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Alexander I Taylor
Alexander I Taylor
Sir Henry Dale Fellow, Lecturer in Chemical Biology (proleptic), King's College London
Verified email at kcl.ac.uk
Title
Cited by
Cited by
Year
Synthetic genetic polymers capable of heredity and evolution
VB Pinheiro, AI Taylor, C Cozens, M Abramov, M Renders, S Zhang, ...
Science 336 (6079), 341-344, 2012
7682012
Catalysts from synthetic genetic polymers
AI Taylor, VB Pinheiro, MJ Smola, AS Morgunov, S Peak-Chew, C Cozens, ...
Nature 518 (7539), 427-430, 2015
2882015
A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids
S Arangundy-Franklin, AI Taylor, BT Porebski, V Genna, S Peak-Chew, ...
Nature chemistry 11 (6), 533-542, 2019
802019
The crystal structure of an avian IgY-Fc fragment reveals conservation with both mammalian IgG and IgE
AI Taylor, SM Fabiane, BJ Sutton, RA Calvert
Biochemistry 48 (3), 558-562, 2009
722009
Avian IgY binds to a monocyte receptor with IgG-like kinetics despite an IgE-like structure
AI Taylor, HJ Gould, BJ Sutton, RA Calvert
Journal of Biological Chemistry 283 (24), 16384-16390, 2008
652008
Nanostructures from synthetic genetic polymers
AI Taylor, F Beuron, SY Peak‐Chew, EP Morris, P Herdewijn, P Holliger
ChemBioChem 17 (12), 1107-1110, 2016
612016
Directed evolution of artificial enzymes (XNAzymes) from diverse repertoires of synthetic genetic polymers
AI Taylor, P Holliger
Nature Protocols 10 (10), 1625-1642, 2015
542015
Discovery and evolution of RNA and XNA reverse transcriptase function and fidelity
G Houlihan, S Arangundy-Franklin, BT Porebski, N Subramanian, ...
Nature chemistry 12 (8), 683-690, 2020
502020
Towards applications of synthetic genetic polymers in diagnosis and therapy
AI Taylor, S Arangundy-Franklin, P Holliger
Current Opinion in Chemical Biology 22, 79-84, 2014
492014
Random-sequence genetic oligomer pools display an innate potential for ligation and recombination
H Mutschler, AI Taylor, BT Porebski, A Lightowlers, G Houlihan, ...
Elife 7, e43022, 2018
422018
Beyond DNA and RNA: the expanding toolbox of synthetic genetics
AI Taylor, G Houlihan, P Holliger
Cold Spring Harbor perspectives in biology 11 (6), a032490, 2019
372019
The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL
AI Taylor, HJ Gould, BJ Sutton, RA Calvert
Immunogenetics 59, 323-328, 2007
302007
A modular XNAzyme cleaves long, structured RNAs under physiological conditions and enables allele-specific gene silencing
AI Taylor, CJK Wan, MJ Donde, SY Peak-Chew, P Holliger
Nature chemistry 14 (11), 1295-1305, 2022
292022
Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites
AI Taylor, BJ Sutton, RA Calvert
Developmental & Comparative Immunology 34 (2), 97-101, 2010
282010
A monomeric chicken IgY receptor binds IgY with 2: 1 stoichiometry
AI Taylor, RL Beavil, BJ Sutton, RA Calvert
Journal of biological chemistry 284 (36), 24168-24175, 2009
282009
A two-residue nascent-strand steric gate controls synthesis of 2′-O-methyl- and 2′-O-(2-methoxyethyl)-RNA
N Freund, AI Taylor, S Arangundy-Franklin, N Subramanian, ...
Nature chemistry 15 (1), 91-100, 2023
272023
Enzymatic Synthesis of Nucleic Acids with Defined Regioisomeric 2′‐5′ Linkages
C Cozens, H Mutschler, GM Nelson, G Houlihan, AI Taylor, P Holliger
Angewandte Chemie International Edition 54 (51), 15570-15573, 2015
242015
Selecting Fully‐Modified XNA Aptamers Using Synthetic Genetics
AI Taylor, P Holliger
Current protocols in chemical biology 10 (2), e44, 2018
202018
Efficient synthesis and replication of diverse sequence libraries composed of biostable nucleic acid analogues
JRD Hervey, N Freund, G Houlihan, G Dhaliwal, P Holliger, AI Taylor
RSC Chemical Biology 3 (10), 1209-1215, 2022
112022
On gene silencing by the X10-23 DNAzyme
AI Taylor, P Holliger
Nature Chemistry 14 (8), 855-858, 2022
102022
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