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Jiafeng (Jeff) Geng, Ph.D.
Jiafeng (Jeff) Geng, Ph.D.
Sr. Director of Intellectual Property and Research Programs, Emory University
Verified email at emory.edu
Title
Cited by
Cited by
Year
Control of carotenoid biosynthesis through a heme-based cis-trans isomerase
J Beltrán, B Kloss, JP Hosler, J Geng, A Liu, A Modi, JH Dawson, M Sono, ...
Nature chemical biology 11 (8), 598-605, 2015
832015
Tryptophan-mediated charge-resonance stabilization in the bis-Fe (IV) redox state of MauG
J Geng, K Dornevil, VL Davidson, A Liu
Proceedings of the National Academy of Sciences 110 (24), 9639-9644, 2013
752013
Mutagenesis of tryptophan199 suggests that hopping is required for MauG-dependent tryptophan tryptophylquinone biosynthesis
NA Tarboush, LMR Jensen, ET Yukl, J Geng, A Liu, CM Wilmot, ...
Proceedings of the National Academy of Sciences 108 (41), 16956-16961, 2011
692011
Heme-dependent dioxygenases in tryptophan oxidation
J Geng, A Liu
Archives of biochemistry and biophysics 544, 18-26, 2014
602014
Enzyme reactivation by hydrogen peroxide in heme-based tryptophan dioxygenase
R Fu, R Gupta, J Geng, K Dornevil, S Wang, Y Zhang, MP Hendrich, A Liu
Journal of Biological Chemistry 286 (30), 26541-26554, 2011
522011
Chemical rescue of the distal histidine mutants of tryptophan 2, 3-dioxygenase
J Geng, K Dornevil, A Liu
Journal of the American Chemical Society 134 (29), 12209-12218, 2012
372012
Probing Bis‐FeIV MauG: Experimental Evidence for the Long‐Range Charge‐Resonance Model
J Geng, I Davis, A Liu
Angewandte Chemie 127 (12), 3763-3767, 2015
332015
Effects of the loss of the axial tyrosine ligand of the low-spin heme of MauG on its physical properties and reactivity
NA Tarboush, S Shin, J Geng, A Liu, VL Davidson
FEBS letters 586 (24), 4339-4343, 2012
232012
An iron reservoir to the catalytic metal: the rubredoxin iron in an extradiol dioxygenase
F Liu, J Geng, RH Gumpper, A Barman, I Davis, A Ozarowski, ...
Journal of Biological Chemistry 290 (25), 15621-15634, 2015
222015
Bis-Fe (IV): nature’s sniper for long-range oxidation
J Geng, I Davis, F Liu, A Liu
JBIC Journal of Biological Inorganic Chemistry 19, 1057-1067, 2014
222014
Photoirradiation generates an ultrastable 8-formyl FAD semiquinone radical with unusual properties in formate oxidase
JM Robbins, J Geng, BA Barry, G Gadda, AS Bommarius
Biochemistry 57 (40), 5818-5826, 2018
172018
Kinetic and spectroscopic characterization of the catalytic ternary complex of tryptophan 2, 3-dioxygenase
J Geng, AC Weitz, K Dornevil, MP Hendrich, A Liu
Biochemistry 59 (30), 2813-2822, 2020
92020
Heme binding to HupZ with a C-terminal tag from group A Streptococcus
ES Traore, J Li, T Chiura, J Geng, AJ Sachla, F Yoshimoto, Z Eichenbaum, ...
Molecules 26 (3), 549, 2021
82021
An Ultraviolet Resonance Raman Spectroscopic Study of Cisplatin and Transplatin Interactions with Genomic DNA
J Geng, M Aioub, MA El-Sayed, BA Barry
The Journal of Physical Chemistry B 121 (38), 8975-8983, 2017
72017
Heterolytic OO bond cleavage: Functional role of Glu113 during bis-Fe (IV) formation in MauG
J Geng, L Huo, A Liu
Journal of inorganic biochemistry 167, 60-67, 2017
52017
UV Resonance Raman Study of Apoptosis, Platinum‐Based Drugs, and Human Cell Lines
J Geng, M Aioub, MA El‐Sayed, BA Barry
ChemPhysChem 19 (12), 1428-1431, 2018
32018
Metalloenzymes involved in carotenoid biosynthesis in plants
I Davis, J Geng, A Liu
Methods in enzymology 671, 207-222, 2022
22022
Discovery of 5′-Substituted 5-Fluoro-2′-deoxyuridine Monophosphate Analogs: A Novel Class of Thymidylate Synthase Inhibitors
M Dasari, SC Pelly, J Geng, HB Gold, N Pribut, SK Sharma, MP D’Erasmo, ...
ACS Pharmacology & Translational Science 6 (5), 702-709, 2023
2023
Heme-dependent Tryptophan Oxidation: Mechanistic Studies on Tryptophan 2, 3-Dioxygenase and MauG
J Geng
2014
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Articles 1–19