| Carboxylated branched poly (β-amino ester) nanoparticles enable robust cytosolic protein delivery and CRISPR-Cas9 gene editing Y Rui, DR Wilson, J Choi, M Varanasi, K Sanders, J Karlsson, M Lim, ... Science advances 5 (12), eaay3255, 2019 | 140 | 2019 |
| Bioreducible Polymeric Nanoparticles Containing Multiplexed Cancer Stem Cell Regulating miRNAs Inhibit Glioblastoma Growth and Prolong Survival H Lopez-Bertoni, KL Kozielski, Y Rui, B Lal, H Vaughan, DR Wilson, ... Nano letters 18 (7), 4086-4094, 2018 | 126 | 2018 |
| Non-viral delivery to enable genome editing Y Rui, DR Wilson, JJ Green Trends in biotechnology 37 (3), 281-293, 2019 | 110 | 2019 |
| Cancer-selective nanoparticles for combinatorial siRNA delivery to primary human GBM in vitro and in vivo KL Kozielski, A Ruiz-Valls, SY Tzeng, H Guerrero-Cázares, Y Rui, Y Li, ... Biomaterials 209, 79-87, 2019 | 78 | 2019 |
| High-throughput and high-content bioassay enables tuning of polyester nanoparticles for cellular uptake, endosomal escape, and systemic in vivo delivery of mRNA Y Rui, DR Wilson, SY Tzeng, HM Yamagata, D Sudhakar, M Conge, ... Science Advances 8 (1), eabk2855, 2022 | 61 | 2022 |
| Reducible Branched Ester-Amine Quadpolymers (rBEAQs) Codelivering Plasmid DNA and RNA Oligonucleotides Enable CRISPR/Cas9 Genome Editing Y Rui, DR Wilson, K Sanders, JJ Green ACS applied materials & interfaces 11 (11), 10472-10480, 2019 | 51 | 2019 |
| Engineered nanoparticles for systemic siRNA delivery to malignant brain tumours J Karlsson, Y Rui, KL Kozielski, AL Placone, O Choi, SY Tzeng, J Kim, ... Nanoscale 11 (42), 20045-20057, 2019 | 50 | 2019 |
| Sox2 induces glioblastoma cell stemness and tumor propagation by repressing TET2 and deregulating 5hmC and 5mC DNA modifications H Lopez-Bertoni, A Johnson, Y Rui, B Lal, S Sall, M Malloy, JB Coulter, ... Signal transduction and targeted therapy 7 (1), 37, 2022 | 49 | 2022 |
| Nonviral polymeric nanoparticles for gene therapy in pediatric CNS malignancies J Choi, Y Rui, J Kim, N Gorelick, DR Wilson, K Kozielski, A Mangraviti, ... Nanomedicine: Nanotechnology, Biology and Medicine 23, 102115, 2020 | 47 | 2020 |
| A Sox2: miR-486-5p Axis Regulates Survival of GBM Cells by Inhibiting Tumor Suppressor Networks H Lopez-Bertoni, IS Kotchetkov, N Mihelson, B Lal, Y Rui, H Ames, ... Cancer Research 80 (8), 1644-1655, 2020 | 45 | 2020 |
| Non-viral nucleic acid containing nanoparticles as cancer therapeutics KL Kozielski, Y Rui, JJ Green Expert opinion on drug delivery 13 (10), 1475-1487, 2016 | 43 | 2016 |
| HIF-1α and HIF-2α redundantly promote retinal neovascularization in patients with ischemic retinal disease J Zhang, Y Qin, M Martinez, M Flores-Bellver, M Rodrigues, ... The Journal of Clinical Investigation 131 (12), 2021 | 41 | 2021 |
| Poly (Beta-Amino Ester) Nanoparticles Enable Nonviral Delivery of CRISPR-Cas9 Plasmids for Gene Knockout and Gene Deletion Y Rui, M Varanasi, S Mendes, HM Yamagata, DR Wilson, JJ Green Molecular Therapy-Nucleic Acids 20, 661-672, 2020 | 41 | 2020 |
| Photocrosslinked Bioreducible Polymeric Nanoparticles for Enhanced Systemic siRNA Delivery as Cancer Therapy J Karlsson, SY Tzeng, S Hemmati, KM Luly, O Choi, Y Rui, DR Wilson, ... Advanced Functional Materials 31 (17), 2009768, 2021 | 32 | 2021 |
| Poly (ethylene glycol)–Poly (beta-amino ester)-Based Nanoparticles for Suicide Gene Therapy Enhance Brain Penetration and Extend Survival in a Preclinical Human Glioblastoma … J Kim, SK Mondal, SY Tzeng, Y Rui, R Al-Kharboosh, KK Kozielski, ... ACS Biomaterials Science & Engineering 6 (5), 2943-2955, 2020 | 32 | 2020 |
| Differentially Branched Ester Amine Quadpolymers with Amphiphilic and pH-Sensitive Properties for Efficient Plasmid DNA Delivery DR Wilson, Y Rui, K Siddiq, D Routkevitch, JJ Green Molecular pharmaceutics 16 (2), 655-668, 2019 | 29 | 2019 |
| Genome‐wide investigation of intragenic DNA methylation identifies ZMIZ1 gene as a prognostic marker in glioblastoma and multiple cancer types D Mathios, T Hwang, Y Xia, J Phallen, Y Rui, AP See, R Maxwell, ... International journal of cancer 145 (12), 3425-3435, 2019 | 21 | 2019 |
| A Triple-Fluorophore-Labeled Nucleic Acid pH Nanosensor to Investigate Non-viral Gene Delivery DR Wilson, D Routkevitch, Y Rui, A Mosenia, KJ Wahlin, ... Molecular Therapy 25 (7), 1697-1709, 2017 | 20 | 2017 |
| PAI-1 is a vascular cell–specific HIF-2–dependent angiogenic factor that promotes retinal neovascularization in diabetic patients Y Qin, J Zhang, S Babapoor-Farrokhran, B Applewhite, M Deshpande, ... Science Advances 8 (9), eabm1896, 2022 | 16 | 2022 |
| Overcoming delivery barriers in immunotherapy for glioblastoma Y Rui, JJ Green Drug Delivery and Translational Research 11 (6), 2302-2316, 2021 | 15 | 2021 |
Jordan J. GreenProfessor of BME, ChemBE, MSE, Ophthalmology, Oncology, Neurosurgery at Johns Hopkins UniversityVerified email at jhu.edu
