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Tobias John
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SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ...
Cell stem cell 29 (2), 217-231. e8, 2022
1732022
Allosteric inhibition of the SARS‐CoV‐2 Main protease: insights from mass spectrometry based assays
TJ El‐Baba, CA Lutomski, AL Kantsadi, TR Malla, T John, V Mikhailov, ...
Angewandte Chemie International Edition 59 (52), 23544-23548, 2020
992020
Discovery of SARS-CoV-2 M pro peptide inhibitors from modelling substrate and ligand binding
HTH Chan, MA Moesser, RK Walters, TR Malla, RM Twidale, T John, ...
Chemical science 12 (41), 13686-13703, 2021
632021
COVID moonshot: open science discovery of SARS-CoV-2 main protease inhibitors by combining crowdsourcing, high-throughput experiments, computational simulations, and machine …
H Achdout, A Aimon, E Bar-David, GM Morris
BioRxiv, 2020
532020
Mass spectrometry reveals potential of β-lactams as SARS-CoV-2 M pro inhibitors
TR Malla, A Tumber, T John, L Brewitz, C Strain-Damerell, CD Owen, ...
Chemical Communications 57 (12), 1430-1433, 2021
452021
Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors
COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ...
BioRxiv, 2020.10. 29.339317, 2020
362020
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors
ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ...
Science 382 (6671), eabo7201, 2023
252023
Roles of metal ions in the selective inhibition of oncogenic variants of isocitrate dehydrogenase 1
S Liu, MI Abboud, T John, V Mikhailov, I Hvinden, J Walsby-Tickle, X Liu, ...
Communications Biology 4 (1), 1243, 2021
182021
V Robinson C
TJ El-Baba, CA Lutomski, AL Kantsadi, TR Malla, T John, V Mikhailov, ...
Allosteric inhibition of the SARS-CoV-2 main protease: insights from mass …, 2020
62020
Formaldehyde quantification using ampicillin is not selective
R Reinbold, T John, P Spingardi, A Kawamura, AL Thompson, ...
Scientific Reports 9 (1), 18289, 2019
62019
Formaldehyde reacts with N-terminal proline residues to give bicyclic aminals
T John, E Pires, SS Hester, E Salah, RJ Hopkinson, CJ Schofield
Communications Chemistry 6 (1), 12, 2023
22023
Conceptual design of UAV using modular approach
AS Kumar, LG Hardik, DK Kumar, B Ramya, T John
AIP Conference Proceedings 2317 (1), 2021
22021
Metampicillin is a cyclic aminal produced by reaction of ampicillin with formaldehyde
R Reinbold, T John, P Spingardi, A Kawamura, CJ Schofield, ...
Scientific Reports 10 (1), 17955, 2020
22020
Aldehyde-mediated inhibition of asparagine biosynthesis has implications for diabetes and alcoholism
T John, N Saffoon, J Walsby-Tickle, SS Hester, FA Dingler, CL Millington, ...
Chemical Science 15 (7), 2509-2517, 2024
2024
Egg-derived anti-SARS-CoV-2 immunoglobulin Y (IgY) with broad variant activity as intranasal prophylaxis against COVID-19 (preprint)
LR Frumkin, M Lucas, CL Scribner, N Ortega-Heinly, J Rogers, G Yin, ...
2022
Discovery of SARS-CoV-2 Mpro Peptide Inhibitors from Modelling Substrate and Ligand Binding (preprint)
HTH Chan, MA Moesser, RK Walters, TR Malla, RM Twidale, T John, ...
2021
Studies on the reactions of formaldehyde with protein N-termini and related biomolecules
T John
University of Oxford, 2021
2021
Allosteric inhibition of the SARS-CoV-2 main protease-insights from mass spectrometry-based assays (preprint)
TJ El-Baba, CA Lutomski, AL Kantsadi, TR Malla, T John, V Mikhailov, ...
2020
Evidence for adaptive evolution in the receptor-binding domain of seasonal coronaviruses (preprint)
K Kistler, T Bedford, A Undale, K Arora, NM Arora, BPD Purkayastha, ...
2020
A cell-free antibody engineering platform rapidly generates SARS-CoV-2 neutralizing antibodies (preprint)
X Chen, M Gentili, N Hacohen, A Regev, H Barr, A Ben-Shmuel, J Bennett, ...
2020
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