Safety and tolerability of c-MET inhibitors in cancer A Puccini, NI Marín-Ramos, F Bergamo, M Schirripa, S Lonardi, HJ Lenz, ... Drug safety 42, 211-233, 2019 | 96 | 2019 |
Auranofin efficacy against MDR Streptococcus pneumoniae and Staphylococcus aureus infections L Aguinagalde, R Díez-Martínez, J Yuste, I Royo, C Gil, Í Lasa, ... Journal of Antimicrobial Chemotherapy 70 (9), 2608-2617, 2015 | 70 | 2015 |
Blocking Ras inhibition as an antitumor strategy NI Marín-Ramos, S Ortega-Gutiérrez, ML López-Rodríguez Seminars in Cancer Biology 54, 91-100, 2019 | 43 | 2019 |
Intratumoral delivery of bortezomib: impact on survival in an intracranial glioma tumor model W Wang, HY Cho, R Rosenstein-Sisson, NIM Ramos, R Price, K Hurth, ... Journal of neurosurgery 128 (3), 695-700, 2017 | 40 | 2017 |
A potent isoprenylcysteine carboxylmethyltransferase (ICMT) inhibitor improves survival in Ras-driven acute myeloid leukemia NI Marín-Ramos, M Balabasquer, FJ Ortega-Nogales, IR Torrecillas, ... Journal of Medicinal Chemistry 62 (13), 6035-6046, 2019 | 33 | 2019 |
NEO212 inhibits migration and invasion of glioma stem cells NI Marín-Ramos, TZ Thein, HY Cho, SD Swenson, W Wang, ... Molecular cancer therapeutics 17 (3), 625-637, 2018 | 28 | 2018 |
NEO212, a conjugate of temozolomide and perillyl alcohol, blocks the endothelial-to-mesenchymal transition in tumor-associated brain endothelial cells in glioblastoma NI Marín-Ramos, N Jhaveri, TZ Thein, RA Fayngor, TC Chen, FM Hofman Cancer letters 442, 170-180, 2019 | 26 | 2019 |
NEO100 enables brain delivery of blood-brain barrier-impermeable therapeutics TCC Weijun Wang, Nagore I Marín-Ramos, Haiping He, Shan Zeng, Hee-Yeon Cho ... Neuro-Oncology, 2020 | 23* | 2020 |
miR-18a inhibits BMP4 and HIF-1α normalizing brain arteriovenous malformations NI Marín-Ramos, TZ Thein, KB Ghaghada, TC Chen, SL Giannotta, ... Circulation research 127 (9), e210-e231, 2020 | 21 | 2020 |
New inhibitors of angiogenesis with antitumor activity in vivo NI Marín-Ramos, D Alonso, S Ortega-Gutierrez, FJ Ortega-Nogales, ... Journal of medicinal chemistry 58 (9), 3757-3766, 2015 | 20 | 2015 |
Isoprenylcysteine carboxylmethyltransferase-based therapy for Hutchinson–Gilford progeria syndrome B Marcos-Ramiro, A Gil-Ordóñez, NI Marín-Ramos, FJ Ortega-Nogales, ... ACS Central Science 7 (8), 1300-1310, 2021 | 19 | 2021 |
Enhanced brain delivery and therapeutic activity of trastuzumab after blood-brain barrier opening by NEO100 in mouse models of brain-metastatic breast cancer W Wang, H He, NI Marín-Ramos, S Zeng, SD Swenson, HY Cho, J Fu, ... Neuro-oncology 23 (10), 1656-1667, 2021 | 16* | 2021 |
Development of a nucleotide exchange inhibitor that impairs Ras oncogenic signaling NI Marín‐Ramos, C Piñar, H Vázquez‐Villa, M Martín‐Fontecha, ... Chemistry–A European Journal 23 (7), 1676-1685, 2017 | 12 | 2017 |
Inhibition of motility by NEO100 through the calpain-1/RhoA pathway NI Marín-Ramos, M Pérez-Hernández, A Tam, SD Swenson, HY Cho, ... Journal of Neurosurgery 133 (4), 1020-1031, 2019 | 10 | 2019 |
The rolipram–perillyl alcohol conjugate (NEO214) is a mediator of cell death through the death receptor pathway HY Cho, TZ Thein, W Wang, SD Swenson, RA Fayngor, M Ou, ... Molecular Cancer Therapeutics 18 (3), 517-530, 2019 | 9 | 2019 |
Pharmacokinetic properties of the temozolomide perillyl alcohol conjugate (NEO212) in mice HY Cho, S Swenson, TZ Thein, W Wang, NR Wijeratne, NI Marín-Ramos, ... Neuro-Oncology Advances 2 (1), vdaa160, 2020 | 6 | 2020 |
Cysteine-based 3-substituted 1, 5-benzoxathiepin derivatives: Two new classes of anti-proliferative agents N Mahfoudh, NI Marín-Ramos, AM Gil, AI Jimenez, D Choquesillo-Lazarte, ... Arabian Journal of Chemistry 11 (3), 426-441, 2018 | 6 | 2018 |
Novel inhibitors of the enzyme isoprenylcysteine carboxyl methyltransferase (ICMT) ML López-Rodríguez, S Ortega-Gutiérrez, M Martín-Fontecha, ... European Patent PCT, 2014 | 5 | 2014 |
CHAPTER THREE THE BLOOD BRAIN BARRIER: MOLECULAR AND CELLULAR FUNCTION NI MARÍN-RAMOS, TC CHEN Advances in Brain Vascular Research, 48, 2020 | 1 | 2020 |
NEO212: sub-cytotoxic doses capable of inhibiting glioma stem cell invasion NI Marín-Ramos, FM Hofman, TC Chen Oncoscience 5 (5-6), 148, 2018 | 1 | 2018 |