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An expanded universe of cancer targets WC Hahn, JS Bader, TP Braun, A Califano, PA Clemons, BJ Druker, ... Cell 184 (5), 1142-1155, 2021 | 153 | 2021 |
Fancd2 −/− mice have hematopoietic defects that can be partially corrected by resveratrol QS Zhang, L Marquez-Loza, L Eaton, AW Duncan, DC Goldman, P Anur, ... Blood, The Journal of the American Society of Hematology 116 (24), 5140-5148, 2010 | 106 | 2010 |
CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells DK Edwards, K Watanabe-Smith, A Rofelty, A Damnernsawad, T Laderas, ... Blood, The Journal of the American Society of Hematology 133 (6), 588-599, 2019 | 96 | 2019 |
The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance SK Joshi, T Nechiporuk, D Bottomly, PD Piehowski, JA Reisz, ... Cancer cell 39 (7), 999-1014. e8, 2021 | 69 | 2021 |
Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms SK Joshi, K Qian, WH Bisson, K Watanabe-Smith, A Huang, D Bottomly, ... Blood, The Journal of the American Society of Hematology 135 (24), 2159-2170, 2020 | 27 | 2020 |
Gain-of-function mutations in granulocyte colony–stimulating factor receptor (CSF3R) reveal distinct mechanisms of CSF3R activation H Zhang, C Coblentz, K Watanabe-Smith, S Means, J Means, JE Maxson, ... Journal of Biological Chemistry 293 (19), 7387-7396, 2018 | 26 | 2018 |
Discovery and functional characterization of a germline, CSF2RB-activating mutation in leukemia K Watanabe-Smith, C Tognon, JW Tyner, JPP Meijerink, BJ Druker, ... Leukemia 30 (9), 1950-1953, 2016 | 25 | 2016 |
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Evaluation of resveratrol and N‐acetylcysteine for cancer chemoprevention in a Fanconi anemia murine model QS Zhang, L Marquez‐Loza, AM Sheehan, K Watanabe‐Smith, L Eaton, ... Pediatric blood & cancer 61 (4), 740-742, 2014 | 21 | 2014 |
Analysis of acquired mutations in transgenes arising in Ba/F3 transformation assays: findings and recommendations K Watanabe-Smith, J Godil, A Agarwal, C Tognon, B Druker Oncotarget 8 (8), 12596, 2017 | 14 | 2017 |
Fancd2 and p21 function independently in maintaining the size of hematopoietic stem and progenitor cell pool in mice QS Zhang, K Watanabe-Smith, K Schubert, A Major, AM Sheehan, ... Stem cell research 11 (2), 687-692, 2013 | 14 | 2013 |
Unpaired extracellular cysteine mutations of CSF3R mediate gain or loss of function H Zhang, S Means, AR Schultz, K Watanabe-Smith, BC Medeiros, ... Cancer research 77 (16), 4258-4267, 2017 | 13 | 2017 |
Genomic markers of midostaurin drug sensitivity in FLT3 mutated and FLT3 wild-type acute myeloid leukemia patients MW Rosenberg, K Watanabe-Smith, JW Tyner, CE Tognon, BJ Druker, ... Oncotarget 11 (29), 2807, 2020 | 6 | 2020 |
Exome sequencing informs mechanisms of clinical resistance to the FLT3-D835 inhibitor crenolanib H Zhang, KM Watanabe-Smith, D Bottomly, B Wilmot, SK McWeeney, ... Blood 126 (23), 2468, 2015 | 5 | 2015 |
Factors Predicting Response and Resistance to Midostaurin in FLT3 Positive and FLT3 Negative AML in 483 Primary AML Patient Samples K Watanabe-Smith, M Rosenberg, T Bucy, JW Tyner, U Borate Blood 130, 296, 2017 | 2 | 2017 |
Critical Role Of Interleukin Receptor Signaling In Acute Myeloid Leukemia Identified Using An RNAi Functional Screen A Agarwal, RJ Meckenzie, A Carey, M Davare, CA Eide, ... Blood 122 (21), 473, 2013 | 2 | 2013 |
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RGL4 over Expression Correlates with Variation in Midostaurin Response in FLT3-ITD Mutant AML Samples M Rosenberg, CE Tognon, KM Watanabe-Smith, U Borate Blood 132, 1365, 2018 | 1 | 2018 |
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