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Thomas Wellems
Thomas Wellems
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Year
Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance
DA Fidock, T Nomura, AK Talley, RA Cooper, SM Dzekunov, MT Ferdig, ...
Molecular cell 6 (4), 861-871, 2000
18582000
The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes
X Su, VM Heatwole, SP Wertheimer, F Guinet, JA Herrfeldt, DS Peterson, ...
Cell 82 (1), 89-100, 1995
13831995
A molecular marker for chloroquine-resistant falciparum malaria
A Djimdé, OK Doumbo, JF Cortese, K Kayentao, S Doumbo, Y Diourté, ...
New England journal of medicine 344 (4), 257-263, 2001
12712001
Chloroquine-resistant malaria
TE Wellems, CV Plowe
The Journal of infectious diseases 184 (6), 770-776, 2001
11302001
Genetic analysis of the human malaria parasite Plasmodium falciparum
D Walliker, IA Quakyi, TE Wellems, TF McCutchan, A Szarfman, ...
Science 236 (4809), 1661-1666, 1987
8811987
Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria.
DS Peterson, D Walliker, TE Wellems
Proceedings of the National Academy of sciences 85 (23), 9114-9118, 1988
7981988
Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: polymerase chain reaction methods for surveillance in Africa
CV Plowe, A Djimde, M Bouare, O Doumbo, TE Wellems
American Journal of Tropical Medicine and Hygiene 52 (6), 565-568, 1995
7651995
Malaria biology and disease pathogenesis: insights for new treatments
LH Miller, HC Ackerman, X Su, TE Wellems
Nature medicine 19 (2), 156-167, 2013
7102013
Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross
TE Wellems, LJ Panton, IY Gluzman, VE Do Rosario, RW Gwadz, ...
Nature 345 (6272), 253-255, 1990
6851990
Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparum
LH Freitas-Junior, E Bottius, LA Pirrit, KW Deitsch, C Scheidig, F Guinet, ...
Nature 407 (6807), 1018-1022, 2000
6202000
Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil
DA Fidock, TE Wellems
Proceedings of the National Academy of Sciences 94 (20), 10931-10936, 1997
5961997
Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria.
DS Peterson, WK Milhous, TE Wellems
Proceedings of the National Academy of Sciences 87 (8), 3018-3022, 1990
5461990
Complex polymorphisms in an∼ 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa
X Su, LA Kirkman, H Fujioka, TE Wellems
Cell 91 (5), 593-603, 1997
5081997
Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine.
Y Wu, LA Kirkman, TE Wellems
Proceedings of the National Academy of Sciences 93 (3), 1130-1134, 1996
4981996
Transfection of Plasmodium falciparum within human red blood cells.
Y Wu, CD Sifri, HH Lei, X Su, TE Wellems
Proceedings of the National Academy of Sciences 92 (4), 973-977, 1995
4871995
Plasmodium biology: genomic gleanings
L Aravind, LM Iyer, TE Wellems, LH Miller
Cell 115 (7), 771-785, 2003
4382003
Genetic mapping of the chloroquine-resistance locus on Plasmodium falciparum chromosome 7.
TE Wellems, A Walker-Jonah, LJ Panton
Proceedings of the National Academy of Sciences 88 (8), 3382-3386, 1991
4351991
A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum
X Su, MT Ferdig, Y Huang, CQ Huynh, A Liu, J You, JC Wootton, ...
Science 286 (5443), 1351-1353, 1999
4121999
Secretion of a malarial histidine-rich protein (Pf HRP II) from Plasmodium falciparum-infected erythrocytes.
RJ Howard, S Uni, M Aikawa, SB Aley, JH Leech, AM Lew, TE Wellems, ...
The Journal of cell biology 103 (4), 1269-1277, 1986
4121986
The Duffy receptor family of Plasmodium knowlesi is located within the micronemes of invasive malaria merozoites
JH Adams, DE Hudson, M Torii, GE Ward, TE Wellems, M Aikawa, ...
Cell 63 (1), 141-153, 1990
3771990
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