The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche D Ataca, P Aouad, C Constantin, C Laszlo, M Beleut, M Shamseddin, ... Nature communications 11 (1), 1571, 2020 | 41 | 2020 |
Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium S Cagnet, D Ataca, G Sflomos, P Aouad, S Schuepbach-Mallepell, ... Nature communications 9 (1), 4723, 2018 | 35 | 2018 |
Mechanism of action of the atypical retinoid ST1926 in colorectal cancer: DNA damage and DNA polymerase α R Abdel-Samad, P Aouad, H Gali-Muhtasib, Z Sweidan, R Hmadi, ... American journal of cancer research 8 (1), 39, 2018 | 35 | 2018 |
Intraductal patient‐derived xenografts of estrogen receptor α‐positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions M Fiche, V Scabia, P Aouad, L Battista, A Treboux, A Stravodimou, ... The Journal of pathology 247 (3), 287-292, 2019 | 34 | 2019 |
Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1 G Sflomos, L Battista, P Aouad, F De Martino, V Scabia, A Stravodimou, ... EMBO Molecular Medicine 13 (3), e13180, 2021 | 32 | 2021 |
Antitumor activities of the synthetic retinoid ST1926 in two-dimensional and three-dimensional human breast cancer models P Aouad, M Saikali, R Abdel-Samad, S Fostok, L El-Houjeiri, C Pisano, ... Anti-Cancer Drugs 28 (7), 757-770, 2017 | 31 | 2017 |
Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence P Aouad, Y Zhang, F De Martino, C Stibolt, S Ali, G Ambrosini, SA Mani, ... Nature communications 13 (1), 4975, 2022 | 24* | 2022 |
Role of systems biology in brain injury biomarker discovery: neuroproteomics application Z Jaber, P Aouad, M Al Medawar, H Bahmad, H Abou-Abbass, ... Injury Models of the Central Nervous System: Methods and Protocols, 157-174, 2016 | 14 | 2016 |
Antitumor effect of the atypical retinoid ST1926 in acute myeloid leukemia and nanoparticle formulation prolongs lifespan and reduces tumor burden of xenograft mice L El-Houjeiri, W Saad, B Hayar, P Aouad, N Tawil, R Abdel-Samad, ... Molecular Cancer Therapeutics 16 (10), 2047-2057, 2017 | 13 | 2017 |
Natural and synthetic retinoids in preclinical colorectal cancer models R Abdel-Samad, P Aouad, N Darwiche Anti-Cancer Drugs 30 (7), 655-669, 2019 | 9 | 2019 |
Application of systems biology to neuroproteomics: the path to enhanced theranostics in traumatic brain injury Z Jaber, P Aouad, M Al Medawar, H Bahmad, H Abou-Abbass, F Kobeissy Injury Models of the Central Nervous System: Methods and Protocols, 139-155, 2016 | 7 | 2016 |
An engineered multicellular stem cell niche for the 3D derivation of human myogenic progenitors from iPSCs O Mashinchian, F De Franceschi, S Nassiri, J Michaud, E Migliavacca, ... The EMBO Journal 41 (14), e110655, 2022 | 3 | 2022 |
Tumor dormancy: EMT beyond invasion and metastasis P Aouad, HM Quinn, A Berger, C Brisken genesis 62 (1), e23552, 2024 | 2 | 2024 |
Translational screening platform to evaluate chemotherapy in combination with focal therapy for retinoblastoma IL Sinenko, F Kuttler, V Simeonov, A Moulin, P Aouad, C Stathopoulos, ... Cancer Science 114 (9), 3728-3739, 2023 | 1 | 2023 |
Therapeutic targeting of the pentose phosphate pathway in colorectal cancer N Ghanem, C El Baba, L Al Saleh, B Hayar, P Aouad, M Al Hassan, ... Cancer Research 80 (16_Supplement), 236-236, 2020 | 1 | 2020 |
Abstract PO5-14-06: Transcriptomics-based drug screening in 3D ex vivo patient-drived breast cancer model and patient biopsy for personalized therapy Y Zhang, CHV Ronchi, G Ambrosini, Y Liu, P Aouad, D Matvienko, ... Cancer Research 84 (9_Supplement), PO5-14-06-PO5-14-06, 2024 | | 2024 |
Intraductal xenografts model ERα-positive invasive lobular carcinoma of the breast G Sflomos, L Battista, P Aouad, F De Martino, V Scabia, A Stravodimou, ... Cancer Research 81 (13_Supplement), 2993-2993, 2021 | | 2021 |
Intraductal xenografts model estrogen receptor-positive (ER+) breast cancer dormancy and reveal a critical role for epithelial-mesenchymal transition (EMT) in its establishment P Aouad EPFL, 2021 | | 2021 |
Encapsulation of the atypical retinoid ST1926 in nanoparticles prolongs the survival of acute myeloid leukemia xenografted mice at multiple folds lower concentrations than the … L El-Houjeiri, W Saad, B Hayar, P Aouad, N Tawil, R Abdel-Samad, ... Cancer Research 77 (13_Supplement), 5140-5140, 2017 | | 2017 |
Antitumor activities of natural and synthetic retinoids in 2D and 3D human breast cancer models PA Aouad Theses, Dissertations, and Projects, 2016 | | 2016 |