, 2019
342019
Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1
G Sflomos, L Battista, P Aouad, F De Martino, V Scabia, A Stravodimou, ...
EMBO Molecular Medicine 13 (3), e13180, 2021
322021
Antitumor activities of the synthetic retinoid ST1926 in two-dimensional and three-dimensional human breast cancer models
P Aouad, M Saikali, R Abdel-Samad, S Fostok, L El-Houjeiri, C Pisano, ...
Anti-Cancer Drugs 28 (7), 757-770, 2017
312017
Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence
P Aouad, Y Zhang, F De Martino, C Stibolt, S Ali, G Ambrosini, SA Mani, ...
Nature communications 13 (1), 4975, 2022
24*2022
Role of systems biology in brain injury biomarker discovery: neuroproteomics application
Z Jaber, P Aouad, M Al Medawar, H Bahmad, H Abou-Abbass, ...
Injury Models of the Central Nervous System: Methods and Protocols, 157-174, 2016
142016
Antitumor effect of the atypical retinoid ST1926 in acute myeloid leukemia and nanoparticle formulation prolongs lifespan and reduces tumor burden of xenograft mice
L El-Houjeiri, W Saad, B Hayar, P Aouad, N Tawil, R Abdel-Samad, ...
Molecular Cancer Therapeutics 16 (10), 2047-2057, 2017
132017
Natural and synthetic retinoids in preclinical colorectal cancer models
R Abdel-Samad, P Aouad, N Darwiche
Anti-Cancer Drugs 30 (7), 655-669, 2019
92019
Application of systems biology to neuroproteomics: the path to enhanced theranostics in traumatic brain injury
Z Jaber, P Aouad, M Al Medawar, H Bahmad, H Abou-Abbass, F Kobeissy
Injury Models of the Central Nervous System: Methods and Protocols, 139-155, 2016
72016
An engineered multicellular stem cell niche for the 3D derivation of human myogenic progenitors from iPSCs
O Mashinchian, F De Franceschi, S Nassiri, J Michaud, E Migliavacca, ...
The EMBO Journal 41 (14), e110655, 2022
32022
Tumor dormancy: EMT beyond invasion and metastasis
P Aouad, HM Quinn, A Berger, C Brisken
genesis 62 (1), e23552, 2024
22024
Translational screening platform to evaluate chemotherapy in combination with focal therapy for retinoblastoma
IL Sinenko, F Kuttler, V Simeonov, A Moulin, P Aouad, C Stathopoulos, ...
Cancer Science 114 (9), 3728-3739, 2023
12023
Therapeutic targeting of the pentose phosphate pathway in colorectal cancer
N Ghanem, C El Baba, L Al Saleh, B Hayar, P Aouad, M Al Hassan, ...
Cancer Research 80 (16_Supplement), 236-236, 2020
12020
Abstract PO5-14-06: Transcriptomics-based drug screening in 3D ex vivo patient-drived breast cancer model and patient biopsy for personalized therapy
Y Zhang, CHV Ronchi, G Ambrosini, Y Liu, P Aouad, D Matvienko, ...
Cancer Research 84 (9_Supplement), PO5-14-06-PO5-14-06, 2024
2024
Intraductal xenografts model ERα-positive invasive lobular carcinoma of the breast
G Sflomos, L Battista, P Aouad, F De Martino, V Scabia, A Stravodimou, ...
Cancer Research 81 (13_Supplement), 2993-2993, 2021
2021
Intraductal xenografts model estrogen receptor-positive (ER+) breast cancer dormancy and reveal a critical role for epithelial-mesenchymal transition (EMT) in its establishment
P Aouad
EPFL, 2021
2021
Encapsulation of the atypical retinoid ST1926 in nanoparticles prolongs the survival of acute myeloid leukemia xenografted mice at multiple folds lower concentrations than the …
L El-Houjeiri, W Saad, B Hayar, P Aouad, N Tawil, R Abdel-Samad, ...
Cancer Research 77 (13_Supplement), 5140-5140, 2017
2017
Antitumor activities of natural and synthetic retinoids in 2D and 3D human breast cancer models
PA Aouad
Theses, Dissertations, and Projects, 2016
2016
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