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Efficient integration of heterogeneous single-cell transcriptomes using Scanorama B Hie, B Bryson, B Berger Nature biotechnology 37 (6), 685-691, 2019 | 625 | 2019 |
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling SR Floyd, ME Pacold, Q Huang, SM Clarke, FC Lam, IG Cannell, ... Nature 498 (7453), 246-250, 2013 | 338 | 2013 |
Variability in tuberculosis granuloma T cell responses exists, but a balance of pro-and anti-inflammatory cytokines is associated with sterilization HP Gideon, JY Phuah, AJ Myers, BD Bryson, MA Rodgers, MT Coleman, ... PLoS pathogens 11 (1), e1004603, 2015 | 320 | 2015 |
Learning the language of viral evolution and escape B Hie, ED Zhong, B Berger, B Bryson Science 371 (6526), 284-288, 2021 | 230 | 2021 |
Predicting the mutational drivers of future SARS-CoV-2 variants of concern MC Maher, I Bartha, S Weaver, J Di Iulio, E Ferri, L Soriaga, FA Lempp, ... Science translational medicine 14 (633), eabk3445, 2022 | 128 | 2022 |
Leveraging uncertainty in machine learning accelerates biological discovery and design B Hie, BD Bryson, B Berger Cell systems 11 (5), 461-477. e9, 2020 | 121 | 2020 |
Geometric sketching compactly summarizes the single-cell transcriptomic landscape B Hie, H Cho, B DeMeo, B Bryson, B Berger Cell systems 8 (6), 483-493. e7, 2019 | 105 | 2019 |
SirT1 is required in the male germ cell for differentiation and fecundity in mice EL Bell, I Nagamori, EO Williams, AM Del Rosario, BD Bryson, N Watson, ... Development 141 (18), 3495-3504, 2014 | 105 | 2014 |
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control HP Gideon, TK Hughes, CN Tzouanas, MH Wadsworth, AA Tu, ... Immunity 55 (5), 827-846. e10, 2022 | 99 | 2022 |
Molecular characterization of EGFR and EGFRvIII signaling networks in human glioblastoma tumor xenografts H Johnson, AM Del Rosario, BD Bryson, MA Schroeder, JN Sarkaria, ... Molecular & Cellular Proteomics 11 (12), 1724-1740, 2012 | 96 | 2012 |
Computational methods for single-cell RNA sequencing B Hie, J Peters, SK Nyquist, AK Shalek, B Berger, BD Bryson Annual Review of Biomedical Data Science 3, 339-364, 2020 | 91 | 2020 |
Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis BD Bryson, TR Rosebrock, FG Tafesse, CY Itoh, A Nibasumba, ... Nature communications 10 (1), 2329, 2019 | 80 | 2019 |
Posttranslational modification of a histone-like protein regulates phenotypic resistance to isoniazid in mycobacteria A Sakatos, GH Babunovic, MR Chase, A Dills, J Leszyk, T Rosebrock, ... Science advances 4 (5), eaao1478, 2018 | 65 | 2018 |
The cellular architecture of the antimicrobial response network in human leprosy granulomas F Ma, TK Hughes, RMB Teles, PR Andrade, BJ de Andrade Silva, ... Nature immunology 22 (7), 839-850, 2021 | 55 | 2021 |
Dual RNA-Seq of human leprosy lesions identifies bacterial determinants linked to host immune response DJ Montoya, P Andrade, BJA Silva, RMB Teles, F Ma, B Bryson, ... Cell reports 26 (13), 3574-3585. e3, 2019 | 47 | 2019 |
TREM2 macrophages induced by human lipids drive inflammation in acne lesions TH Do, F Ma, PR Andrade, R Teles, BJ de Andrade Silva, C Hu, ... Science immunology 7 (73), eabo2787, 2022 | 44 | 2022 |
Contrastive learning in protein language space predicts interactions between drugs and protein targets R Singh, S Sledzieski, B Bryson, L Cowen, B Berger Proceedings of the National Academy of Sciences 120 (24), e2220778120, 2023 | 34 | 2023 |
Computer aided manual validation of mass spectrometry-based proteomic data TG Curran, BD Bryson, M Reigelhaupt, H Johnson, FM White Methods 61 (3), 219-226, 2013 | 34 | 2013 |
Panoramic stitching of heterogeneous single-cell transcriptomic data B Hie, B Bryson, B Berger BioRxiv, 371179, 2018 | 31 | 2018 |