| The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a … JS Bae, L Yang, C Manithody, AR Rezaie Blood, The Journal of the American Society of Hematology 110 (12), 3909-3916, 2007 | 234 | 2007 |
| Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells JS Bae, L Yang, AR Rezaie Proceedings of the National Academy of Sciences 104 (8), 2867-2872, 2007 | 221 | 2007 |
| Polyphosphate amplifies proinflammatory responses of nuclear proteins through interaction with receptor for advanced glycation end products and P2Y1 purinergic … P Dinarvand, SM Hassanian, SH Qureshi, C Manithody, JC Eissenberg, ... Blood, The Journal of the American Society of Hematology 123 (6), 935-945, 2014 | 127 | 2014 |
| Engineering a disulfide bond to stabilize the calcium-binding loop of activated protein C eliminates its anticoagulant but not its protective signaling properties JS Bae, L Yang, C Manithody, AR Rezaie Journal of biological chemistry 282 (12), 9251-9259, 2007 | 121 | 2007 |
| Activated protein C protects against myocardial ischemic/reperfusion injury through AMP‐activated protein kinase signaling J Wang, L Yang, AR Rezaie, J Li Journal of Thrombosis and Haemostasis 9 (7), 1308-1317, 2011 | 109 | 2011 |
| Lipid raft localization regulates the cleavage specificity of protease activated receptor 1 in endothelial cells JS Bae, L Yang, AR Rezaie Journal of Thrombosis and Haemostasis 6 (6), 954-961, 2008 | 86 | 2008 |
| Localization of the heparin binding exosite of factor IXa L Yang, C Manithody, AR Rezaie Journal of Biological Chemistry 277 (52), 50756-50760, 2002 | 78 | 2002 |
| Occupancy of human EPCR by protein C induces β-arrestin-2 biased PAR1 signaling by both APC and thrombin RV Roy, A Ardeshirylajimi, P Dinarvand, L Yang, AR Rezaie Blood, The Journal of the American Society of Hematology 128 (14), 1884-1893, 2016 | 74 | 2016 |
| Identification of a specific exosite on activated protein C for interaction with protease-activated receptor 1 L Yang, JS Bae, C Manithody, AR Rezaie Journal of Biological Chemistry 282 (35), 25493-25500, 2007 | 68 | 2007 |
| Role of basic residues of the autolysis loop in the catalytic function of factor Xa C Manithody, L Yang, AR Rezaie Biochemistry 41 (21), 6780-6788, 2002 | 67 | 2002 |
| Proexosite-1 on prothrombin is a factor Va-dependent recognition site for the prothrombinase complex L Chen, L Yang, AR Rezaie Journal of Biological Chemistry 278 (30), 27564-27569, 2003 | 63 | 2003 |
| Contribution of basic residues of the 70− 80-loop to heparin binding and anticoagulant function of activated protein C L Yang, C Manithody, AR Rezaie Biochemistry 41 (19), 6149-6157, 2002 | 58 | 2002 |
| Antithrombin up-regulates AMP-activated protein kinase signalling during myocardial ischaemia/reperfusion injury Y Ma, J Wang, J Gao, H Yang, Y Wang, C Manithody, J Li, AR Rezaie Thrombosis and haemostasis 114 (02), 338-349, 2015 | 56 | 2015 |
| Factor X/Xa elicits protective signaling responses in endothelial cells directly via PAR-2 and indirectly via endothelial protein C receptor-dependent recruitment of PAR-1 JS Bae, L Yang, AR Rezaie Journal of biological chemistry 285 (45), 34803-34812, 2010 | 54 | 2010 |
| DX-9065a inhibition of factor Xa and the prothrombinase complex: mechanism of inhibition and comparison with therapeutic heparins AR Rezaie Thrombosis and Haemostasis 89 (01), 112-121, 2003 | 54 | 2003 |
| Thrombomodulin allosterically modulates the activity of the anticoagulant thrombin AR Rezaie, L Yang Proceedings of the National Academy of Sciences 100 (21), 12051-12056, 2003 | 53 | 2003 |
| Activation of protein C by the thrombin–thrombomodulin complex: Cooperative roles of Arg-35 of thrombin and Arg-67 of protein C L Yang, C Manithody, AR Rezaie Proceedings of the National Academy of Sciences 103 (4), 879-884, 2006 | 52 | 2006 |
| Characterization of a heparin-binding site on the catalytic domain of factor XIa: mechanism of heparin acceleration of factor XIa inhibition by the serpins antithrombin and C1 … L Yang, M Sun, D Gailani, AR Rezaie Biochemistry 48 (7), 1517-1524, 2009 | 51 | 2009 |
| Protein Z-dependent protease inhibitor binds to the C-terminal domain of protein Z AR Rezaie, JS Bae, C Manithody, SH Qureshi, L Yang Journal of biological chemistry 283 (29), 19922-19926, 2008 | 44 | 2008 |
| The fourth epidermal growth factor-like domain of thrombomodulin interacts with the basic exosite of protein C L Yang, AR Rezaie Journal of Biological Chemistry 278 (12), 10484-10490, 2003 | 42 | 2003 |
