| Role of endogenous GLP-1 and GIP in beta cell compensatory responses to insulin resistance and cellular stress S Vasu, RC Moffett, B Thorens, PR Flatt PloS one 9 (6), e101005, 2014 | 89 | 2014 |
| Incretin receptor null mice reveal key role of GLP-1 but not GIP in pancreatic beta cell adaptation to pregnancy RC Moffett, S Vasu, B Thorens, DJ Drucker, PR Flatt PloS one 9 (6), e96863, 2014 | 85 | 2014 |
| Islet distribution of Peptide YY and its regulatory role in primary mouse islets and immortalised rodent and human beta-cell function and survival D Khan, S Vasu, RC Moffett, N Irwin, PR Flatt Molecular and cellular endocrinology 436, 102-113, 2016 | 73 | 2016 |
| Metabolic and neuroprotective effects of dapagliflozin and liraglutide in diabetic mice P Millar, N Pathak, V Parthsarathy, AJ Bjourson, M O’Kane, V Pathak, ... Journal of Endocrinology 234 (3), 255-267, 2017 | 72 | 2017 |
| Beneficial effects of the novel cholecystokinin agonist (pGlu-Gln)-CCK-8 in mouse models of obesity/diabetes N Irwin, P Frizelle, IA Montgomery, RC Moffett, FPM O’harte, PR Flatt Diabetologia 55, 2747-2758, 2012 | 68 | 2012 |
| Influence of neuropeptide Y and pancreatic polypeptide on islet function and beta-cell survival D Khan, S Vasu, RC Moffett, N Irwin, PR Flatt Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (4), 749-758, 2017 | 48 | 2017 |
| Differential molecular and cellular responses of GLP-1 secreting L-cells and pancreatic alpha cells to glucotoxicity and lipotoxicity S Vasu, RC Moffett, NH McClenaghan, PR Flatt Experimental cell research 336 (1), 100-108, 2015 | 42 | 2015 |
| Oxytocin is present in islets and plays a role in beta-cell function and survival S Mohan, D Khan, RC Moffett, N Irwin, PR Flatt Peptides 100, 260-268, 2018 | 39 | 2018 |
| Liraglutide and sitagliptin counter beta-to alpha-cell transdifferentiation in diabetes N Tanday, PR Flatt, N Irwin, RC Moffett Journal of Endocrinology 245 (1), 53-64, 2020 | 34 | 2020 |
| Emerging role of GIP and related gut hormones in fertility and PCOS RC Moffett, V Naughton Peptides 125, 170233, 2020 | 34 | 2020 |
| Positive effects of GLP‐1 receptor activation with liraglutide on pancreatic islet morphology and metabolic control in C57BL/KsJ db/db mice with degenerative … RC Moffett, S Patterson, N Irwin, PR Flatt Diabetes/metabolism research and reviews 31 (3), 248-255, 2015 | 32 | 2015 |
| Chemical cholecystokinin receptor activation protects against obesity-diabetes in high fat fed mice and has sustainable beneficial effects in genetic ob/ob mice N Irwin, IA Montgomery, RC Moffett, PR Flatt Biochemical Pharmacology 85 (1), 81-91, 2013 | 32 | 2013 |
| Alterations of glucose-dependent insulinotropic polypeptide and expression of genes involved in mammary gland and adipose tissue lipid metabolism during pregnancy and lactation RC Moffett, N Irwin, JME Francis, PR Flatt PLoS One 8 (11), e78560, 2013 | 29 | 2013 |
| Vasopressin receptors in islets enhance glucose tolerance, pancreatic beta-cell secretory function, proliferation and survival S Mohan, RC Moffett, KG Thomas, N Irwin, PR Flatt Biochimie 158, 191-198, 2019 | 28 | 2019 |
| The altered enteroendocrine reportoire following roux-en-Y-gastric bypass as an effector of weight loss and improved glycaemic control RC Moffett, NG Docherty, CW le Roux Appetite 156, 104807, 2021 | 27 | 2021 |
| Beneficial metabolic actions of a stable GIP agonist following pre-treatment with a SGLT2 inhibitor in high fat fed diabetic mice PJB Millar, V Pathak, RC Moffett, NM Pathak, AJ Bjourson, MJ O'Kane, ... Molecular and Cellular Endocrinology 420, 37-45, 2016 | 26 | 2016 |
| Effects of glucose-dependent insulinotropic polypeptide receptor knockout and a high-fat diet on cognitive function and hippocampal gene expression in mice Erratum in/10.3892 … RR Lennox, C Moffett, DW Porter, N Irwin, VA Gault, PR Flatt Molecular medicine reports 12 (1), 1544-1548, 2015 | 26 | 2015 |
| Dapagliflozin exerts positive effects on beta cells, decreases glucagon and does not alter beta-to alpha-cell transdifferentiation in mouse models of diabetes and insulin … N Tanday, N Irwin, PR Flatt, RC Moffett Biochemical pharmacology 177, 114009, 2020 | 24 | 2020 |
| Effects of long-acting GIP, xenin and oxyntomodulin peptide analogues on alpha-cell transdifferentiation in insulin-deficient diabetic GluCreERT2; ROSA26-eYFP mice D Sarnobat, RC Moffett, VA Gault, N Tanday, F Reimann, FM Gribble, ... Peptides 125, 170205, 2020 | 24 | 2020 |
| Locally produced xenin and the neurotensinergic system in pancreatic islet function and β-cell survival D Khan, S Vasu, RC Moffett, VA Gault, PR Flatt, N Irwin Biological Chemistry 399 (1), 79-92, 2017 | 24 | 2017 |
Peter R FlattProfessor, University of UlsterVerified email at ulster.ac.uk
