Follow
Brenna C Novotny
Brenna C Novotny
Bioinformatician, Mayo Clinic
Verified email at mayo.edu
Title
Cited by
Cited by
Year
TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4
M Gratuze, JCM Schlachetzki, RDO Albanus, N Jain, B Novotny, L Brase, ...
Neuron 111 (2), 202-219. e7, 2023
392023
An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology
PW Sheehan, CJ Nadarajah, MF Kanan, JN Patterson, B Novotny, ...
Neuron 111 (15), 2383-2398. e7, 2023
252023
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers
L Brase, SF You, R D’Oliveira Albanus, JL Del-Aguila, Y Dai, BC Novotny, ...
Nature communications 14 (1), 2314, 2023
242023
Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer’s disease
YJ Sung, C Yang, J Norton, M Johnson, A Fagan, RJ Bateman, RJ Perrin, ...
Science translational medicine 15 (703), eabq5923, 2023
172023
Metabolomic and lipidomic signatures in autosomal dominant and late‐onset Alzheimer's disease brains
BC Novotny, MV Fernandez, C Wang, JP Budde, K Bergmann, ...
Alzheimer's & Dementia 19 (5), 1785-1799, 2023
162023
A landscape of the genetic and cellular heterogeneity in Alzheimer disease
L Brase, SF You, RDO Albanus, JL Del-Aguila, Y Dai, BC Novotny, ...
Medrxiv, 2021.11. 30.21267072, 2021
112021
Multi-tissue proteomics identifies molecular signatures for sporadic and genetically defined Alzheimer disease cases
C Cruchaga, YJ Sung, C Yang, F Wang, A Suhy, J Norton, B Novotny, ...
32021
Systematic analysis of cellular crosstalk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer’s disease
RD Albanus, GM Finan, L Brase, S Chen, Q Guo, A Kannan, M Acquarone, ...
22022
Multi‐omics data integration reveals clinically meaningful molecular profiles of Alzheimer disease
AM Eteleeb, BC Novotny, JC Morris, RJ Bateman, RJ Perrin, CM Karch, ...
Alzheimer's & Dementia 17, e052942, 2021
22021
Identification of genetic regulators of human metabolites in CSF
C Wang, S Mafimoghaddam, BC Novotny, YJ Sung, FHG Farias, C Yang, ...
Alzheimer's & Dementia 19, e064147, 2023
12023
Profiling the metabolic landscape of AD
BC Novotny, V Fernandez, JP Budde, K Bergmann, JC Morris, ...
Alzheimer's & Dementia 17, e050086, 2021
12021
Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer’s disease
AM Eteleeb, BC Novotny, CS Tarraga, C Sohn, E Dhungel, L Brase, ...
PLoS biology 22 (4), e3002607, 2024
2024
Generating clinical-grade pathology reports from gigapixel whole slide images with HistoGPT
M Tran, P Schmidle, SJ Wagner, V Koch, B Novotny, V Lupperger, ...
medRxiv, 2024.03. 15.24304211, 2024
2024
Ambient RNA from CSF to capture brain cell‐type signatures in AD and other neurodegenerative diseases
J Kaczaral, J Buss, A Eteleeb, BC Novotny, R D'Oliveira Albanus, L Brase, ...
Alzheimer's & Dementia 19, e077297, 2023
2023
Cross‐omics integration analysis revels synaptic dysregulation across brain regions at later stages of Alzheimer disease
AM Eteleeb, BC Novotny, C Soriano‐Tarraga, C Sohn, E Dhungel, ...
Alzheimer's & Dementia 19, e077100, 2023
2023
Microglia transcriptional heterogeneity across human and experimental models
A Garg, BC Novotny, R D'Oliveira Albanus, L Brase, CM Karch, JC Morris, ...
Alzheimer's & Dementia 19, e076619, 2023
2023
Brain cross-omics integration in Alzheimer’s disease
AM Eteleeb, BC Novotny, CS Tarraga, C Sohn, E Dhungel, L Brase, ...
medRxiv, 2022.12. 10.22283295, 2022
2022
Genetic and glial heterogeneity in Alzheimer disease
L Brase, SF You, BC Novotny, C Soriano‐Tarraga, JC Morris, RJ Bateman, ...
Alzheimer's & Dementia 18, e061185, 2022
2022
Systematic characterization of brain cellular crosstalk signaling networks in Alzheimer’s disease reveals a novel role for SEMA6D in TREM2-dependent microglial activation
RDO Albanus, GM Finan, L Brase, S Chen, Q Guo, A Kannan, ...
bioRxiv, 2022.11. 11.516215, 2022
2022
Genome‐wide scan of Alzheimer disease cohort identifies genetic loci associated with human brain metabolite levels
C Wang, FHG Farias, BC Novotny, C Yang, F Wang, V Fernandez, ...
Alzheimer's & Dementia 17, e051756, 2021
2021
The system can't perform the operation now. Try again later.
Articles 1–20