The oxysterol receptor LXR inhibits proliferation of human breast cancer cells LL Vedin, SA Lewandowski, P Parini, JÅ Gustafsson, KR Steffensen Carcinogenesis 30 (4), 575-579, 2009 | 220 | 2009 |
Liver× receptor ligands disrupt breast cancer cell proliferation through an E2F-mediated mechanism T Nguyen-Vu, LL Vedin, K Liu, P Jonsson, JZ Lin, NR Candelaria, ... Breast cancer research 15, 1-12, 2013 | 99 | 2013 |
The oxysterol receptors LXRα and LXRβ suppress proliferation in the colon LL Vedin, JÅ Gustafsson, KR Steffensen Molecular carcinogenesis 52 (11), 835-844, 2013 | 86 | 2013 |
Estrogen receptor ligands ameliorate fatty liver through a nonclassical estrogen receptor/Liver X receptor pathway in mice S Han, Y Komatsu, A Murayama, KR Steffensen, Y Nakagawa, ... Hepatology 59 (5), 1791-1802, 2014 | 77 | 2014 |
Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells NR Candelaria, S Addanki, J Zheng, T Nguyen-Vu, H Karaboga, P Dey, ... PloS one 9 (9), e106289, 2014 | 63 | 2014 |
The oxysterol receptor LXRβ protects against DSS-and TNBS-induced colitis in mice T Jakobsson, LL Vedin, T Hassan, N Venteclef, D Greco, M D'amato, ... Mucosal immunology 7 (6), 1416-1428, 2014 | 54 | 2014 |
Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα N Liang, A Damdimopoulos, S Goñi, Z Huang, LL Vedin, T Jakobsson, ... Nature communications 10 (1), 1684, 2019 | 47 | 2019 |
The emerging roles of liver X receptors and their ligands in cancer CY Lin, LL Vedin, KR Steffensen Expert opinion on therapeutic targets 20 (1), 61-71, 2016 | 43 | 2016 |
The lipid droplet-associated protein perilipin 3 facilitates hepatitis C virus-driven hepatic steatosis D Ferguson, J Zhang, MA Davis, RN Helsley, LL Vedin, RG Lee, ... Journal of lipid research 58 (2), 420-432, 2017 | 36 | 2017 |
Potential role of thyroid receptor β agonists in the treatment of hyperlipidemia T Jakobsson, LL Vedin, P Parini Drugs 77, 1613-1621, 2017 | 33 | 2017 |
Knockdown of SF-1 and RNF31 affects components of steroidogenesis, TGFβ, and Wnt/β-catenin signaling in adrenocortical carcinoma cells A Ehrlund, P Jonsson, LL Vedin, C Williams, JÅ Gustafsson, E Treuter PloS one 7 (3), e32080, 2012 | 32 | 2012 |
Insights from liver‐humanized mice on cholesterol lipoprotein metabolism and LXR‐agonist pharmacodynamics in humans ME Minniti, M Pedrelli, LL Vedin, AS Delbès, RGP Denis, K Öörni, C Sala, ... Hepatology 72 (2), 656-670, 2020 | 29 | 2020 |
Soat2 ties cholesterol metabolism to β‐oxidation and glucose tolerance in male mice C Pramfalk, O Ahmed, M Pedrelli, ME Minniti, S Luquet, RGP Denis, ... Journal of Internal Medicine 292 (2), 296-307, 2022 | 7 | 2022 |
Liver-humanized mice exhibit lipoprotein-specific phenotypes when grafted with human hepatocytes from different donors ME Minniti, LL Vedin, EM Wilson, KR Steffensen, P Parini Atherosclerosis 263, e7, 2017 | 3 | 2017 |
Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior AS Delbès, M Quiñones, C Gobet, J Castel, RGP Denis, J Berthelet, ... Science Advances 9 (20), eadf2982, 2023 | 2 | 2023 |
Liver X receptor agonist blocks pancreatic cancer cell proliferation. NR Candelaria, S Manchem, HT Vu, J Zheng, C Gabbi, P Dey, ... Cancer Research 73 (8_Supplement), 1310-1310, 2013 | 2 | 2013 |
Liver X receptors induce antiproliferative effects in basal‐like breast cancer MH Haugen, H von der Lippe Gythfeldt, EV Egeland, L Svartdal Normann, ... Molecular Oncology 17 (10), 2041-2055, 2023 | 1 | 2023 |
Metabolic characterization of the high-fat/high sucrose diet challenge in liver-humanized mice ME Minniti, M Pedrelli, LL Vedin, AS Delbès, RGP Denis, P Garagnani, ... Atherosclerosis 315, e99-e100, 2020 | | 2020 |
Reduction of bile acid synthesis and intrahepatic lipid accumulation in liver-humanized mice define the unfavorable pharmacodynamics of LXR agonism in humans ME Minniti, LL Vedin, M Pedrelli, K Öörni, SH Luquet, EM Wilson, J Bial, ... Atherosclerosis 287, e28-e29, 2019 | | 2019 |
Genetic depletion of the Soat2 gene diminishes diet-induced hepatic steatosis and improves glucose tolerance in mice C Pramfalk, O Ahmed, L Larsson, J Härdfeldt, M Pedrelli, L Vedin, ... Atherosclerosis 275, e25, 2018 | | 2018 |