TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4 M Gratuze, JCM Schlachetzki, RDO Albanus, N Jain, B Novotny, L Brase, ... Neuron 111 (2), 202-219. e7, 2023 | 39 | 2023 |
An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology PW Sheehan, CJ Nadarajah, MF Kanan, JN Patterson, B Novotny, ... Neuron 111 (15), 2383-2398. e7, 2023 | 25 | 2023 |
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers L Brase, SF You, R D’Oliveira Albanus, JL Del-Aguila, Y Dai, BC Novotny, ... Nature communications 14 (1), 2314, 2023 | 24 | 2023 |
Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer’s disease YJ Sung, C Yang, J Norton, M Johnson, A Fagan, RJ Bateman, RJ Perrin, ... Science translational medicine 15 (703), eabq5923, 2023 | 17 | 2023 |
Metabolomic and lipidomic signatures in autosomal dominant and late‐onset Alzheimer's disease brains BC Novotny, MV Fernandez, C Wang, JP Budde, K Bergmann, ... Alzheimer's & Dementia 19 (5), 1785-1799, 2023 | 16 | 2023 |
A landscape of the genetic and cellular heterogeneity in Alzheimer disease L Brase, SF You, RDO Albanus, JL Del-Aguila, Y Dai, BC Novotny, ... Medrxiv, 2021.11. 30.21267072, 2021 | 11 | 2021 |
Multi-tissue proteomics identifies molecular signatures for sporadic and genetically defined Alzheimer disease cases C Cruchaga, YJ Sung, C Yang, F Wang, A Suhy, J Norton, B Novotny, ... | 3 | 2021 |
Systematic analysis of cellular crosstalk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer’s disease RD Albanus, GM Finan, L Brase, S Chen, Q Guo, A Kannan, M Acquarone, ... | 2 | 2022 |
Multi‐omics data integration reveals clinically meaningful molecular profiles of Alzheimer disease AM Eteleeb, BC Novotny, JC Morris, RJ Bateman, RJ Perrin, CM Karch, ... Alzheimer's & Dementia 17, e052942, 2021 | 2 | 2021 |
Identification of genetic regulators of human metabolites in CSF C Wang, S Mafimoghaddam, BC Novotny, YJ Sung, FHG Farias, C Yang, ... Alzheimer's & Dementia 19, e064147, 2023 | 1 | 2023 |
Profiling the metabolic landscape of AD BC Novotny, V Fernandez, JP Budde, K Bergmann, JC Morris, ... Alzheimer's & Dementia 17, e050086, 2021 | 1 | 2021 |
Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer’s disease AM Eteleeb, BC Novotny, CS Tarraga, C Sohn, E Dhungel, L Brase, ... PLoS biology 22 (4), e3002607, 2024 | | 2024 |
Generating clinical-grade pathology reports from gigapixel whole slide images with HistoGPT M Tran, P Schmidle, SJ Wagner, V Koch, B Novotny, V Lupperger, ... medRxiv, 2024.03. 15.24304211, 2024 | | 2024 |
Ambient RNA from CSF to capture brain cell‐type signatures in AD and other neurodegenerative diseases J Kaczaral, J Buss, A Eteleeb, BC Novotny, R D'Oliveira Albanus, L Brase, ... Alzheimer's & Dementia 19, e077297, 2023 | | 2023 |
Cross‐omics integration analysis revels synaptic dysregulation across brain regions at later stages of Alzheimer disease AM Eteleeb, BC Novotny, C Soriano‐Tarraga, C Sohn, E Dhungel, ... Alzheimer's & Dementia 19, e077100, 2023 | | 2023 |
Microglia transcriptional heterogeneity across human and experimental models A Garg, BC Novotny, R D'Oliveira Albanus, L Brase, CM Karch, JC Morris, ... Alzheimer's & Dementia 19, e076619, 2023 | | 2023 |
Brain cross-omics integration in Alzheimer’s disease AM Eteleeb, BC Novotny, CS Tarraga, C Sohn, E Dhungel, L Brase, ... medRxiv, 2022.12. 10.22283295, 2022 | | 2022 |
Genetic and glial heterogeneity in Alzheimer disease L Brase, SF You, BC Novotny, C Soriano‐Tarraga, JC Morris, RJ Bateman, ... Alzheimer's & Dementia 18, e061185, 2022 | | 2022 |
Systematic characterization of brain cellular crosstalk signaling networks in Alzheimer’s disease reveals a novel role for SEMA6D in TREM2-dependent microglial activation RDO Albanus, GM Finan, L Brase, S Chen, Q Guo, A Kannan, ... bioRxiv, 2022.11. 11.516215, 2022 | | 2022 |
Genome‐wide scan of Alzheimer disease cohort identifies genetic loci associated with human brain metabolite levels C Wang, FHG Farias, BC Novotny, C Yang, F Wang, V Fernandez, ... Alzheimer's & Dementia 17, e051756, 2021 | | 2021 |