| A shear gradient–dependent platelet aggregation mechanism drives thrombus formation WS Nesbitt, E Westein, FJ Tovar-Lopez, E Tolouei, A Mitchell, J Fu, ... Nature medicine 15 (6), 665-673, 2009 | 939 | 2009 |
| PI 3-kinase p110β: a new target for antithrombotic therapy SP Jackson, SM Schoenwaelder, I Goncalves, WS Nesbitt, CL Yap, ... Nature medicine 11 (5), 507-514, 2005 | 725 | 2005 |
| Signaling events underlying thrombus formation SP Jackson, WS Nesbitt, S Kulkarni Journal of Thrombosis and Haemostasis 1 (7), 1602-1612, 2003 | 556 | 2003 |
| Dynamics of platelet thrombus formation SP Jackson, WS Nesbitt, E Westein Journal of thrombosis and Haemostasis 7, 17-20, 2009 | 287 | 2009 |
| Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation MJ Maxwell, E Westein, WS Nesbitt, S Giuliano, SM Dopheide, ... Blood 109 (2), 566-576, 2007 | 280 | 2007 |
| Distinct glycoprotein Ib/V/IX and integrin αIIbβ3-dependent calcium signals cooperatively regulate platelet adhesion under flow WS Nesbitt, S Kulkarni, S Giuliano, I Goncalves, SM Dopheide, CL Yap, ... Journal of Biological Chemistry 277 (4), 2965-2972, 2002 | 223 | 2002 |
| Intercellular calcium communication regulates platelet aggregation and thrombus growth WS Nesbitt, S Giuliano, S Kulkarni, SM Dopheide, IS Harper, SP Jackson The Journal of cell biology 160 (7), 1151-1161, 2003 | 217 | 2003 |
| The von Willebrand factor-glycoprotein Ib/V/IX interaction induces actin polymerization and cytoskeletal reorganization in rolling platelets and glycoprotein Ib/V/IX … Y Yuan, S Kulkarni, P Ulsemer, SL Cranmer, CL Yap, WS Nesbitt, I Harper, ... Journal of Biological Chemistry 274 (51), 36241-36251, 1999 | 160 | 1999 |
| A microfluidics device to monitor platelet aggregation dynamics in response to strain rate micro-gradients in flowing blood FJ Tovar-Lopez, G Rosengarten, E Westein, K Khoshmanesh, ... Lab on a Chip 10 (3), 291-302, 2010 | 155 | 2010 |
| Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth A Ono, E Westein, S Hsiao, WS Nesbitt, JR Hamilton, SM Schoenwaelder, ... Blood, The Journal of the American Society of Hematology 112 (1), 90-99, 2008 | 152 | 2008 |
| Synergistic adhesive interactions and signaling mechanisms operating between platelet glycoprotein Ib/IX and integrin αIIbβ3: studies in human platelets and transfected Chinese … CL Yap, SC Hughan, SL Cranmer, WS Nesbitt, MM Rooney, S Giuliano, ... Journal of Biological Chemistry 275 (52), 41377-41388, 2000 | 131 | 2000 |
| Inhibition of phosphoinositide 3-kinase β SP Jackson, AD Robertson, V Kenche, P Thompson, H Prabaharan, ... US Patent 7,598,377, 2009 | 87 | 2009 |
| The impact of blood rheology on the molecular and cellular events underlying arterial thrombosis WS Nesbitt, P Mangin, HH Salem, SP Jackson Journal of Molecular Medicine 84, 989-995, 2006 | 84 | 2006 |
| Phosphoinositide 3-kinase p110β regulates integrin αIIbβ3 avidity and the cellular transmission of contractile forces SM Schoenwaelder, A Ono, WS Nesbitt, J Lim, K Jarman, SP Jackson Journal of biological chemistry 285 (4), 2886-2896, 2010 | 80 | 2010 |
| Importance of temporal flow gradients and integrin αIIbβ3 mechanotransduction for shear activation of platelets I Goncalves, WS Nesbitt, Y Yuan, SP Jackson Journal of Biological Chemistry 280 (15), 15430-15437, 2005 | 65 | 2005 |
| Inhibition of protease‐activated receptor 4 impairs platelet procoagulant activity during thrombus formation in human blood SL French, JF Arthur, H Lee, WS Nesbitt, RK Andrews, EE Gardiner, ... Journal of Thrombosis and Haemostasis 14 (8), 1642-1654, 2016 | 60 | 2016 |
| A novel monoclonal antibody against the extracellular domain of GPIbβ modulates vWF mediated platelet adhesion C Perrault, S Moog, E Rubinstein, M Santer, MJ Baas, C de la Salle, ... Thrombosis and haemostasis 86 (11), 1238-1248, 2001 | 58 | 2001 |
| An investigation on platelet transport during thrombus formation at micro-scale stenosis FJ Tovar-Lopez, G Rosengarten, M Nasabi, V Sivan, K Khoshmanesh, ... PloS one 8 (10), e74123, 2013 | 45 | 2013 |
| Techniques to examine platelet adhesive interactions under flow S Kulkarni, WS Nesbitt, SM Dopheide, SC Hughan, IS Harper, ... Platelets and Megakaryocytes: Volume 1: Functional Assays, 165-186, 2004 | 42 | 2004 |
| Fabrication of complex PDMS microfluidic structures and embedded functional substrates by one-step injection moulding C Szydzik, B Niego, G Dalzell, M Knoerzer, F Ball, WS Nesbitt, RL Medcalf, ... RSC advances 6 (91), 87988-87994, 2016 | 36 | 2016 |
