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Santosh Peddi
Santosh Peddi
Seagen Inc.
Verified email at usc.edu
Title
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Cited by
Year
Thiazole–aminopiperidine hybrid analogues: Design and synthesis of novel Mycobacterium tuberculosis GyrB inhibitors
VU Jeankumar, J Renuka, P Santosh, V Soni, JP Sridevi, P Suryadevara, ...
European journal of medicinal chemistry 70, 143-153, 2013
842013
Ligand-controlled regioselective copper-catalyzed trifluoromethylation to generate (trifluoromethyl) allenes
BR Ambler, S Peddi, RA Altman
Organic letters 17 (10), 2506-2509, 2015
462015
Identification and structure–activity relationship study of carvacrol derivatives as Mycobacterium tuberculosis chorismate mutase inhibitors
R Alokam, VU Jeankumar, JP Sridevi, SS Matikonda, S Peddi, M Alvala, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 29 (4), 547-554, 2014
462014
Discovery and Structure Optimization of a Series of Isatin Derivatives as Mycobacterium tuberculosis Chorismate Mutase Inhibitors
VU Jeankumar, R Alokam, JP Sridevi, P Suryadevara, SS Matikonda, ...
Chemical biology & drug design 83 (4), 498-506, 2014
372014
Bifunctional elastin-like polypeptide nanoparticles bind rapamycin and integrins and suppress tumor growth in vivo
JP Dhandhukia, P Shi, S Peddi, Z Li, S Aluri, Y Ju, D Brill, W Wang, ...
Bioconjugate chemistry 28 (11), 2715-2728, 2017
352017
Copper-catalyzed radical bis (trifluoromethylation) of alkynes and 1, 3-enynes
H Shen, H Xiao, L Zhu, C Li
Synlett 31 (01), 41-44, 2020
302020
Nanotoxicology of an elastin-like polypeptide rapamycin formulation for breast cancer
S Peddi, SK Roberts, JA MacKay
Biomacromolecules 21 (3), 1091-1102, 2020
222020
The humanin peptide mediates ELP nanoassembly and protects human retinal pigment epithelial cells from oxidative stress
Z Li, PG Sreekumar, S Peddi, DR Hinton, R Kannan, JA MacKay
Nanomedicine: Nanotechnology, Biology and Medicine 24, 102111, 2020
192020
Intracellular delivery of Rapamycin from FKBP elastin-like polypeptides is consistent with macropinocytosis
S Peddi, X Pan, JA MacKay
Frontiers in pharmacology 9, 1184, 2018
182018
Berunda polypeptides: multi-headed fusion proteins promote subcutaneous administration of rapamycin to breast cancer in vivo
JP Dhandhukia, Z Li, S Peddi, S Kakan, A Mehta, D Tyrpak, J Despanie, ...
Theranostics 7 (16), 3856, 2017
182017
Copper-catalyzed decarboxylative trifluoromethylation of propargyl bromodifluoroacetates
BR Ambler, S Peddi, RA Altman
Synthesis, 1938-1946, 2014
152014
Berunda polypeptides: biheaded rapamycin carriers for subcutaneous treatment of autoimmune dry eye disease
C Lee, H Guo, W Klinngam, SR Janga, F Yarber, S Peddi, MC Edman, ...
Molecular pharmaceutics 16 (7), 3024-3039, 2019
142019
Adaptable antibody Nanoworms designed for non-Hodgkin lymphoma
C Lee, S Peddi, C Anderson, H Su, H Cui, AL Epstein, JA MacKay
Biomaterials 262, 120338, 2020
102020
Molecular targeting of immunosuppressants using a bifunctional elastin-like polypeptide
Y Ju, H Guo, F Yarber, MC Edman, S Peddi, SR Janga, JA MacKay, ...
Bioconjugate chemistry 30 (9), 2358-2372, 2019
102019
Intralacrimal Sustained Delivery of Rapamycin Shows Therapeutic Effects without Systemic Toxicity in a Mouse Model of Autoimmune Dacryoadenitis Characteristic of Sjögren’s …
Y Ju, MC Edman, H Guo, SR Janga, S Peddi, SG Louie, JA Junge, ...
Biomacromolecules 22 (3), 1102-1114, 2020
72020
Multimeric elastin-like polypeptides
JA MacKay, M Shah, SF Hamm-Alvarez, H Guo, S Peddi
US Patent 11,464,867, 2022
42022
Hydra-Elastin-like polypeptides increase rapamycin potency when targeting cell surface GRP78
H Avila, J Yu, G Boddu, A Phan, A Truong, S Peddi, H Guo, SJ Lee, ...
Biomacromolecules 23 (8), 3116-3129, 2022
42022
Berunda Polypeptides Carrying Rapalogues Inhibit Tumor mTORC1 Better than Oral Everolimus
S Peddi, JA MacKay
Biomacromolecules 21 (8), 3038-3046, 2020
32020
Protein polymer fusions for subcutaneous delivery of small molecules
JA MacKay, JP Dhandhukia, S Peddi, SK Roberts
US Patent App. 16/306,825, 2019
22019
Multimeric elastin-like polypeptides
JA MacKay, M Shah, SF Hamm-Alvarez, H Guo, S Peddi
US Patent App. 17/963,037, 2023
2023
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