HIV-1 Nef interferes with host cell motility by deregulation of Cofilin B Stolp, M Reichman-Fried, L Abraham, X Pan, SI Giese, S Hannemann, ... Cell host & microbe 6 (2), 174-186, 2009 | 139 | 2009 |
HIV-1 Nef: a multifaceted modulator of T cell receptor signaling L Abraham, OT Fackler Cell communication and signaling 10, 1-11, 2012 | 105 | 2012 |
Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor SA Freeman, V Jaumouillé, K Choi, BE Hsu, HS Wong, L Abraham, ... Nature communications 6 (1), 6168, 2015 | 104 | 2015 |
HIV-1 Nef compensates for disorganization of the immunological synapse by inducing trans-Golgi network–associated Lck signaling X Pan, JM Rudolph, L Abraham, A Habermann, C Haller, J Krijnse-Locker, ... Blood, The Journal of the American Society of Hematology 119 (3), 786-797, 2012 | 66 | 2012 |
TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma D Ennishi, S Healy, A Bashashati, S Saberi, C Hother, A Mottok, FC Chan, ... Nature medicine 26 (4), 577-588, 2020 | 65 | 2020 |
Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation M Bolger-Munro, K Choi, JM Scurll, L Abraham, RS Chappell, D Sheen, ... Elife 8, e44574, 2019 | 63 | 2019 |
Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling B Stolp, L Abraham, JM Rudolph, OT Fackler Journal of virology 84 (8), 3935-3948, 2010 | 62 | 2010 |
Phase separation and clustering of an ABC transporter in Mycobacterium tuberculosis F Heinkel, L Abraham, M Ko, J Chao, H Bach, LT Hui, H Li, M Zhu, ... Proceedings of the National Academy of Sciences 116 (33), 16326-16331, 2019 | 61 | 2019 |
Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells HM Baldauf, L Stegmann, SM Schwarz, I Ambiel, M Trotard, M Martin, ... Proceedings of the National Academy of Sciences 114 (10), 2729-2734, 2017 | 53 | 2017 |
Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA MT Kalathottukaren, L Abraham, PR Kapopara, BFL Lai, RA Shenoi, ... Blood, The Journal of the American Society of Hematology 129 (10), 1368-1379, 2017 | 40 | 2017 |
Limitations of Qdot labelling compared to directly-conjugated probes for single particle tracking of B cell receptor mobility L Abraham, HY Lu, RC Falcão, J Scurll, T Jou, B Irwin, R Tafteh, MR Gold, ... Scientific reports 7 (1), 11379, 2017 | 38 | 2017 |
HIV-1 Nef Limits Communication between Linker of Activated T Cells and SLP-76 To Reduce Formation of SLP-76–Signaling Microclusters following TCR Stimulation L Abraham, P Bankhead, X Pan, U Engel, OT Fackler The Journal of Immunology 189 (4), 1898-1910, 2012 | 34 | 2012 |
An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity NE Weisser, M Sanches, E Escobar-Cabrera, J O’Toole, E Whalen, ... Nature Communications 14 (1), 1394, 2023 | 28 | 2023 |
Association with PAK2 enables functional interactions of lentiviral Nef proteins with the exocyst complex A Imle, L Abraham, N Tsopoulidis, B Hoflack, K Saksela, OT Fackler MBio 6 (5), 10.1128/mbio. 01309-15, 2015 | 25 | 2015 |
Real-time 3D stabilization of a super-resolution microscope using an electrically tunable lens R Tafteh, L Abraham, D Seo, HY Lu, MR Gold, KC Chou Optics Express 24 (20), 22959-22970, 2016 | 18 | 2016 |
Targeted cell-to-cell delivery of protein payloads via the granzyme-perforin pathway DJ Woodsworth, L Dreolini, L Abraham, RA Holt Molecular Therapy Methods & Clinical Development 7, 132-145, 2017 | 16 | 2017 |
The bispecific antibody zanidatamab's (ZW25's) unique mechanisms of action and durable anti-tumor activity in HER2-expressing cancers NE Weisser, G Wickman, L Abraham, J O'Toole, B Harbourne, J Guedia, ... Cancer Research 81 (13_Supplement), 1005-1005, 2021 | 15 | 2021 |
Structure, function, and spatial organization of the B cell receptor L Abraham, JC Wang, M Bolger-Munro, MR Gold Academic Press, 2016 | 11 | 2016 |
MALT1-Dependent cleavage of HOIL1 modulates canonical NF-κB signaling and inflammatory responsiveness SY Fung, HY Lu, M Sharma, AA Sharma, A Saferali, A Jia, L Abraham, ... Frontiers in Immunology 12, 749794, 2021 | 7 | 2021 |
Tinospora cordifolia (Giloy) and autoimmune-like liver injury–a classic case of Primum Non Nocere,“first, do no harm” CA Philips, L Abraham, M for Ethics Journal of Clinical and Experimental Hepatology 12 (1), 245, 2022 | 6 | 2022 |