| The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans LR Lapierre, CD De Magalhaes Filho, PR McQuary, CC Chu, O Visvikis, ... Nature Communications 4 (1), 2267, 2013 | 469 | 2013 |
| Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans LR Lapierre, S Gelino, A Meléndez, M Hansen Current Biology 21 (18), 1507-1514, 2011 | 360 | 2011 |
| Transcriptional and epigenetic regulation of autophagy in aging LR Lapierre, C Kumsta, M Sandri, A Ballabio, M Hansen Autophagy 11 (6), 867-880, 2015 | 339 | 2015 |
| Lessons from C. elegans: signaling pathways for longevity LR Lapierre, M Hansen Trends in Endocrinology & Metabolism 23 (12), 637-644, 2012 | 335 | 2012 |
| Autophagy in aging and longevity SQ Wong, AV Kumar, J Mills, LR Lapierre Human Genetics 139, 277-290, 2020 | 181 | 2020 |
| Guidelines for monitoring autophagy in Caenorhabditis elegans H Zhang, JT Chang, B Guo, M Hansen, K Jia, AL Kovács, C Kumsta, ... Autophagy 11 (1), 9-27, 2015 | 148 | 2015 |
| Autophagy-mediated longevity is modulated by lipoprotein biogenesis NE Seah, CD de Magalhaes Filho, AP Petrashen, HR Henderson, ... Autophagy 12 (2), 261-272, 2016 | 113 | 2016 |
| Selective autophagy receptor p62/SQSTM1, a pivotal player in stress and aging AV Kumar, J Mills, LR Lapierre Frontiers in cell and developmental biology 10, 793328, 2022 | 100 | 2022 |
| Autophagy genes are required for normal lipid levels in C. elegans LR Lapierre, MJ Silvestrini, L Nunez, K Ames, S Wong, TT Le, M Hansen, ... Autophagy 9 (3), 1-9, 2013 | 86 | 2013 |
| Visible light reduces C. elegans longevity CD De Magalhaes Filho, B Henriquez, NE Seah, RM Evans, LR Lapierre, ... Nature Communications 9 (1), 927, 2018 | 82 | 2018 |
| Nuclear export inhibition enhances HLH-30/TFEB activity, autophagy, and lifespan MJ Silvestrini, JR Johnson, AV Kumar, TG Thakurta, K Blais, ZA Neill, ... Cell Reports 23 (7), 1915-1921, 2018 | 77 | 2018 |
| Emerging topics in C. elegans aging research: Transcriptional regulation, stress response and epigenetics MS Denzel, LR Lapierre, HID Mack Mechanisms of Ageing and Development 177, 4-21, 2019 | 73 | 2019 |
| Autophagy links lipid metabolism to longevity in C. elegans LR Lapierre, A Meléndez, M Hansen Autophagy 8 (1), 144-146, 2012 | 63 | 2012 |
| The AAA-ATPase p97 facilitates degradation of apolipoprotein B by the ubiquitin-proteasome pathway EA Fisher, LR Lapierre, RD Junkins, RS McLeod Journal of Lipid Research 49 (10), 2149-2160, 2008 | 42 | 2008 |
| Attenuated secretion of very low density lipoproteins from McA-RH7777 cells treated with eicosapentaenoic acid is associated with impaired utilization of triacylglycerol … K Tran, F Sun, Z Cui, G Thorne-Tjomsland, CS Germain, LR Lapierre, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2006 | 40 | 2006 |
| A pan-tissue DNA-methylation epigenetic clock based on deep learning LP de Lima Camillo, LR Lapierre, R Singh npj Aging and Mechanisms of Disease 8 (1), 4, 2022 | 34 | 2022 |
| Amino acid sequences within the β1 domain of human apolipoprotein B can mediate rapid intracellular degradation LR Lapierre, DL Currie, Z Yao, J Wang, RS McLeod Journal of Lipid Research 45 (2), 366-377, 2004 | 18 | 2004 |
| C. elegans to model autophagy-related human disorders SQ Wong, AV Kumar, J Mills, LR Lapierre Progress in Molecular Biology and Translational Science 172, 325-373, 2020 | 13 | 2020 |
| Neuronal HLH‐30/TFEB modulates peripheral mitochondrial fragmentation to improve thermoresistance in Caenorhabditis elegans SQ Wong, CJ Ryan, DM Bonal, J Mills, LR Lapierre Aging Cell 22 (3), e13741, 2023 | 8 | 2023 |
| Exportin 1 modulates life span by regulating nucleolar dynamics via the autophagy protein LGG-1/GABARAP AV Kumar, T Kang, TG Thakurta, C Ng, AN Rogers, MR Larsen, ... Science Advances 8 (13), eabj1604, 2022 | 6 | 2022 |
Malene HansenProfessor, Buck Institute for Research on AgingVerified email at buckinstitute.org
