Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer S Raghavan, PS Winter, AW Navia, HL Williams, A DenAdel, KE Lowder, ... Cell 184 (25), 6119-6137. e26, 2021 | 243 | 2021 |
Repeat expansions confer WRN dependence in microsatellite-unstable cancers N van Wietmarschen, S Sridharan, WJ Nathan, A Tubbs, EM Chan, ... Nature 586 (7828), 292-298, 2020 | 113 | 2020 |
Sparse dictionary learning recovers pleiotropy from human cell fitness screens J Pan, JJ Kwon, JA Talamas, AA Borah, F Vazquez, JS Boehm, ... Cell systems 13 (4), 286-303. e10, 2022 | 18 | 2022 |
Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal JM Krill-Burger, JM Dempster, AA Borah, BR Paolella, DE Root, TR Golub, ... Genome Biology 24 (1), 192, 2023 | 13 | 2023 |
A ubiquitination cascade regulating the integrated stress response and survival in carcinomas LD Cervia, T Shibue, AA Borah, B Gaeta, L He, L Leung, N Li, SM Moyer, ... Cancer discovery 13 (3), 766-795, 2023 | 12 | 2023 |
Transcriptional subtype-specific microenvironmental crosstalk and tumor cell plasticity in metastatic pancreatic cancer S Raghavan, PS Winter, AW Navia, HL Williams, A DenAdel, RL Kalekar, ... CANCER RESEARCH 80 (22), 2020 | 7 | 2020 |
The tumor microenvironment drives transcriptional phenotypes and their plasticity in metastatic pancreatic cancer S Raghavan, PS Winter, AW Navia, HL Williams, A DenAdel, RL Kalekar, ... Biorxiv, 2020.08. 25.256214, 2020 | 6 | 2020 |
PELO is a synthetic lethal target in chromosome 9p21-deleted or MSI cancers EM Chan, P Borck, N Bick, K Jankovic, I Boyle, L Parker-Burns, K Foster, ... Cancer Research 84 (6_Supplement), 3364-3364, 2024 | | 2024 |
In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma S John Liu, J Pak, C Zou, T Casey-Clyde, AA Borah, D Wu, K Seo, ... bioRxiv, 2023.09. 01.555831, 2023 | | 2023 |
Systematic methods to identify cancer vulnerabilities from genome-wide loss-of-function screens: An interactive framework for target discovery JM Krill-Burger, AA Borah, BR Paolella, JM McFarland, F Vazquez Cancer Research 82 (12_Supplement), 1897-1897, 2022 | | 2022 |
A ubiquitination cascade regulates the integrated stress response and epithelial cancer survival LD Cervia, T Shibue, B Gaeta, A Borah, L Leung, N Li, N Dumont, ... Cancer Research 81 (13_Supplement), 1950-1950, 2021 | | 2021 |
Abstract PO-058: Transcriptional subtype-specific microenvironmental crosstalk and tumor cell plasticity in metastatic pancreatic cancer S Raghavan, PS Winter, AW Navia, HL Williams, A DenAdel, RL Kalekar, ... Cancer Research 80 (22_Supplement), PO-058-PO-058, 2020 | | 2020 |
Abstract PR03: Subtype-specific microenvironmental crosstalk and tumor cell plasticity in metastatic pancreatic cancer PS Winter, S Raghavan, A Navia, H Williams, A DenAdel, R Kalekar, ... Cancer Research 80 (21_Supplement), PR03-PR03, 2020 | | 2020 |
The role of EGR1 and AP1 in acute myeloid leukemia cell reprogramming toward cell cycle arrest and apoptosis M Roberts, L Kageler, K Bendinelli, S Bonner, A Borah, J Forrester Cancer Research 80 (16_Supplement), 4678-4678, 2020 | | 2020 |
Abstract PR02: Matched metastatic pancreatic ductal adenocarcinoma biopsies and organoid models reveal tumor cell transcriptional plasticity and subtype-specific … PS Winter, S Raghavan, AW Navia, H Williams, J Galvez-Reyes, ... Cancer Research 80 (11_Supplement), PR02-PR02, 2020 | | 2020 |
Matched metastatic pancreatic ductal adenocarcinoma biopsies and organoid models reveal tumor cell transcriptional plasticity and subtype-specific microenvironmental crosstalk. PS Winter, S Raghavan, AW Navia, H Williams, J Galvez-Reyes, ... CANCER RESEARCH 80 (11), 24-25, 2020 | | 2020 |
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