Joshua Dempster

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Francisca VazquezDirector, Cancer Dependency Map, Broad InstituteAdresse e-mail validée de broadinstitute.org
David E. RootBroad InstituteAdresse e-mail validée de broadinstitute.org
Aviad TsherniakBroad Institute of Harvard and MITAdresse e-mail validée de broadinstitute.org
James M McFarlandBroad InstituteAdresse e-mail validée de broadinstitute.org
Jesse BoehmInstitute Scientist, Cancer Program, Broad InstituteAdresse e-mail validée de broadinstitute.org
John Michael Krill-BurgerSenior Scientist, MerckAdresse e-mail validée de merck.com
Todd GolubBroad InstituteAdresse e-mail validée de broadinstitute.org
Monica Olvera de la CruzLawyer Taylor Professor of Materials Science and Engineering, Northwestern UniversityAdresse e-mail validée de northwestern.edu
Mariya KazachkovaUC San DiegoAdresse e-mail validée de health.ucsd.edu
Jordan BryanUniversity of North Carolina at Chapel HillAdresse e-mail validée de unc.edu
John G. DoenchBroad InstituteAdresse e-mail validée de broadinstitute.org
Emanuel GonçalvesINESC-ID & IST - Universidade de LisboaAdresse e-mail validée de tecnico.ulisboa.pt
Francesco IorioHuman TechnopoleAdresse e-mail validée de fht.org
Mathew GarnettWellcome Sanger InstituteAdresse e-mail validée de sanger.ac.uk
Hanna NajgebauerWellcome Sanger InstituteAdresse e-mail validée de sanger.ac.uk
Zandra V HoTrinity Health Ann Arbor HospitalAdresse e-mail validée de alumni.stanford.edu
Jordan RossenDepartment of Epidemiology, Harvard T.H. Chan School of Public HealthAdresse e-mail validée de g.harvard.edu
Scott YoungerChildren's Mercy HospitalAdresse e-mail validée de cmh.edu
Brenton R PaolellaBroad Institute of MIT and HarvardAdresse e-mail validée de broadinstitute.org
Joshua PanGoogle DeepMindAdresse e-mail validée de deepmind.com

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Joshua Dempster

Group Lead in Computational Science, Broad Institute

Adresse e-mail validée de broadinstitute.org

data science bioinformatics cancer biology machine learning


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Genetic and transcriptional evolution alters cancer cell line drug response U Ben-David, B Siranosian, G Ha, H Tang, Y Oren, K Hinohara, ... Nature 560 (7718), 325-330, 2018	806	2018
Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration JM McFarland, ZV Ho, G Kugener, JM Dempster, PG Montgomery, ... Nature Communications 9 (1), 2018	328	2018
Extracting biological insights from the project achilles genome-scale CRISPR screens in cancer cell lines JM Dempster, J Rossen, M Kazachkova, J Pan, G Kugener, DE Root, ... BioRxiv, 720243, 2019	290	2019
Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets JM Dempster, C Pacini, S Pantel, FM Behan, T Green, J Krill-Burger, ... Nature communications 10 (1), 5817, 2019	180	2019
Integrated cross-study datasets of genetic dependencies in cancer C Pacini, JM Dempster, I Boyle, E Gonçalves, H Najgebauer, E Karakoc, ... Nature communications 12 (1), 1661, 2021	178	2021
Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects JM Dempster, I Boyle, F Vazquez, DE Root, JS Boehm, WC Hahn, ... Genome biology 22, 1-23, 2021	159	2021
Noncanonical open reading frames encode functional proteins essential for cancer cell survival JR Prensner, OM Enache, V Luria, K Krug, KR Clauser, JM Dempster, ... Nature biotechnology 39 (6), 697-704, 2021	97	2021
Targetable vulnerabilities in T-and NK-cell lymphomas identified through preclinical models SY Ng, N Yoshida, AL Christie, M Ghandi, NV Dharia, J Dempster, ... Nature communications 9 (1), 2024, 2018	93	2018
A first-generation pediatric cancer dependency map NV Dharia, G Kugener, LM Guenther, CF Malone, AD Durbin, AL Hong, ... Nature genetics 53 (4), 529-538, 2021	87	2021
Synthetic lethal interaction of SHOC2 depletion with MEK inhibition in RAS-driven cancers R Sulahian, JJ Kwon, KH Walsh, E Pailler, TL Bosse, M Thaker, ... Cell reports 29 (1), 118-134. e8, 2019	71	2019
Understanding degenerate ground states of a protected quantum circuit in the presence of disorder JM Dempster, B Fu, DG Ferguson, DI Schuster, J Koch Physical Review B 90 (9), 094518, 2014	66	2014
Aggregation of heterogeneously charged colloids JM Dempster, M Olvera de la Cruz Acs Nano 10 (6), 5909-5915, 2016	47	2016
Phosphate dysregulation via the XPR1–KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer DP Bondeson, BR Paolella, A Asfaw, MV Rothberg, TA Skipper, ... Nature cancer 3 (6), 681-695, 2022	26	2022
Paramagnetic filaments in a fast precessing field: Planar versus helical conformations P Vázquez-Montejo, JM Dempster, MO de la Cruz Physical Review Materials 1 (6), 064402, 2017	26	2017
Contractile actuation and dynamical gel assembly of paramagnetic filaments in fast precessing fields JM Dempster, P Vázquez-Montejo, MO De La Cruz Physical Review E 95 (5), 052606, 2017	25	2017
Selective modulation of a pan-essential protein as a therapeutic strategy in cancer CF Malone, NV Dharia, G Kugener, AB Forman, MV Rothberg, ... Cancer discovery 11 (9), 2282-2299, 2021	24	2021
Gene expression has more power for predicting in vitro cancer cell vulnerabilities than genomics JM Dempster, JM Krill-Burger, JM McFarland, A Warren, JS Boehm, ... BioRxiv, 2020.02. 21.959627, 2020	24	2020
BAF complex maintains glioma stem cells in pediatric H3K27M glioma E Panditharatna, JG Marques, T Wang, MC Trissal, I Liu, L Jiang, A Beck, ... Cancer discovery 12 (12), 2880-2905, 2022	23	2022
Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration. Nat Commun. 2018; 9 (1): 4610 JM McFarland, ZV Ho, G Kugener, JM Dempster, PG Montgomery, ... Epub 2018/11/06. https://doi. org/10.1038/s41467-018-06916-5 PubMed Central …, 0	19
Comparative optimization of combinatorial CRISPR screens R Li, O Klingbeil, D Monducci, MJ Young, DJ Rodriguez, Z Bayyat, ... Nature Communications 13 (1), 2469, 2022	18	2022

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