| Hydrophobicity-shake flasks, protein folding and drug discovery A Sarkar, GE Kellogg Current topics in medicinal chemistry 10 (1), 67-83, 2010 | 153 | 2010 |
| DrugPred: a structure-based approach to predict protein druggability developed using an extensive nonredundant data set A Krasowski, D Muthas, A Sarkar, S Schmitt, R Brenk Journal of chemical information and modeling 51 (11), 2829-2842, 2011 | 98 | 2011 |
| Designing allosteric regulators of thrombin. Exosite 2 features multiple subsites that can be targeted by sulfated small molecules for inducing inhibition PS Sidhu, MH Abdel Aziz, A Sarkar, AY Mehta, Q Zhou, UR Desai Journal of medicinal chemistry 56 (12), 5059-5070, 2013 | 63 | 2013 |
| Allosteric Competitive Inhibitors of the Glucose-1-phosphate Thymidylyltransferase (RmlA) from Pseudomonas aeruginosa MS Alphey, L Pirrie, LS Torrie, WA Boulkeroua, M Gardiner, A Sarkar, ... ACS chemical biology 8 (2), 387-396, 2013 | 53 | 2013 |
| Structure–activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2, 4-dione: Development of potential substrate-specific ERK1/2 inhibitors Q Li, A Al-Ayoubi, T Guo, H Zheng, A Sarkar, T Nguyen, ST Eblen, S Grant, ... Bioorganic & medicinal chemistry letters 19 (21), 6042-6046, 2009 | 51 | 2009 |
| A simple method for discovering druggable, specific glycosaminoglycan-protein systems. Elucidation of key principles from heparin/heparan sulfate-binding proteins A Sarkar, UR Desai PloS one 10 (10), e0141127, 2015 | 50 | 2015 |
| Premature activation of the paramyxovirus fusion protein before target cell attachment with corruption of the viral fusion machinery SF Farzan, LM Palermo, CC Yokoyama, G Orefice, M Fornabaio, A Sarkar, ... Journal of Biological Chemistry 286 (44), 37945-37954, 2011 | 44 | 2011 |
| Allosteric inhibition of human factor XIa: discovery of monosulfated benzofurans as a class of promising inhibitors MD Argade, AY Mehta, A Sarkar, UR Desai Journal of medicinal chemistry 57 (8), 3559-3569, 2014 | 34 | 2014 |
| Estimating glycosaminoglycan–protein interaction affinity: water dominates the specific antithrombin–heparin interaction A Sarkar, W Yu, UR Desai, AD MacKerell, PD Mosier Glycobiology 26 (10), 1041-1047, 2016 | 21 | 2016 |
| Designing “high-affinity, high-specificity” glycosaminoglycan sequences through computerized modeling NV Sankaranarayanan, A Sarkar, UR Desai, PD Mosier Glycosaminoglycans: Chemistry and Biology, 289-314, 2015 | 20 | 2015 |
| Chemoenzymatically prepared heparan sulfate containing rare 2-O-sulfonated glucuronic acid residues RS Boothello, A Sarkar, VM Tran, TKN Nguyen, NV Sankaranarayanan, ... ACS Chemical Biology 10 (6), 1485-1494, 2015 | 16 | 2015 |
| Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics A Sarkar, KC Anderson, GE Kellogg European journal of medicinal chemistry 52, 98-110, 2012 | 13 | 2012 |
| To Hit or Not to Hit, That Is the Question – Genome-wide Structure-Based Druggability Predictions for Pseudomonas aeruginosa Proteins A Sarkar, R Brenk PLoS One 10 (9), e0137279, 2015 | 12 | 2015 |
| Challenges in drug discovery for intracellular bacteria AN Tucker, TJ Carlson, A Sarkar Pathogens 10 (9), 1172, 2021 | 9 | 2021 |
| Resisting resistance: gearing up for war A Sarkar, S Garneau-Tsodikova MedChemComm 10 (9), 1512-1516, 2019 | 6 | 2019 |
| Docking, Scoring, and Virtual Screening in Drug Discovery F Spyrakis, A Sarkar, GE Kellogg Burger's Medicinal Chemistry and Drug Discovery, 1-102, 2003 | 4 | 2003 |
| β-Lactamase Suppression as a Strategy to Target Methicillin-Resistant Staphylococcus aureus: Proof of Concept PM Thomas, MA Deming, A Sarkar ACS omega 7 (50), 46213-46221, 2022 | 2 | 2022 |
| Enabling design of screening libraries for antibiotic discovery by modeling ChEMBL data A Sarkar European Journal of Pharmaceutical Sciences 143, 105166, 2020 | 2 | 2020 |
| Editorial [Hot topic: Applying Induced Fit in Drug Discovery: Square Pegs and Round Holes?(Guest Editors: Francesca Spyrakis, Pietro Cozzini, Aurijit Sarkar and Glen E. Kellogg)] F Spyrakis, P Cozzini, A Sarkar, G E Kellogg Current Topics in Medicinal Chemistry 11 (2), 131-132, 2011 | 2 | 2011 |
| A beginner’s guide to measuring binding affinity during biomolecular interactions HI Martin, V Agnihotri, RM Yennamalli, A Sarkar Basic Biotechniques for Bioprocess and Bioentrepreneurship, 259-270, 2023 | 1 | 2023 |
Umesh DesaiProfessor of Medicinal Chemistry, Virginia Commonwealth UniversityVerified email at vcu.edu
