| Proteomic discovery of cellular substrates of the ClpXP protease reveals five classes of ClpX-recognition signals JM Flynn, SB Neher, YI Kim, RT Sauer, TA Baker Molecular cell 11 (3), 671-683, 2003 | 718 | 2003 |
| Sculpting the proteome with AAA+ proteases and disassembly machines RT Sauer, DN Bolon, BM Burton, RE Burton, JM Flynn, RA Grant, ... Cell 119 (1), 9-18, 2004 | 526 | 2004 |
| Proteomic profiling of ClpXP substrates after DNA damage reveals extensive instability within SOS regulon SB Neher, J Villén, EC Oakes, CE Bakalarski, RT Sauer, SP Gygi, ... Molecular cell 22 (2), 193-204, 2006 | 212 | 2006 |
| Latent ClpX-recognition signals ensure LexA destruction after DNA damage SB Neher, JM Flynn, RT Sauer, TA Baker Genes & development 17 (9), 1084-1089, 2003 | 156 | 2003 |
| Distinct peptide signals in the UmuD and UmuD′ subunits of UmuD/D′ mediate tethering and substrate processing by the ClpXP protease SB Neher, RT Sauer, TA Baker Proceedings of the National Academy of Sciences 100 (23), 13219-13224, 2003 | 139 | 2003 |
| Angiopoietin-like protein 4 inhibition of lipoprotein lipase: evidence for reversible complex formation MJ Lafferty, KC Bradford, DA Erie, SB Neher Journal of Biological Chemistry 288 (40), 28524-28534, 2013 | 105 | 2013 |
| Signal sequences activate the catalytic switch of SRP RNA N Bradshaw, SB Neher, DS Booth, P Walter science 323 (5910), 127-130, 2009 | 91 | 2009 |
| Heat Shock Transcription Factor σ32 Co-opts the Signal Recognition Particle to Regulate Protein Homeostasis in E. coli B Lim, R Miyazaki, S Neher, DA Siegele, K Ito, P Walter, Y Akiyama, ... PLoS Biology 11 (12), e1001735, 2013 | 83 | 2013 |
| Ligand-Controlled Proteolysis of the Escherichia coli Transcriptional Regulator ZntR M Pruteanu, SB Neher, TA Baker Journal of bacteriology 189 (8), 3017-3025, 2007 | 68 | 2007 |
| A dual apolipoprotein C-II mimetic–apolipoprotein C-III antagonist peptide lowers plasma triglycerides A Wolska, L Lo, DO Sviridov, M Pourmousa, M Pryor, SS Ghosh, R Kakkar, ... Science translational medicine 12 (528), eaaw7905, 2020 | 64 | 2020 |
| Protecting activity of desiccated enzymes S Piszkiewicz, KH Gunn, O Warmuth, A Propst, A Mehta, KH Nguyen, ... Protein Science 28 (5), 941-951, 2019 | 62 | 2019 |
| SRP RNA controls a conformational switch regulating the SRP–SRP receptor interaction SB Neher, N Bradshaw, SN Floor, JD Gross, P Walter Nature structural & molecular biology 15 (9), 916-923, 2008 | 49 | 2008 |
| Signal recognition particle-ribosome binding is sensitive to nascent chain length TR Noriega, A Tsai, MM Elvekrog, A Petrov, SB Neher, J Chen, ... Journal of Biological Chemistry 289 (28), 19294-19305, 2014 | 48 | 2014 |
| Mapping the sites of the lipoprotein lipase (LPL)–angiopoietin-like protein 4 (ANGPTL4) interaction provides mechanistic insight into LPL inhibition AR Gutgsell, SV Ghodge, AA Bowers, SB Neher Journal of Biological Chemistry 294 (8), 2678-5366, 2019 | 45 | 2019 |
| Lipase maturation factor LMF1, membrane topology and interaction with lipase proteins in the endoplasmic reticulum MH Doolittle, SB Neher, O Ben-Zeev, J Ling-Liao, CM Gallagher, ... Journal of biological chemistry 284 (48), 33623-33633, 2009 | 41 | 2009 |
| Biochemical Analysis of the Lipoprotein Lipase Truncation Variant, LPLS447X, Reveals Increased Lipoprotein Uptake CK Hayne, MJ Lafferty, BJ Eglinger, JP Kane, SB Neher Biochemistry 56 (3), 525-533, 2017 | 29 | 2017 |
| The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage KH Gunn, BS Roberts, F Wang, JD Strauss, MJ Borgnia, EH Egelman, ... Proceedings of the National Academy of Sciences 117 (19), 10254-10264, 2020 | 28 | 2020 |
| Modulation of the Activity of Mycobacterium tuberculosis LipY by Its PE Domain CK Garrett, LJ Broadwell, CK Hayne, SB Neher PloS one 10 (8), e0135447, 2015 | 25 | 2015 |
| Lipase maturation factor 1 affects redox homeostasis in the endoplasmic reticulum BS Roberts, MA Babilonia‐Rosa, LJ Broadwell, MJ Wu, SB Neher The EMBO journal 37 (19), e97379, 2018 | 23 | 2018 |
| Endoplasmic reticulum quality control in lipoprotein metabolism CM Koerner, BS Roberts, SB Neher Molecular and cellular endocrinology 498, 110547, 2019 | 21 | 2019 |
Tania BakerProfessor of Biology, MITVerified email at mit.edu
