Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance DA Fidock, T Nomura, AK Talley, RA Cooper, SM Dzekunov, MT Ferdig, ... Molecular cell 6 (4), 861-871, 2000 | 1858 | 2000 |
The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes X Su, VM Heatwole, SP Wertheimer, F Guinet, JA Herrfeldt, DS Peterson, ... Cell 82 (1), 89-100, 1995 | 1383 | 1995 |
A molecular marker for chloroquine-resistant falciparum malaria A Djimdé, OK Doumbo, JF Cortese, K Kayentao, S Doumbo, Y Diourté, ... New England journal of medicine 344 (4), 257-263, 2001 | 1271 | 2001 |
Chloroquine-resistant malaria TE Wellems, CV Plowe The Journal of infectious diseases 184 (6), 770-776, 2001 | 1130 | 2001 |
Genetic analysis of the human malaria parasite Plasmodium falciparum D Walliker, IA Quakyi, TE Wellems, TF McCutchan, A Szarfman, ... Science 236 (4809), 1661-1666, 1987 | 881 | 1987 |
Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria. DS Peterson, D Walliker, TE Wellems Proceedings of the National Academy of sciences 85 (23), 9114-9118, 1988 | 798 | 1988 |
Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: polymerase chain reaction methods for surveillance in Africa CV Plowe, A Djimde, M Bouare, O Doumbo, TE Wellems American Journal of Tropical Medicine and Hygiene 52 (6), 565-568, 1995 | 765 | 1995 |
Malaria biology and disease pathogenesis: insights for new treatments LH Miller, HC Ackerman, X Su, TE Wellems Nature medicine 19 (2), 156-167, 2013 | 710 | 2013 |
Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross TE Wellems, LJ Panton, IY Gluzman, VE Do Rosario, RW Gwadz, ... Nature 345 (6272), 253-255, 1990 | 685 | 1990 |
Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparum LH Freitas-Junior, E Bottius, LA Pirrit, KW Deitsch, C Scheidig, F Guinet, ... Nature 407 (6807), 1018-1022, 2000 | 620 | 2000 |
Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil DA Fidock, TE Wellems Proceedings of the National Academy of Sciences 94 (20), 10931-10936, 1997 | 596 | 1997 |
Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria. DS Peterson, WK Milhous, TE Wellems Proceedings of the National Academy of Sciences 87 (8), 3018-3022, 1990 | 546 | 1990 |
Complex polymorphisms in an∼ 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa X Su, LA Kirkman, H Fujioka, TE Wellems Cell 91 (5), 593-603, 1997 | 508 | 1997 |
Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine. Y Wu, LA Kirkman, TE Wellems Proceedings of the National Academy of Sciences 93 (3), 1130-1134, 1996 | 498 | 1996 |
Transfection of Plasmodium falciparum within human red blood cells. Y Wu, CD Sifri, HH Lei, X Su, TE Wellems Proceedings of the National Academy of Sciences 92 (4), 973-977, 1995 | 487 | 1995 |
Plasmodium biology: genomic gleanings L Aravind, LM Iyer, TE Wellems, LH Miller Cell 115 (7), 771-785, 2003 | 438 | 2003 |
Genetic mapping of the chloroquine-resistance locus on Plasmodium falciparum chromosome 7. TE Wellems, A Walker-Jonah, LJ Panton Proceedings of the National Academy of Sciences 88 (8), 3382-3386, 1991 | 435 | 1991 |
A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum X Su, MT Ferdig, Y Huang, CQ Huynh, A Liu, J You, JC Wootton, ... Science 286 (5443), 1351-1353, 1999 | 412 | 1999 |
Secretion of a malarial histidine-rich protein (Pf HRP II) from Plasmodium falciparum-infected erythrocytes. RJ Howard, S Uni, M Aikawa, SB Aley, JH Leech, AM Lew, TE Wellems, ... The Journal of cell biology 103 (4), 1269-1277, 1986 | 412 | 1986 |
The Duffy receptor family of Plasmodium knowlesi is located within the micronemes of invasive malaria merozoites JH Adams, DE Hudson, M Torii, GE Ward, TE Wellems, M Aikawa, ... Cell 63 (1), 141-153, 1990 | 377 | 1990 |